Graves' disease laboratory findings: Difference between revisions
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== Laboratory Findings == | == Laboratory Findings == | ||
Another sign of Graves' disease is [[hyperthyroidism]], i.e. over-production of the [[thyroid hormone|thyroid hormones]] T3 and T4. Although, [[hypothyroidism]] has also been associated and may be the causating factor in some patients. Hyperthyroidism can be confirmed by measuring elevated blood levels levels of free (unbound) T3 and T4. Other useful laboratory measurements include [[thyroid-stimulating hormone]] (TSH, low in Graves' disease due to negative feedback from the elevated T3 and T4), and protein-bound [[iodine]] (elevated). Thyroid-stimulating antibodies may also be detected [[serology|serologically]]. Thyroid-stimulating antibodies bind and stimulate the TSH receptor. Anti-TSHR ABs are 80-95% sensitive, 80-90% specific for Graves’. | *Another sign of Graves' disease is [[hyperthyroidism]], i.e. over-production of the [[thyroid hormone|thyroid hormones]] T3 and T4. Although, [[hypothyroidism]] has also been associated and may be the causating factor in some patients. Hyperthyroidism can be confirmed by measuring elevated blood levels levels of free (unbound) T3 and T4. | ||
*Other useful laboratory measurements include [[thyroid-stimulating hormone]] (TSH, low in Graves' disease due to negative feedback from the elevated T3 and T4), and protein-bound [[iodine]] (elevated). | |||
*Thyroid-stimulating antibodies may also be detected [[serology|serologically]]. Thyroid-stimulating antibodies bind and stimulate the TSH receptor. Anti-TSHR ABs are 80-95% sensitive, 80-90% specific for Graves’. | |||
==References== | ==References== | ||
Revision as of 16:26, 27 August 2012
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Overview
Laboratory Findings
- Another sign of Graves' disease is hyperthyroidism, i.e. over-production of the thyroid hormones T3 and T4. Although, hypothyroidism has also been associated and may be the causating factor in some patients. Hyperthyroidism can be confirmed by measuring elevated blood levels levels of free (unbound) T3 and T4.
- Other useful laboratory measurements include thyroid-stimulating hormone (TSH, low in Graves' disease due to negative feedback from the elevated T3 and T4), and protein-bound iodine (elevated).
- Thyroid-stimulating antibodies may also be detected serologically. Thyroid-stimulating antibodies bind and stimulate the TSH receptor. Anti-TSHR ABs are 80-95% sensitive, 80-90% specific for Graves’.