Aplastic anemia causes: Difference between revisions
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* Toxins, such as [[pesticides]], [[arsenic]], and [[benzene]]. | * Toxins, such as [[pesticides]], [[arsenic]], and [[benzene]]. | ||
* Radiation and chemotherapy | * Radiation and chemotherapy | ||
* Medicines, such as [[Albendazole]], [[Cefadroxil]], [[Chlorpromazine]], [[chloramphenicol]] (an antibiotic rarely used in the United States, [[Carbamazepine]], [[Hydroxychloroquine]], [[Methimazole]], [[Orphenadrine]], [[Oxcarbazepine]], [[Phenytoin]], [[Quinine]], [[Phenylbutazone]], [[Sulindac]], [[Sulfasalazine]], [[Valganciclovir hydrochloride]]. | * Medicines, such as [[Albendazole]], [[Cefadroxil]], [[Chlorpromazine]], [[chloramphenicol]] (an antibiotic rarely used in the United States, [[Carbamazepine]], [[Hydroxychloroquine]], [[Methimazole]], [[Orphenadrine]], [[Oxcarbazepine]], [[Phenytoin]], [[Quinine]], [[Phenylbutazone]], [[Sulindac]], [[Sulfadiazine]], [[Sulfasalazine]], [[Valganciclovir hydrochloride]]. | ||
* Infectious diseases, such as [[hepatitis]], [[Epstein-Barr virus]], [[cytomegalovirus]], [[parvovirus B19]], and [[HIV]]. | * Infectious diseases, such as [[hepatitis]], [[Epstein-Barr virus]], [[cytomegalovirus]], [[parvovirus B19]], and [[HIV]]. | ||
* [[Collagen vascular disease]] | * [[Collagen vascular disease]] | ||
Revision as of 15:02, 23 January 2015
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Aplastic anemia Microchapters |
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Aplastic anemia causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]
Overview
The cause of the damage can be acquired or inherited. Acquired aplastic anemia is more common, and sometimes it's only temporary. Inherited aplastic anemia is rare. More than half of the cases of aplastic anemia are idiopathic. Chemicals, drugs, viral infections, collagen vascular diseases, and thymoma can be implicated as the causative factor in the other cases. Some research suggests that stem cell damage may occur because the body's immune system attacks its own cells by mistake.
Causes
Acquired Causes
Many diseases, conditions, and factors can cause aplastic anemia, including:
- Toxins, such as pesticides, arsenic, and benzene.
- Radiation and chemotherapy
- Medicines, such as Albendazole, Cefadroxil, Chlorpromazine, chloramphenicol (an antibiotic rarely used in the United States, Carbamazepine, Hydroxychloroquine, Methimazole, Orphenadrine, Oxcarbazepine, Phenytoin, Quinine, Phenylbutazone, Sulindac, Sulfadiazine, Sulfasalazine, Valganciclovir hydrochloride.
- Infectious diseases, such as hepatitis, Epstein-Barr virus, cytomegalovirus, parvovirus B19, and HIV.
- Collagen vascular disease
- Thymoma
- Autoimmune disorders, such as lupus and rheumatoid arthritis.
- Pregnancy (aplastic anemia that occurs during pregnancy often goes away after delivery.)
- Metastaic involvement of bone marrow
Inherited Causes
Certain inherited conditions can damage the stem cells and lead to aplastic anemia. Examples include:
Drug Side Effect
- Cefadroxil
- Ceftazidime Cefaclor
- Cefaclor
- Dapsone
- Isoniazid
- Meprobamate
- Penicillamine
- Probenecid
- Tolbutamide
- Sulfasalazine