Dyspepsia causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Causes

Common Causes

• Aerophagia

• Anxiety
• Gastroesophageal reflux
• Gastritis
• Irritable bowel syndrome
• Lactose intolerance
• Peptic ulcer

Causes by Organ system

Cardiovascular
Chemical / poisoning	Aluminium hydroxide, amanita phalloides, smoking, sodium dichloroisocyanurate, iron, potassium
Dermatologic	Herpes simplex
Drug Side Effect	4-Chlorodehydromethyltestosterone, acarbose, acetylsalicylic acid, achalasia, achillea millefolium, adefovir, alendronate, alpha-glucosidase inhibitor, alvimopan, amitriptyline, amlodipine, amlodipine and Benazepril, ampicillin, angiotensin converting enzyme inhibitors, angiotensin II receptor antagonist, aprotinin, artemether and lumefantrin, asenapine maleate, aspirin, atazanavir, bezafibrate, biguanide, bisphosphonates, buprenorphine, calcium channel blockers, caspofungin acetate, cefadroxil, cefixime, cholestyramine, cholestyramine resin, cidofovir, codeine , colchicine, collinsonia canadensis, colofac, corticosteroids, coptis, daptomycin, diflunisal, digitalis, digoxin, donepezil, dopamine agonist, duloxetine, efavirenz, eflornithine, eletriptan, elvitegravir, emtricitabine, epoetin alfa injection, eribulin, erythromycin, estrogen, ethosuximide, febuxostat, fentanyl skin patches, fesoterodine, fibrates, fluoxetine, fluticasone, fluvastatin, fluvoxamine, frovatriptan, gemfibrozil, glucocorticoids, H2 antagonist, heroin, iberogast, ibuprofen, imatinib, indomethacin, infliximab, interferon beta-1b injection, interferon gamma, ketorolac, lacosamide, levalbuterol, levodopa, lithium, lovaza, macrolides, meloxicam, meropenem, meropenem injection, metformin, methocarbamol, methylprednisolone, methylxanthin, metronidazole , misoprostol, monoamine oxidase-b inhibitors, mosapride, nabilone, nabumetone, nalbuphine, naproxen and esomeprazole magnesium, narcotics, niacin, nicotine polacrilex, non-steroidal anti-inflammatory drug, omeprazole, opioids, oprelvekin, oral contraceptives, orlistat, oxcarbazepine, oxycodone, oxycodone and aspirin, PDE5 inhibitor, pentamidine Isethionate, pergolide, pirfenidone, potassium supplements, pramlintide injection, prednisone, proton pump inhibitor, quazepam, quetiapine, quinidine, rasagiline, rimabotulinumtoxinb, rivastigmine, sertraline, sildenafil, simvastatin, sorafenib, steroid medications,strongyloides, sunitinib, tadalafil, tenofovir disoproxil fumarate, tetracycline, thalidomide, theophylline, thyroid medicines, tiotropium Oral inhalation), tobacco, tolmetin, topiramate, travoprost, triamcinolone acetonidevaldecoxib, valproic acid, venlafaxine, vigabatrin, vilazodone, vortioxetine, zolmitriptan, zopiclone
Ear Nose Throat	Thyroglossal cyst
Endocrine	Adrenal fatigue, carcinoid syndrome, diabetes mellitus, estrogens, hyperparathyroidism, hyperthyroidism, multiple endocrine neoplasia type 1, overeating, Parathyroid disorders, primary hyperparathyroidism, thyroid disease, thyroglossal cyst
Environmental	Multiple chemical sensitivity
