Lymphangitis medical therapy: Difference between revisions
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===Acute Lymphangitis=== | ===Acute Lymphangitis=== | ||
====Empiric Therapy==== | ====Empiric Therapy==== | ||
<SMALL><font color="#FF4C4C">'''▸ Click on the following categories to expand treatment regimens.'''</font><ref name="pmid23466022">{{cite journal| author=Moran GJ, Abrahamian FM, Lovecchio F, Talan DA| title=Acute bacterial skin infections: developments since the 2005 Infectious Diseases Society of America (IDSA) guidelines. | journal=J Emerg Med | year= 2013 | volume= 44 | issue= 6 | pages= e397-412 | pmid=23466022 | doi=10.1016/j.jemermed.2012.11.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23466022 }} </ref> | <SMALL><font color="#FF4C4C">'''▸ Click on the following categories to expand treatment regimens.'''</font><ref name="pmid23466022">{{cite journal| author=Moran GJ, Abrahamian FM, Lovecchio F, Talan DA| title=Acute bacterial skin infections: developments since the 2005 Infectious Diseases Society of America (IDSA) guidelines. | journal=J Emerg Med | year= 2013 | volume= 44 | issue= 6 | pages= e397-412 | pmid=23466022 | doi=10.1016/j.jemermed.2012.11.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23466022 }} </ref><ref name="pmid21208910">{{cite journal| author=Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ et al.| title=Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. | journal=Clin Infect Dis | year= 2011 | volume= 52 | issue= 3 | pages= e18-55 | pmid=21208910 | doi=10.1093/cid/ciq146 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21208910 }} </ref> | ||
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====Pathogen Based Therapy==== | ====Pathogen Based Therapy==== | ||
<SMALL><font color="#FF4C4C">'''▸ Click on the following categories to expand treatment regimens.'''</font><ref name="pmid23466022">{{cite journal| author=Moran GJ, Abrahamian FM, Lovecchio F, Talan DA| title=Acute bacterial skin infections: developments since the 2005 Infectious Diseases Society of America (IDSA) guidelines. | journal=J Emerg Med | year= 2013 | volume= 44 | issue= 6 | pages= e397-412 | pmid=23466022 | doi=10.1016/j.jemermed.2012.11.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23466022 }} </ref> | <SMALL><font color="#FF4C4C">'''▸ Click on the following categories to expand treatment regimens.'''</font><ref name="pmid23466022">{{cite journal| author=Moran GJ, Abrahamian FM, Lovecchio F, Talan DA| title=Acute bacterial skin infections: developments since the 2005 Infectious Diseases Society of America (IDSA) guidelines. | journal=J Emerg Med | year= 2013 | volume= 44 | issue= 6 | pages= e397-412 | pmid=23466022 | doi=10.1016/j.jemermed.2012.11.050 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23466022 }} </ref><ref name="pmid21208910">{{cite journal| author=Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ et al.| title=Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. | journal=Clin Infect Dis | year= 2011 | volume= 52 | issue= 3 | pages= e18-55 | pmid=21208910 | doi=10.1093/cid/ciq146 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21208910 }} </ref> | ||
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<font color="#FFF"> | <font color="#FFF"> | ||
▸ ''' | ▸ '''Pasteurella''' | ||
</font> | </font> | ||
</div> | </div> | ||
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<font color="#FFF"> | <font color="#FFF"> | ||
▸ ''' | ▸ '''Spirillum Minus''' | ||
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Nafcillin]] or [[Oxacillin]] 1-2 g IV q4h'''''<BR> OR <BR> ▸ '''''[[Cefazolin]] 1 g IV q8h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]] 300-450 mg PO q8h or 600 mg/kg IV q8h'''''<BR> OR <BR> ▸ '''''[[Erythromycin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Dicloxacillin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Cephalexin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Doxycycline]] or [[Minocycline]] 100 mg PO q12h'''''<BR> OR <BR> ▸ '''''[[TMP-SMZ]] 1 or 2 double-strength tablets ((sulfamethoxazole 800 mg; trimethoprim 160 mg) PO q12h''''' | | style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Nafcillin]] or [[Oxacillin]] 1-2 g IV q4h'''''<BR> OR <BR> ▸ '''''[[Cefazolin]] 1 g IV q8h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]] 300-450 mg PO q8h or 600 mg/kg IV q8h'''''<BR> OR <BR> ▸ '''''[[Erythromycin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Dicloxacillin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Cephalexin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Doxycycline]] or [[Minocycline]] 100 mg PO q12h'''''<BR> OR <BR> ▸ '''''[[TMP-SMZ]] 1 or 2 double-strength tablets ((sulfamethoxazole 800 mg; trimethoprim 160 mg) PO q12h''''' | ||
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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | '''''Children age >28 days''''' | | style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | '''''Children age >28 days''''' | ||
