Liposarcoma history and symptoms: Difference between revisions

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Liposarcoma usually presents as a  painless [[mass]]. The most common location of a liposarcoma is the lower [[extremities]].  Patients with [[retroperitoneal]] liposarcoma remain [[asymptomatic]] until the mass invades adjacent structures, which may cause [[pain]] or obstructive symptoms.
Liposarcoma usually presents as a  painless [[mass]]. The most common location of a liposarcoma is the lower [[extremities]].  Patients with [[retroperitoneal]] liposarcoma remain [[asymptomatic]] until the mass invades adjacent structures, which may cause [[pain]] or obstructive symptoms.


==History and Symptoms==
==History and symptoms==
* The symptoms of liposarcoma will depend on the location of the tumor.  
* Symptoms of liposarcoma will depend on the location of the tumor.  
* Liposarcomas located in the deep soft tissue of the extremities would be noted as a mass, and the primary complain would be a slow growing painless mass for several months.
* Liposarcomas located in the deep soft tissue of the extremities presents as a painless mass that grows slowly over several months.
* The most common location of superficial liposarcomas are the lower extremities, specially the tight and popliteal region.  
* Superficial liposarcomas are commonly located in the lower extremities, especially in the femoral and popliteal regions.  


===Retroperitoneal Liposarcoma===
===Retroperitoneal liposarcoma===
* Most patients with [[retroperitoneal]] liposarcomas remain asymptomatic until the tumor reaches a considerable size (10-20 cm).
* The majority of patients with [[retroperitoneal]] liposarcoma remain asymptomatic until the tumor grows to a considerable size (10-20 cm).
* Symptoms in a retroperitoneal liposarcomas include [[weight loss]], [[abdominal pain]].<ref name="GrassoMarino2014">{{cite journal|last1=Grasso|first1=Emanuele|last2=Marino|first2=Fabio|last3=Bottalico|first3=Michele|last4=Simone|first4=Michele|title=A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment|journal=Case Reports in Surgery|volume=2014|year=2014|pages=1–4|issn=2090-6900|doi=10.1155/2014/572805}}</ref>
* Common ymptoms of retroperitoneal liposarcoma include [[weight loss]] and [[abdominal pain]].<ref name="GrassoMarino2014">{{cite journal|last1=Grasso|first1=Emanuele|last2=Marino|first2=Fabio|last3=Bottalico|first3=Michele|last4=Simone|first4=Michele|title=A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment|journal=Case Reports in Surgery|volume=2014|year=2014|pages=1–4|issn=2090-6900|doi=10.1155/2014/572805}}</ref>
* Tumor may compress adjacent organs and vascular structures.<ref name="McGrath1994">{{cite journal|last1=McGrath|first1=Patrick C.|title=Retroperitoneal sarcomas|journal=Seminars in Surgical Oncology|volume=10|issue=5|year=1994|pages=364–368|issn=87560437|doi=10.1002/ssu.2980100509}}</ref>
* The tumor may compress adjacent organs and vascular structures to cause pain or obstructive symptoms.<ref name="McGrath1994">{{cite journal|last1=McGrath|first1=Patrick C.|title=Retroperitoneal sarcomas|journal=Seminars in Surgical Oncology|volume=10|issue=5|year=1994|pages=364–368|issn=87560437|doi=10.1002/ssu.2980100509}}</ref>
* The [[kidneys]] or [[ureters]] may be affected and this can cause [[oliguria]] and [[kidney failure]].
* The [[kidneys]] or [[ureters]] may also be involved, which may result in urologic symptoms, such as [[oliguria]], or [[renal failure]].


===Esophageal Liposarcoma===
===Esophageal liposarcoma===
* Esophageal liposarcomas may cause [[dysphagia]], [[vomiting]], [[cough]], [[gastrointestinal bleeding]] and [[hoarseness]], but they are extremely rare.<ref name="DowliMattar2014">{{cite journal|last1=Dowli|first1=A.|last2=Mattar|first2=A.|last3=Mashimo|first3=H.|last4=Huang|first4=Q.|last5=Cohen|first5=D.|last6=Fisichella|first6=P. M.|last7=Lebenthal|first7=A.|title=A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review|journal=Journal of Gastrointestinal Surgery|year=2014|issn=1091-255X|doi=10.1007/s11605-014-2628-8}}</ref>
*Esophageal liposarcoma is extremely rare.<ref name="DowliMattar2014">{{cite journal|last1=Dowli|first1=A.|last2=Mattar|first2=A.|last3=Mashimo|first3=H.|last4=Huang|first4=Q.|last5=Cohen|first5=D.|last6=Fisichella|first6=P. M.|last7=Lebenthal|first7=A.|title=A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review|journal=Journal of Gastrointestinal Surgery|year=2014|issn=1091-255X|doi=10.1007/s11605-014-2628-8}}</ref>
* Esophageal liposarcomas may cause [[dysphagia]], [[vomiting]], [[cough]], [[gastrointestinal bleeding]], and [[hoarseness]].<ref name="DowliMattar2014">{{cite journal|last1=Dowli|first1=A.|last2=Mattar|first2=A.|last3=Mashimo|first3=H.|last4=Huang|first4=Q.|last5=Cohen|first5=D.|last6=Fisichella|first6=P. M.|last7=Lebenthal|first7=A.|title=A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review|journal=Journal of Gastrointestinal Surgery|year=2014|issn=1091-255X|doi=10.1007/s11605-014-2628-8}}</ref>


