Liposarcoma history and symptoms: Difference between revisions
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Liposarcoma usually presents as a painless [[mass]]. The most common location of a liposarcoma is the lower [[extremities]]. Patients with [[retroperitoneal]] liposarcoma remain [[asymptomatic]] until the mass invades adjacent structures, which may cause [[pain]] or obstructive symptoms. | Liposarcoma usually presents as a painless [[mass]]. The most common location of a liposarcoma is the lower [[extremities]]. Patients with [[retroperitoneal]] liposarcoma remain [[asymptomatic]] until the mass invades adjacent structures, which may cause [[pain]] or obstructive symptoms. | ||
==History and | ==History and symptoms== | ||
* | * Symptoms of liposarcoma will depend on the location of the tumor. | ||
* Liposarcomas located in the deep soft tissue of the extremities | * Liposarcomas located in the deep soft tissue of the extremities presents as a painless mass that grows slowly over several months. | ||
* | * Superficial liposarcomas are commonly located in the lower extremities, especially in the femoral and popliteal regions. | ||
===Retroperitoneal | ===Retroperitoneal liposarcoma=== | ||
* | * The majority of patients with [[retroperitoneal]] liposarcoma remain asymptomatic until the tumor grows to a considerable size (10-20 cm). | ||
* | * Common ymptoms of retroperitoneal liposarcoma include [[weight loss]] and [[abdominal pain]].<ref name="GrassoMarino2014">{{cite journal|last1=Grasso|first1=Emanuele|last2=Marino|first2=Fabio|last3=Bottalico|first3=Michele|last4=Simone|first4=Michele|title=A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment|journal=Case Reports in Surgery|volume=2014|year=2014|pages=1–4|issn=2090-6900|doi=10.1155/2014/572805}}</ref> | ||
* | * The tumor may compress adjacent organs and vascular structures to cause pain or obstructive symptoms.<ref name="McGrath1994">{{cite journal|last1=McGrath|first1=Patrick C.|title=Retroperitoneal sarcomas|journal=Seminars in Surgical Oncology|volume=10|issue=5|year=1994|pages=364–368|issn=87560437|doi=10.1002/ssu.2980100509}}</ref> | ||
* The [[kidneys]] or [[ureters]] may be | * The [[kidneys]] or [[ureters]] may also be involved, which may result in urologic symptoms, such as [[oliguria]], or [[renal failure]]. | ||
===Esophageal Liposarcoma=== | ===Esophageal liposarcoma=== | ||
* Esophageal liposarcomas may cause [[dysphagia]], [[vomiting]], [[cough]], [[gastrointestinal bleeding]] and [[hoarseness]] | *Esophageal liposarcoma is extremely rare.<ref name="DowliMattar2014">{{cite journal|last1=Dowli|first1=A.|last2=Mattar|first2=A.|last3=Mashimo|first3=H.|last4=Huang|first4=Q.|last5=Cohen|first5=D.|last6=Fisichella|first6=P. M.|last7=Lebenthal|first7=A.|title=A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review|journal=Journal of Gastrointestinal Surgery|year=2014|issn=1091-255X|doi=10.1007/s11605-014-2628-8}}</ref> | ||
* Esophageal liposarcomas may cause [[dysphagia]], [[vomiting]], [[cough]], [[gastrointestinal bleeding]], and [[hoarseness]].<ref name="DowliMattar2014">{{cite journal|last1=Dowli|first1=A.|last2=Mattar|first2=A.|last3=Mashimo|first3=H.|last4=Huang|first4=Q.|last5=Cohen|first5=D.|last6=Fisichella|first6=P. M.|last7=Lebenthal|first7=A.|title=A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review|journal=Journal of Gastrointestinal Surgery|year=2014|issn=1091-255X|doi=10.1007/s11605-014-2628-8}}</ref> | |||
===Bowel Liposarcoma=== | ===Bowel Liposarcoma=== | ||
*Symptoms of gastrointestinal [[bleeding]] | *Symptoms of gastrointestinal [[bleeding]] are common manifestations of liposarcoma located in the [[small bowel]] and the [[colon]].<ref>{{Cite journal | ||
