Mast cell leukemia pathophysiology: Difference between revisions
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==Gross Pathology== | ==Gross Pathology== | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
==Immunohistochemistry== | |||
*Atypical mast cells express multiple surface antigens such as: | |||
:*CD117/kit | |||
:*CD11c | |||
:*CD13 | |||
:*CD29 | |||
:*CD33 | |||
:*CD44 | |||
:*CD45 | |||
:*CD63 | |||
:*CD68 | |||
:*CD71 | |||
:*CD2 | |||
:*CD22 | |||
:*CD25 | |||
:*CD54 | |||
*The role of these antigens is however not yet understood. | |||
*CD2 and CD25 antigens are important markers and their positivity on the surface of mast cells constitute minor criteria for the diagnosis of mast cell disease. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 20:40, 19 November 2015
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Mast cell leukemia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Mast cell leukemia pathophysiology On the Web |
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American Roentgen Ray Society Images of Mast cell leukemia pathophysiology |
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Risk calculators and risk factors for Mast cell leukemia pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Pathophysiology
Pathogenesis
Associated Conditions
Gross Pathology
Microscopic Pathology
Immunohistochemistry
- Atypical mast cells express multiple surface antigens such as:
- CD117/kit
- CD11c
- CD13
- CD29
- CD33
- CD44
- CD45
- CD63
- CD68
- CD71
- CD2
- CD22
- CD25
- CD54
- The role of these antigens is however not yet understood.
- CD2 and CD25 antigens are important markers and their positivity on the surface of mast cells constitute minor criteria for the diagnosis of mast cell disease.