Liposarcoma risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Common risk factors in the development of liposarcoma include chemical carcinogens, [[ | Common risk factors in the development of liposarcoma include chemical carcinogens, [[radiation]], [[immunodeficiency]], [[genetic disorders]], and [[Viral infection|viral infections]]. | ||
==Risk factors== | ==Risk factors== | ||
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**[[Basal cell carcinoma|Nevoid basal cell carcinoma]] (Gorlin syndrome) | **[[Basal cell carcinoma|Nevoid basal cell carcinoma]] (Gorlin syndrome) | ||
*[[Viral infection]] | *[[Viral infection|viral infections]] | ||
==References== | ==References== | ||
Revision as of 14:14, 26 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Common risk factors in the development of liposarcoma include chemical carcinogens, radiation, immunodeficiency, genetic disorders, and viral infections.
Risk factors
Liposarcoma is associated with a number of risk factors. Common risk factors in development of liposarcoma are:
- Chemical carcinogens
- Phenoxyacetic herbicides
- Chlorophenols
- Dioxin contaminations
- Arsenic
- Thorium dioxide (Thorotrast)
- Radiation
- Risk has been found with adjuvant therapy of radiation for breast carcinoma. Risk increases with dose and a dose of 50 GY or more of radiation has been recorded with increased risk of sarcoma. The mean period between exposure to radiation and tumor diagnosis is 10 years.
- Immunodeficiency
- Regional acquired immunodeficiency is sometimes associated with liposarcoma
- Genetic susceptibility
- Li-Fraumeni syndrome
- Neurofibromatosis (NF1; von Recklinghausen disease)
- Gardner syndrome (Familial adenomatous polyposis)
- Retinoblastoma
- Werner syndrome
- Nevoid basal cell carcinoma (Gorlin syndrome)