Polymyalgia rheumatica laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Polymyalgia rheumatica is a clinical diagnosis that is supported by laboratory tests. Elevation in [[C-reactive protein]] (CRP) and/or [[erythrocyte sedimentation rate]] (ESR) is essential for the diagnosis of PMR.<ref name="pmid22388996">{{cite journal| author=Dasgupta B, Cimmino MA, Maradit-Kremers H, Schmidt WA, Schirmer M, Salvarani C et al.| title=2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative. | journal=Ann Rheum Dis | year= 2012 | volume= 71 | issue= 4 | pages= 484-92 | pmid=22388996 | doi=10.1136/annrheumdis-2011-200329 | pmc=PMC3298664 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22388996 }} </ref> | Polymyalgia rheumatica (PMR) is a clinical diagnosis that is supported by laboratory tests. Elevation in [[C-reactive protein]] (CRP) and/or [[erythrocyte sedimentation rate]] (ESR) is essential for the diagnosis of PMR.<ref name="pmid22388996">{{cite journal| author=Dasgupta B, Cimmino MA, Maradit-Kremers H, Schmidt WA, Schirmer M, Salvarani C et al.| title=2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative. | journal=Ann Rheum Dis | year= 2012 | volume= 71 | issue= 4 | pages= 484-92 | pmid=22388996 | doi=10.1136/annrheumdis-2011-200329 | pmc=PMC3298664 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22388996 }} </ref> | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Revision as of 23:20, 1 June 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Polymyalgia rheumatica (PMR) is a clinical diagnosis that is supported by laboratory tests. Elevation in C-reactive protein (CRP) and/or erythrocyte sedimentation rate (ESR) is essential for the diagnosis of PMR.[1]
Laboratory Findings
- The following laboratory findings are characteristic of PMR:[1]
- Elevated C-reactive protein (CRP)
- Elevated erythrocyte sedimentation rate (ESR)
- Absence of rheumatoid factor (RF)
- Absence of anti-citrullinated protein antibody (ACPA)
- Other supporting laboratory findings are:
- Mild normochromic, normocytic anemia (during active phase)
- Normal white blood cell (WBC)
- Elevated platelet count
- Negative antinuclear antibody (ANA)
- Elevated alkaline phosphatase (detected in one third to half of patients with PMR associated with GCA)[2]
- Normal creatine kinase (CK)
- Normal aldolase
References
- ↑ 1.0 1.1 Dasgupta B, Cimmino MA, Maradit-Kremers H, Schmidt WA, Schirmer M, Salvarani C; et al. (2012). "2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative". Ann Rheum Dis. 71 (4): 484–92. doi:10.1136/annrheumdis-2011-200329. PMC 3298664. PMID 22388996.
- ↑ Kyle V (1991). "Laboratory investigations including liver in polymyalgia rheumatica/giant cell arteritis". Baillieres Clin Rheumatol. 5 (3): 475–84. PMID 1807822. Unknown parameter
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