| author = [[Simon Nennstiel]], [[Martin Mollenhauer]], [[Christoph Schlag]], [[Valentin Becker]], [[Bruno Neu]], [[Norbert Huser]], [[Ralf Gertler]], [[Roland M. Schmid]] & [[Stefan von Delius]] | | author = [[Simon Nennstiel]], [[Martin Mollenhauer]], [[Christoph Schlag]], [[Valentin Becker]], [[Bruno Neu]], [[Norbert Huser]], [[Ralf Gertler]], [[Roland M. Schmid]] & [[Stefan von Delius]] | ||
| title = Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding | | title = Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding | ||
Line 34: | Line 35: | ||
===Mediastinal Liposarcoma=== | ===Mediastinal Liposarcoma=== | ||
*Mediastinal liposarcomas are rare | *Mediastinal liposarcomas are rare | ||
*Symptoms include [[dyspnea]], [[cough]], [[chest pain]], and [[weight loss]].<ref name="FukuharaDimitrova2014">{{cite journal|last1=Fukuhara|first1=Shinichi|last2=Dimitrova|first2=Kamellia R|last3=Geller|first3=Charles M|last4=Hoffman|first4=Darryl M|last5=Ko|first5=Wilson|last6=Tranbaugh|first6=Robert F|title=Progressive dyspnea in patient with large mediastinal mass|journal=Journal of Cardiothoracic Surgery|volume=9|issue=1|year=2014|pages=6|issn=1749-8090|doi=10.1186/1749-8090-9-6}}</ref> | |||
==References== | ==References== |
Revision as of 18:51, 23 September 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Liposarcoma usually presents as a painless mass. The most common location of a liposarcoma is the lower extremities. Patients with retroperitoneal liposarcoma remain asymptomatic until the mass invades adjacent structures, which may cause pain or obstructive symptoms.
History and symptoms
- Symptoms of liposarcoma will depend on the location of the tumor.
- Liposarcomas located in the deep soft tissue of the extremities presents as a painless mass that grows slowly over several months.
- Superficial liposarcomas are commonly located in the lower extremities, especially in the femoral and popliteal regions.
Retroperitoneal liposarcoma
- The majority of patients with retroperitoneal liposarcoma remain asymptomatic until the tumor grows to a considerable size (10-20 cm).
- Common ymptoms of retroperitoneal liposarcoma include weight loss and abdominal pain.[1]
- The tumor may compress adjacent organs and vascular structures to cause pain or obstructive symptoms.[2]
- The kidneys or ureters may also be involved, which may result in urologic symptoms, such as oliguria, or renal failure.
Esophageal liposarcoma
- Esophageal liposarcoma is extremely rare.[3]
- Esophageal liposarcomas may cause dysphagia, vomiting, cough, gastrointestinal bleeding, and hoarseness.[3]
Bowel Liposarcoma
- Symptoms of gastrointestinal bleeding are common manifestations of liposarcoma located in the small bowel and the colon.[4]
Mediastinal Liposarcoma
- Mediastinal liposarcomas are rare
- Symptoms include dyspnea, cough, chest pain, and weight loss.[5]
References
- ↑ Grasso, Emanuele; Marino, Fabio; Bottalico, Michele; Simone, Michele (2014). "A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment". Case Reports in Surgery. 2014: 1–4. doi:10.1155/2014/572805. ISSN 2090-6900.
- ↑ McGrath, Patrick C. (1994). "Retroperitoneal sarcomas". Seminars in Surgical Oncology. 10 (5): 364–368. doi:10.1002/ssu.2980100509. ISSN 8756-0437.
- ↑ 3.0 3.1 Dowli, A.; Mattar, A.; Mashimo, H.; Huang, Q.; Cohen, D.; Fisichella, P. M.; Lebenthal, A. (2014). "A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review". Journal of Gastrointestinal Surgery. doi:10.1007/s11605-014-2628-8. ISSN 1091-255X.
- ↑ Simon Nennstiel, Martin Mollenhauer, Christoph Schlag, Valentin Becker, Bruno Neu, Norbert Huser, Ralf Gertler, Roland M. Schmid & Stefan von Delius (2014). "Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding". Case reports in gastrointestinal medicine. 2014: 391871. doi:10.1155/2014/391871. PMID 25161780.
- ↑ Fukuhara, Shinichi; Dimitrova, Kamellia R; Geller, Charles M; Hoffman, Darryl M; Ko, Wilson; Tranbaugh, Robert F (2014). "Progressive dyspnea in patient with large mediastinal mass". Journal of Cardiothoracic Surgery. 9 (1): 6. doi:10.1186/1749-8090-9-6. ISSN 1749-8090.