Haff disease differential diagnosis: Difference between revisions
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==[[Haff disease differential diagnosis|Differentiating Haff disease from other Diseases]]== | |||
<ref name="pmid25678154">{{cite journal| author=Nance JR, Mammen AL| title=Diagnostic evaluation of rhabdomyolysis. | journal=Muscle Nerve | year= 2015 | volume= 51 | issue= 6 | pages= 793-810 | pmid=25678154 | doi=10.1002/mus.24606 | pmc=4437836 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25678154 }} </ref> | |||
Haff disease is known to cause '''rhabdomyolysis''', and therefore, it should be differentiated from other causes of rhabdomyolysis. There are numerous etiologies of rhabdomyolysis and they may be categorized based on the physical, non-physical and genetic factors. | |||
===Physical factors=== | |||
*[[Physical trauma|Trauma]] | |||
*Excessive muscular activity | |||
*[[Status epilepticus]] | |||
*High-grade [[fever]] | |||
*[[Heat stroke]] | |||
*[[Electric shock]] | |||
===Non-physical factors=== | |||
*Medication (e.g., [[AIDS antiretroviral drugs|anti-retroviral]], [[anti-histamine]], [[Antipsychotics|anti-psychotics]], [[antidepressants]], and [[statins]]) | |||
*[[Infection]] (bacterial, and viral) | |||
*Drugs (e.g., [[alcohol]], [[heroin]], [[cocaine]], [[methamphetamine]], [[Ecstasy (drug)|ecstasy]], and [[Lysergic acid diethylamide|LSD]]) | |||
*Electrolyte abnormalities (e.g., [[hypokalemia]], [[hypophosphatemia]], [[hyponatremia]], and [[hypernatremia]]) | |||
===Genetic factors=== | |||
*Autoimmune diseases (e.g., [[polymyositis and dermatomyositis]]) | |||
*Metabolic diseases (e.g., [[Diabetes mellitus|diabetes]], [[Thyroid disease|thyroid dysfunction]], [[primary hyperaldosteronism]], [[primary adrenal insufficiency]], [[central diabetes insipidus]], postpartum hypernatremia, and pituitary dysfunction). | |||
*Inherited conditions (e.g., [[Glycogen storage disease|glycogen storage disorders]], [[Fatty acid oxidation disorder|fatty acid oxidation disorders]], [[Mitochondrial myopathy|mitochondrial myopathies]], [[Muscular dystrophy|muscular dystrophies]], and RYR1- related myopathies) |
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References
Differentiating Haff disease from other Diseases
Haff disease is known to cause rhabdomyolysis, and therefore, it should be differentiated from other causes of rhabdomyolysis. There are numerous etiologies of rhabdomyolysis and they may be categorized based on the physical, non-physical and genetic factors.
Physical factors
- Trauma
- Excessive muscular activity
- Status epilepticus
- High-grade fever
- Heat stroke
- Electric shock
Non-physical factors
- Medication (e.g., anti-retroviral, anti-histamine, anti-psychotics, antidepressants, and statins)
- Infection (bacterial, and viral)
- Drugs (e.g., alcohol, heroin, cocaine, methamphetamine, ecstasy, and LSD)
- Electrolyte abnormalities (e.g., hypokalemia, hypophosphatemia, hyponatremia, and hypernatremia)
Genetic factors
- Autoimmune diseases (e.g., polymyositis and dermatomyositis)
- Metabolic diseases (e.g., diabetes, thyroid dysfunction, primary hyperaldosteronism, primary adrenal insufficiency, central diabetes insipidus, postpartum hypernatremia, and pituitary dysfunction).
- Inherited conditions (e.g., glycogen storage disorders, fatty acid oxidation disorders, mitochondrial myopathies, muscular dystrophies, and RYR1- related myopathies)
- ↑ Nance JR, Mammen AL (2015). "Diagnostic evaluation of rhabdomyolysis". Muscle Nerve. 51 (6): 793–810. doi:10.1002/mus.24606. PMC 4437836. PMID 25678154.