Liposarcoma pathophysiology: Difference between revisions
Joao Silva (talk | contribs) |
Joao Silva (talk | contribs) No edit summary |
||
| Line 20: | Line 20: | ||
<!-- | <!-- | ||
Occasionally the fibrous component represents the vast majority of the neoplasm to the extent that lipogenic areas can be easily overlooked or even missed in a small tissue sample (Fig 4). | |||
| Line 51: | Line 51: | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
===Sclerosing Liposarcoma=== | |||
The particular [[histological]] finding in this type of well differentiated liposarcoma is the identification of distinctive [[stromal]] cells distributed across the tissue, and associated with lipoblasts filled with multiple [[vacuoles]]. This association forms a [[collagenous]] background of fibrillary appearance.<ref name="pmid10982304">{{cite journal| author=Dei Tos AP| title=Liposarcoma: new entities and evolving concepts. | journal=Ann Diagn Pathol | year= 2000 | volume= 4 | issue= 4 | pages= 252-66 | pmid=10982304 | doi=10.1053/adpa.2000.8133 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10982304 }} </ref> | |||
==References== | ==References== | ||
Revision as of 15:21, 19 September 2014
|
Liposarcoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Liposarcoma pathophysiology On the Web |
|
American Roentgen Ray Society Images of Liposarcoma pathophysiology |
|
Risk calculators and risk factors for Liposarcoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Pathogenesis
According to their class, each liposarcoma will have specific characteristics and pathogenesis:
Well Differentiated Liposarcoma
This type of liposarcoma occurs both at the limbs and retroperitoneum in equal frequency, and occasionally at the mediastinum and spermatic cord, representing about 45% of liposarcomas.[1]
According to the WHO classification described previously, well differentiated liposarcomas may be sub-classified into 3 types: sclerosing; adipocytic; and inflammatory.
Sclerosing Liposarcoma
Occurs most frequently at the retroperitoneum and paratesticular regions.
Adipocytic Liposarcoma
Inflammatory Liposarcoma
Dedifferentiated Liposarcoma
Myxoid Liposarcoma
Round Cell Liposarcoma
Pleomorphic Liposarcoma
Genetics
Associated Conditions
Gross Pathology
Microscopic Pathology
Sclerosing Liposarcoma
The particular histological finding in this type of well differentiated liposarcoma is the identification of distinctive stromal cells distributed across the tissue, and associated with lipoblasts filled with multiple vacuoles. This association forms a collagenous background of fibrillary appearance.[1]
References
- ↑ 1.0 1.1 Dei Tos AP (2000). "Liposarcoma: new entities and evolving concepts". Ann Diagn Pathol. 4 (4): 252–66. doi:10.1053/adpa.2000.8133. PMID 10982304.