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Vancomycin]] 30 mg/kg IV q12h'''''<BR> OR <BR> ▸ '''''[[Linezolid]] 600 mg IV/PO q12h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]] 300-450 mg PO q8h or 600 mg/kg IV q8h'''''<BR> OR <BR> ▸ '''''[[Daptomycin]] 4mg/kg IV q24h'''''<BR> OR <BR> ▸ '''''[[Doxycycline]] or [[Minocycline]] 100 mg PO q12h'''''<BR> OR <BR> ▸ '''''[[TMP-SMZ]] 1 or 2 double-strength tablets ((sulfamethoxazole 800 mg; trimethoprim 160 mg) PO q12h''''' | | style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Vancomycin]] 30 mg/kg IV q12h'''''<BR> OR <BR> ▸ '''''[[Linezolid]] 600 mg IV/PO q12h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]] 300-450 mg PO q8h or 600 mg/kg IV q8h'''''<BR> OR <BR> ▸ '''''[[Daptomycin]] 4mg/kg IV q24h'''''<BR> OR <BR> ▸ '''''[[Doxycycline]] or [[Minocycline]] 100 mg PO q12h'''''<BR> OR <BR> ▸ '''''[[TMP-SMZ]] 1 or 2 double-strength tablets ((sulfamethoxazole 800 mg; trimethoprim 160 mg) PO q12h''''' | ||
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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | '''''Children age >28 days''''' | | style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | '''''Children age >28 days''''' | ||
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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=center | ''''' | | valign=top | | ||
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! style="height: 30px; line-height: 30px; background: #4479BA; border: 0px; font-size: 100%; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5);" align=center | {{fontcolor|#FFF|Pasteurella}} | |||
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=center | '''''Preferred Regimen''''' | |||
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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | ''''' | | style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | '''''Adults''''' | ||
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[ | | style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Nafcillin]] or [[Oxacillin]] 1-2 g IV q4h'''''<BR> OR <BR> ▸ '''''[[Cefazolin]] 1 g IV q8h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]] 300-450 mg PO q8h or 600 mg/kg IV q8h'''''<BR> OR <BR> ▸ '''''[[Erythromycin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Dicloxacillin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Cephalexin]] 500 mg PO q6h'''''<BR> OR <BR> ▸ '''''[[Doxycycline]] or [[Minocycline]] 100 mg PO q12h'''''<BR> OR <BR> ▸ '''''[[TMP-SMZ]] 1 or 2 double-strength tablets ((sulfamethoxazole 800 mg; trimethoprim 160 mg) PO q12h''''' | ||
|- | |- | ||
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | '''''Children age >28 days''''' | | style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=left | '''''Children age >28 days''''' | ||
|- | |- | ||
| style=" | | style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Nafcillin]] or [[Oxacillin]] 100–150 mg/kg IV q6h'''''<BR> OR <BR> ▸ '''''[[Cefazolin]] 50 mg/kg IV q8h'''''<BR> OR <BR> ▸ '''''[[Clindamycin]] 10–20 mg/kg PO q8h or 25–40 mg/kg IV q8h'''''<BR> OR <BR> ▸ '''''[[Erythromycin]] 10 mg/kg PO q6h'''''<BR> OR <BR> ▸ '''''[[Dicloxacillin]] 25 mg/kg PO q6h'''''<BR> OR <BR> ▸ '''''[[Cephalexin]] 25 mg/kg PO q6h'''''<BR> OR <BR> ▸ '''''[[TMP-SMZ]] 8–12 mg/kg (based on trimethoprim component) IV q6h/PO q12h''''' | ||
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==References== | ==References== |
Revision as of 16:48, 2 June 2014
Lymphangitis Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Lymphangitis medical therapy On the Web |
American Roentgen Ray Society Images of Lymphangitis medical therapy |
Risk calculators and risk factors for Lymphangitis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]
Overview
Lymphangitis most often is an acute complication following an extension from the skin infection with the potential of a systemic spread. It has to be promptly treated with appropriate antibiotics along with analgesics, anti-inflammatory medications, warm and moist compresses. Certain conditions like nodular lymphagitis that is complicated by abscess and lymphedema with significant lymphatic obstruction may require surgical intervention.
Principles of Therapy
Therapy Based on Clinical Form
Acute Lymphangitis
Empiric Therapy
▸ Click on the following categories to expand treatment regimens.[1][2]
Mild - Moderate Acute Lymphangitis ▸ Adults ▸ Children age >28 days Severe Acute Lymphangitis ▸ Adults ▸ Children age >28 days |
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Pathogen Based Therapy
▸ Click on the following categories to expand treatment regimens.[1][2]
Bacteria ▸ Streptococcus Pyogenes ▸ Methicillin Sensitive Staphylococcus Aureus ▸ Methicillin Resistant Staphylococcus Aureus ▸ Pasteurella ▸ Spirillum Minus |
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References
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