Small cell carcinoma of the lung medical therapy: Difference between revisions

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===Extensive Stage===
===Extensive Stage===
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{{familytree | | | | | | | | | | | A01 | | | | | | | | | | }}
{{familytree | | | | | | | | | | | A01 | | | | | | | | | | A01= '''Extensive stage'''}}
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{{familytree | | | | | | | | | | | B01 | | | | | | | | | | }}
{{familytree | | | | | | | | | | | B01 | | | | | | | | | | B01= '''Is there symptomatic localized metastasis''' <br> '''OR''' <br> '''metastasis to the brains?'''}}
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{{familytree | | | C01 | | | | | | C02 | | | | | | C03 | | }}
{{familytree | | | C01 | | | | | | C02 | | | | | | C03 | | C01= No| C02= Yes, there is symptomatic localized metastasis| C03= Yes, there is brain metastasis}}
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Revision as of 12:19, 8 June 2014

Small Cell Carcinoma of the Lung Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Small Cell Carcinoma of the Lung from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Radiation Therapy

Surgery

Prevention

Future or Investigational Therapies

Case Studies

Case #1

Small cell carcinoma of the lung medical therapy On the Web

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Blogs on Small cell carcinoma of the lung medical therapy

Directions to Hospitals Treating Small cell carcinoma of the lung

Risk calculators and risk factors for Small cell carcinoma of the lung medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Patients with small cell carcinoma (SCC) of the lung have many treatment options. The selection depends on the stage of the tumor. The options are radiation therapy, chemotherapy, surgery, or a combination of these methods. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities. Because cancer treatments often damage healthy cells and tissues, side effects are common. Side effects may not be the same for each person, and they may change from one treatment session to the next.

Initial Medical Therapy

Limited Stage SCC

 
 
 
 
 
 
 
 
 
 
 
 
Limited stage SCC
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Clinical stage T(1-2),N(0)
 
 
 
 
 
 
 
 
 
Limited stage in excess of T(1-2),N(0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
What is the statuses of the pathologic mediastinal staging AND operability of the patient?
 
 
 
 
 
 
 
 
 
What is the performance status of the patient?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Negative pathologic mediastinal staging
AND
Patient is medically operable
 
 
 
 
 
Positive pathologic mediastinal staging
OR
Patient is medically operable
 
Good (PS 0-2)
 
Poor (PS 3-4) due to SCC
 
Poor (PS 3-4) not due to SCC
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Lobectomy
PLUS
Lymph node dissection or sampling
 
 
 
 
 
What is the performance status of the patient?
 
Chemotherapy
PLUS
Thoracic radiation therapy
 
Chemotherapy
WITH/WITHOUT
Thoracic radiation therapy
 
Individualized treatment
PLUS
supportive care
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
What is the status of involvement of the lymph nodes?
 
 
 
Good (PS 0-2)
 
Poor (PS 3-4) due to SCC
 
Poor (PS 3-4) not due to SCC
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N0
 
N+
 
Chemotherapy
PLUS
Thoracic radiation therapy
 
Chemotherapy
WITH/WITHOUT
Thoracic radiation therapy
 
Individualized treatment
PLUS
supportive care
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Chemotherapy
 
Chemotherapy
PLUS
Mediastinal radiotherapy
 
 

Extensive Stage

 
 
 
 
 
 
 
 
 
 
Extensive stage
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Is there symptomatic localized metastasis
OR
metastasis to the brains?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
Yes, there is symptomatic localized metastasis
 
 
 
 
 
Yes, there is brain metastasis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ I01 }}}
 
 
 
 
 
 
 
 
 
 

Adjuvant Medical Therapy

Therapy for Relapse or Palliative Therapy

References


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