Fever of unknown origin laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
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A comprehensive and meticulous history (i.e. illness of family members, recent visit to the tropics, medication), repeated physical examination (i.e. [[skin rash]], [[eschar]], [[lymphadenopathy]], [[heart murmur]]) and a myriad of laboratory tests (serological, [[blood culture]], immunological) are the cornerstone of finding the cause. | A comprehensive and meticulous history (i.e. illness of family members, recent visit to the tropics, medication), repeated physical examination (i.e. [[skin rash]], [[eschar]], [[lymphadenopathy]], [[heart murmur]]) and a myriad of laboratory tests (serological, [[blood culture]], immunological) are the cornerstone of finding the cause. | ||
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==Laboratory | ===Laboratory Investigations of FUO=== | ||
* [[Complete blood count|Complete blood count with differential]] | * [[Complete blood count|Complete blood count with differential]] | ||
* [[Basic metabolic panel]] | * [[Basic metabolic panel]] | ||
Revision as of 19:11, 3 April 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; fever/pyrexia of obscured/undetermined/uncertain/unidentifiable/unknown focus/origin/source; fever/pyrexia without a focus/origin/source; FUO; PUO
Overview
Laboratory Investigations of FUO
- Complete blood count with differential
- Basic metabolic panel
- Liver function test including AST, ALT, LDH, bilirubin, and alkaline phosphatase
- Creatine kinase
- Blood cultures (at least 2 sets)
- Urinalysis with microscopic examination
- Urine cultures
- Erythrocyte sedimentation rate
- C-reactive protein
- Gamma-glutamyl transferase
- Coombs test
- Cold agglutinins
- Ferritin
- Angiotensin-converting enzyme
- Thyroid peroxidase and anti-thyroglobulin antibodies
- Antinuclear antibodies
- Rheumatoid factor
- Cryoglobulins
- Cytomegalovirus serology and heterophile antibody test if positive for atypical lymphocytes
- Q fever serology for patients with exposure to livestocks
- HIV serology
- Serum protein electrophoresis
- Tuberculin skin test
- Fecal occult blood test