Fever of unknown origin diagnostic criteria: Difference between revisions
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==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
In 1961 Petersdorf and Beeson suggested the following criteria:<ref name="Mandell"> | In 1961, Petersdorf and Beeson suggested the following criteria:<ref name="Mandell"> | ||
[http://www.ppidonline.com/ Mandell's Principles and Practices of Infection Diseases] 6th Edition (2004) by Gerald L. Mandell MD, MACP, John E. Bennett MD, Raphael Dolin MD, ISBN 0-443-06643-4 · Hardback · 4016 Pages Churchill Livingstone </ref><ref name="Harrison">[http://books.mcgraw-hill.com/medical/harrisons/ Harrison's Principles of Internal Medicine] 16th Edition, The McGraw-Hill Companies, ISBN 0-07-140235-7</ref> | [http://www.ppidonline.com/ Mandell's Principles and Practices of Infection Diseases] 6th Edition (2004) by Gerald L. Mandell MD, MACP, John E. Bennett MD, Raphael Dolin MD, ISBN 0-443-06643-4 · Hardback · 4016 Pages Churchill Livingstone </ref><ref name="Harrison">[http://books.mcgraw-hill.com/medical/harrisons/ Harrison's Principles of Internal Medicine] 16th Edition, The McGraw-Hill Companies, ISBN 0-07-140235-7</ref> | ||
* Fever higher than 38.3°C ( | * Fever higher than 38.3°C (100.9°F) on several occasions | ||
* Persisting without diagnosis for at least 3 weeks | * Persisting without diagnosis for at least 3 weeks | ||
* At least 1 week's investigation in hospital | * At least 1 week's investigation in hospital | ||
==Classification== | |||
In 1991, Durack and Street proposed a revised definition in which cases of FUO are currently categorized into four subclasses: classic FUO, nosocomial (health care-associated) FUO, neutropenic (immune-deficient) FUO, and HIV-related FUO. | |||
===Classic FUO=== | |||
Fever (>38.3° C or >100.9° F) for >3 weeks with no identified cause after 3 days of hospital evaluation or ≥3 outpatient visits | |||
===Nosocomial (health care-associated) FUO=== | |||
Fever (>38.3° C or >100.9° F) in hospitalized patients receiving acute care and with no infection present or incubating on admission if the diagnosis remains uncertain after 3 days of appropriate evaluation | |||
===Neutropenic (immune-deficient) FUO=== | |||
Fever (>38.3° C or >100.9° F) in patients with immunodeficiencies if the diagnosis remains uncertain after 3 days of appropriate evaluation, including negative cultures after 48 hours | |||
===HIV-related FUO=== | |||
Fever (>38.3° C or >100.9° F) for >3 weeks in outpatients with confirmed HIV infection or >3 days in inpatients with confirmed HIV infection if the diagnosis remains uncertain after appropriate evaluation | |||
==References== | ==References== | ||
{{Reflist|2}} | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
Revision as of 19:05, 18 March 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Diagnostic Criteria
In 1961, Petersdorf and Beeson suggested the following criteria:[1][2]
- Fever higher than 38.3°C (100.9°F) on several occasions
- Persisting without diagnosis for at least 3 weeks
- At least 1 week's investigation in hospital
Classification
In 1991, Durack and Street proposed a revised definition in which cases of FUO are currently categorized into four subclasses: classic FUO, nosocomial (health care-associated) FUO, neutropenic (immune-deficient) FUO, and HIV-related FUO.
Classic FUO
Fever (>38.3° C or >100.9° F) for >3 weeks with no identified cause after 3 days of hospital evaluation or ≥3 outpatient visits
Nosocomial (health care-associated) FUO
Fever (>38.3° C or >100.9° F) in hospitalized patients receiving acute care and with no infection present or incubating on admission if the diagnosis remains uncertain after 3 days of appropriate evaluation
Neutropenic (immune-deficient) FUO
Fever (>38.3° C or >100.9° F) in patients with immunodeficiencies if the diagnosis remains uncertain after 3 days of appropriate evaluation, including negative cultures after 48 hours
Fever (>38.3° C or >100.9° F) for >3 weeks in outpatients with confirmed HIV infection or >3 days in inpatients with confirmed HIV infection if the diagnosis remains uncertain after appropriate evaluation
References
- ↑ Mandell's Principles and Practices of Infection Diseases 6th Edition (2004) by Gerald L. Mandell MD, MACP, John E. Bennett MD, Raphael Dolin MD, ISBN 0-443-06643-4 · Hardback · 4016 Pages Churchill Livingstone
- ↑ Harrison's Principles of Internal Medicine 16th Edition, The McGraw-Hill Companies, ISBN 0-07-140235-7