Goodpasture syndrome pathophysiology: Difference between revisions
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As with many autoimmune conditions, the precise cause of Goodpasture’s Syndrome is not yet known. It is believed to be a type II [[hypersensitivity]] reaction to Goodpasture’s antigens on the cells of the [[glomerulus|glomeruli]] of the kidneys and the [[pulmonary alveolus|pulmonary alveoli]], specifically the basement membrane's (including a-3 chain of type IV collagen), whereby the immune system wrongly recognizes these cells as foreign and attacks and destroys them, as it would an invading [[pathogen]]. | As with many autoimmune conditions, the precise cause of Goodpasture’s Syndrome is not yet known. It is believed to be a type II [[hypersensitivity]] reaction to Goodpasture’s antigens on the cells of the [[glomerulus|glomeruli]] of the kidneys and the [[pulmonary alveolus|pulmonary alveoli]], specifically the basement membrane's (including a-3 chain of type IV collagen), whereby the immune system wrongly recognizes these cells as foreign and attacks and destroys them, as it would an invading [[pathogen]]. | ||
=== Pathology === | |||
[[Image:Goodpasture Disease.jpg|thumb|center|Goodpasture Disease<ref>http://picasaweb.google.com/mcmumbi/USMLEIIImages</ref>]] | |||
==References== | ==References== | ||
Revision as of 18:06, 24 September 2012
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Goodpasture syndrome Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Goodpasture syndrome pathophysiology On the Web |
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American Roentgen Ray Society Images of Goodpasture syndrome pathophysiology |
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Risk calculators and risk factors for Goodpasture syndrome pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
As with many autoimmune conditions, the precise cause of Goodpasture’s Syndrome is not yet known. It is believed to be a type II hypersensitivity reaction to Goodpasture’s antigens on the cells of the glomeruli of the kidneys and the pulmonary alveoli, specifically the basement membrane's (including a-3 chain of type IV collagen), whereby the immune system wrongly recognizes these cells as foreign and attacks and destroys them, as it would an invading pathogen.
Pathology
