Aplastic anemia medical therapy: Difference between revisions
(/* Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols {{cite journal| author=Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC et al.| title=Guidelines for the diagnosis and management of aplas...) |
(/* Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols {{cite journal| author=Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC et al.| title=Guidelines for the diagnosis and management of aplas...) |
||
Line 59: | Line 59: | ||
}} | }} | ||
==Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols <ref name="pmid19673883">{{cite journal| author=Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC et al.| title=Guidelines for the diagnosis and management of aplastic anaemia. | journal=Br J Haematol | year= 2009 | volume= 147 | issue= 1 | pages= 43-70 | pmid=19673883 | doi=10.1111/j.1365-2141.2009.07842.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19673883 }} </ref> (DONOT EDIT)== | |||
{{cquote| | |||
===Trial Therapy or Clinical Research Protocols=== | |||
* The use of high dose [[cyclophosphamide]] without stem cell support is not recommended in the treatment of [[aplastic anaemia]]. | |||
* [[Mycophenolate mofetil]] ([[MMF]]) does not appear to be effective in the treatment of aplastic anaemia. | |||
* The routine use of long term G-CSF, or other haemopoietic growth factors, after ATG and [[ciclosporin]] is not recommended outside the setting of prospective clinical trials. | |||
}} | |||
==Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols <ref name="pmid19673883">{{cite journal| author=Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC et al.| title=Guidelines for the diagnosis and management of aplastic anaemia. | journal=Br J Haematol | year= 2009 | volume= 147 | issue= 1 | pages= 43-70 | pmid=19673883 | doi=10.1111/j.1365-2141.2009.07842.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19673883 }} </ref> (DONOT EDIT)== | ==Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols <ref name="pmid19673883">{{cite journal| author=Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC et al.| title=Guidelines for the diagnosis and management of aplastic anaemia. | journal=Br J Haematol | year= 2009 | volume= 147 | issue= 1 | pages= 43-70 | pmid=19673883 | doi=10.1111/j.1365-2141.2009.07842.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19673883 }} </ref> (DONOT EDIT)== | ||
Revision as of 15:44, 23 September 2012
Aplastic anemia Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Aplastic anemia medical therapy On the Web |
American Roentgen Ray Society Images of Aplastic anemia medical therapy |
Risk calculators and risk factors for Aplastic anemia medical therapy |
Editor-In-Chief: Aric Hall, M.D., Beth Israel Deaconess Medical Center, Boston, MA [1]
Overview
Medical therapy of aplastic anemia often includes a short course of anti-thymocyte globulin (ATG or anti-lymphocyte globulin) and several months of treatment with cyclosporin to modulate the immune system. Mild chemotherapy with agents such as cyclophosphamide and vincristine may also be effective. Antibodies therapy, such as ATG, targets T-cells, which are believed to attack the bone marrow. Steroids are generally ineffective.
Medical Therapy
Supportive Care in treatment of aplastic anemia [1] (DONOT EDIT)
“ |
Supportive Care
|
” |
Specific Treatment of Aplastic Anaemia: General Comments [1] (DONOT EDIT)
“ |
General Comments
|
” |
Specific Treatment of Aplastic Anaemia: Human Leucocyte Antigen (HLA)-identical Sibling Donor Transplantation [1] (DONOT EDIT)
“ |
Human Leucocyte Antigen (HLA)-identical Sibling Donor Transplantation
|
” |
Specific Treatment of Aplastic Anaemia: Immunosuppressive Therapy: ATG and Ciclosporin [1] (DONOT EDIT)
“ |
Immunosuppressive Therapy: ATG and Ciclosporin
|
” |
“ |
|
” |
Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols [1] (DONOT EDIT)
“ |
Trial Therapy or Clinical Research Protocols
|
” |
Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols [1] (DONOT EDIT)
“ |
Trial Therapy or Clinical Research Protocols
|
” |