Gastroenterologic	Achlorhydria, acid reflux , acute viral hepatitis, acute pancreatitis, adult hypertrophic pyloric stenosis, aerophagy, cholecystitis, chronic hepatitis, , cirrhosis of liver, coeliac disease, colonic cancer, crohn's disease, duodenal cancer, duodenal lymphoma, duodenal polyps, duodenal ulcer, duodenal webs, duodenitis, esophageal carcinoma, esophagitis, gallstones, gastric cancer, gastric lymphoma, gastric motility disorder, gastric ulcer, gastritis, gastroesophageal reflux disease, gastrointestinal tumors, hiatus hernia, hypertrophic gastritis, intestinal motility disorder, intestinal obstruction, irritable bowel syndrome, malabsorption, Ménétriér's disease, pancreatic cancer, peptic ulcers, small intestinal bacterial overgrowth, tropical sprue, ulcerative colitis, hepatoma, ischemic bowel diseaseAcid reflux , Acute and chronic pancreatitis, Acute gastric dilation, Acute viral hepatitis, Adult hypertrophic pyloric stenosis, Aerophagy, Amebic dysentery, Ascites, Biliary conditions , Biliary pain, Burping, Carbohydrate malabsorption, Carcinoid syndrome, Celiac arterycompressionsyndrome, Celiacdisease, Cholecystitis, Cholelithiasis, Chronic abdominal wall pain, Chronic gastritis , Chronic hepatitis, Chronic intestinal ischemia, Chronicpancreatitis, Coloncancer, Constipation, Crohn disease, Delayed gastric emptying, Diarrhea, Duodenal cancer, Duodenal lymphoma, Duodenalpolyps, Duodenalulcer, Duodenalwebs, Duodenitis, Esophagealcancer, Esophagealspasm, Esophagitis, Esophagogastroduodenoscopy, Esophagus diseases , Functional bowel disorder, Gallstones, Gas, Gastric cancer, Gastric lymphoma, Gastric motility disorder, Gastric ulcer, Gastritis, Gastroenteritis, Gastroesophageal reflux disease, Gastrointestinal mucormycosis, Gastrointestinal neoplasm, Gastrointestinal zygomycosis, Gastroparesis, Giardiasis, H. pylori, Helicobacter pylori infection, Hepatitis c, Hepatitis, Hepatocellular carcinoma, Hepatoma, Hiatal hernia, Inflammatory bowel disease, Intestinal motility disorder, Intestinal obstruction, Irritable bowel syndrome, Ischemic bowel disease, Lactose intolerance, Malabsorption, Ménétriér's disease, Non-ulcer dyspepsia, Oesophageal dysmotility, Pancreatic cancer, Pancreatitis, Peptic ulcer, Rome process, Small intestinal bacterial overgrowth, Stomach cancer, Superior mesenteric artery syndrome, Swallowed air, Tropical sprue, Ulcerative colitis, Visceroptosis
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	No underlying causes
Infectious Disease	Amebic dysentery, fascioliasis, gastrointestinal mucormycosis, giardiasis, H. Pylori, hookworm, opisthorchiasis, strongyloidiasis, syphilis, tuberculosis
Musculoskeletal / Ortho	No underlying causes
Neurologic	Autonomic neuropathy
Nutritional / Metabolic	Diabulimia, eating fatty foods, eating just before sleeping, eating spicy foods, eating too late in the evening, excess alcohol consumption, excess caffeine consumption, garlic, indian gooseberry, overeating, suillus luteus
Obstetric/Gynecologic	No underlying causes
Oncologic	Ovarian cancer, extranodal marginal zone B-cell Lymphoma of mucosa-associated lymphoid tissue, colonic cancer, duodenal cancer, duodenal lymphoma, esophageal carcinoma, gastric cancer, gastric lymphoma, gastrointestinal tumors, pancreatic cancer
Opthalmologic	No underlying causes
Overdose / Toxicity	Niacin, vitamin C
Psychiatric	No underlying causes
Pulmonary	Sarcoidosis, smoking, tuberculosis
Renal / Electrolyte	Hypercalcaemia, uremia
Rheum / Immune / Allergy	Oral allergy syndrome, sarcoidosis, scleroderma
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	Couvade, gulf War syndrome, alcohol, gas, stress, tobacco, obesity, SSRI discontinuation syndrome, Trichophagia

Causes in Alphabetical Order

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