VIPoma medical therapy: Difference between revisions
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{{CMG}}{{AE}}{{PSD}} | {{CMG}}{{AE}}{{PSD}} | ||
==Overview== | ==Overview== | ||
Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. Steroids may be used to provide symptomatic relief.<ref name=sp>Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/</ref> | Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. [[Steroids]] may be used to provide symptomatic relief.<ref name=sp>Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/</ref> | ||
==Medical Therapy== | ==Medical Therapy== | ||
*Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. | *Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. | ||
*[[Sandostatin]] or [[chemotherapy]] must be considered for malignant tumors. | |||
*Sandostatin or chemotherapy must be considered for malignant tumors. | *[[Steroids]] may be used to provide symptomatic relief. | ||
*Prostaglandin synthesis inhibitors (e.g., [[indomethacin]]), [[phenothiazines]], and [[lithium]] combination may be used. | |||
*Steroids may be used to provide symptomatic relief. | *Long-term [[octreotide]] treatment not only controls the [[diarrhea]] in the patients with VIPoma but also may cause arrest or regression of the tumor. | ||
*Prostaglandin synthesis inhibitors (e.g., indomethacin), phenothiazines, and lithium combination may be used. | |||
*Long-term octreotide treatment not only controls the diarrhea in the patients with VIPoma but also may cause arrest or regression of the tumor. | |||
==References== | ==References== | ||
Revision as of 20:31, 27 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. Steroids may be used to provide symptomatic relief.[1]
Medical Therapy
- Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses.
- Sandostatin or chemotherapy must be considered for malignant tumors.
- Steroids may be used to provide symptomatic relief.
- Prostaglandin synthesis inhibitors (e.g., indomethacin), phenothiazines, and lithium combination may be used.
- Long-term octreotide treatment not only controls the diarrhea in the patients with VIPoma but also may cause arrest or regression of the tumor.
References
- ↑ Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/