===Bowel Liposarcoma===
===Bowel Liposarcoma===
*Symptoms of gastrointestinal [[bleeding]] could be a manifestation of liposarcoma located in the [[small bowel]] and [[colon]]. <ref>{{Cite journal
*Symptoms of gastrointestinal [[bleeding]] are common manifestations of liposarcoma located in the [[small bowel]] and the [[colon]].<ref>{{Cite journal
| author = [[Simon Nennstiel]], [[Martin Mollenhauer]], [[Christoph Schlag]], [[Valentin Becker]], [[Bruno Neu]], [[Norbert Huser]], [[Ralf Gertler]], [[Roland M. Schmid]] & [[Stefan von Delius]]
| author = [[Simon Nennstiel]], [[Martin Mollenhauer]], [[Christoph Schlag]], [[Valentin Becker]], [[Bruno Neu]], [[Norbert Huser]], [[Ralf Gertler]], [[Roland M. Schmid]] & [[Stefan von Delius]]
  | title = Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding
  | title = Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding
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===Mediastinal Liposarcoma===
===Mediastinal Liposarcoma===
*Mediastinal liposarcomas are rare, symptoms include [[dyspnea]], [[chest pain]], [[wheezing]], [[cough]] and [[weight loss]].<ref name="FukuharaDimitrova2014">{{cite journal|last1=Fukuhara|first1=Shinichi|last2=Dimitrova|first2=Kamellia R|last3=Geller|first3=Charles M|last4=Hoffman|first4=Darryl M|last5=Ko|first5=Wilson|last6=Tranbaugh|first6=Robert F|title=Progressive dyspnea in patient with large mediastinal mass|journal=Journal of Cardiothoracic Surgery|volume=9|issue=1|year=2014|pages=6|issn=1749-8090|doi=10.1186/1749-8090-9-6}}</ref>
*Mediastinal liposarcomas are rare
*Symptoms include [[dyspnea]], [[cough]], [[chest pain]], and [[weight loss]].<ref name="FukuharaDimitrova2014">{{cite journal|last1=Fukuhara|first1=Shinichi|last2=Dimitrova|first2=Kamellia R|last3=Geller|first3=Charles M|last4=Hoffman|first4=Darryl M|last5=Ko|first5=Wilson|last6=Tranbaugh|first6=Robert F|title=Progressive dyspnea in patient with large mediastinal mass|journal=Journal of Cardiothoracic Surgery|volume=9|issue=1|year=2014|pages=6|issn=1749-8090|doi=10.1186/1749-8090-9-6}}</ref>


==References==
==References==

Revision as of 18:51, 23 September 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Liposarcoma usually presents as a painless mass. The most common location of a liposarcoma is the lower extremities. Patients with retroperitoneal liposarcoma remain asymptomatic until the mass invades adjacent structures, which may cause pain or obstructive symptoms.

History and symptoms

  • Symptoms of liposarcoma will depend on the location of the tumor.
  • Liposarcomas located in the deep soft tissue of the extremities presents as a painless mass that grows slowly over several months.
  • Superficial liposarcomas are commonly located in the lower extremities, especially in the femoral and popliteal regions.

Retroperitoneal liposarcoma

  • The majority of patients with retroperitoneal liposarcoma remain asymptomatic until the tumor grows to a considerable size (10-20 cm).
  • Common ymptoms of retroperitoneal liposarcoma include weight loss and abdominal pain.[1]
  • The tumor may compress adjacent organs and vascular structures to cause pain or obstructive symptoms.[2]
  • The kidneys or ureters may also be involved, which may result in urologic symptoms, such as oliguria, or renal failure.

Esophageal liposarcoma

Bowel Liposarcoma

Mediastinal Liposarcoma

References

  1. Grasso, Emanuele; Marino, Fabio; Bottalico, Michele; Simone, Michele (2014). "A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment". Case Reports in Surgery. 2014: 1–4. doi:10.1155/2014/572805. ISSN 2090-6900.
  2. McGrath, Patrick C. (1994). "Retroperitoneal sarcomas". Seminars in Surgical Oncology. 10 (5): 364–368. doi:10.1002/ssu.2980100509. ISSN 8756-0437.
  3. 3.0 3.1 Dowli, A.; Mattar, A.; Mashimo, H.; Huang, Q.; Cohen, D.; Fisichella, P. M.; Lebenthal, A. (2014). "A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review". Journal of Gastrointestinal Surgery. doi:10.1007/s11605-014-2628-8. ISSN 1091-255X.
  4. Simon Nennstiel, Martin Mollenhauer, Christoph Schlag, Valentin Becker, Bruno Neu, Norbert Huser, Ralf Gertler, Roland M. Schmid & Stefan von Delius (2014). "Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding". Case reports in gastrointestinal medicine. 2014: 391871. doi:10.1155/2014/391871. PMID 25161780.
  5. Fukuhara, Shinichi; Dimitrova, Kamellia R; Geller, Charles M; Hoffman, Darryl M; Ko, Wilson; Tranbaugh, Robert F (2014). "Progressive dyspnea in patient with large mediastinal mass". Journal of Cardiothoracic Surgery. 9 (1): 6. doi:10.1186/1749-8090-9-6. ISSN 1749-8090.


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