Esthesioneuroblastoma history and symptoms: Difference between revisions

Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
Simrat Sarai (talk | contribs)
CMEUser, nocaptcha
5,683 edits
No edit summary
Simrat Sarai (talk | contribs)
CMEUser, nocaptcha
5,683 edits
No edit summary
Line 8: Line 8:
*The presenting symptoms of esthesioneuroblastoma depend on the location and extent of the tumor.  
*The presenting symptoms of esthesioneuroblastoma depend on the location and extent of the tumor.  
*The most common symptoms are nasal bleeding, unilateral nasal obstruction, headaches, decreased sense of smell, and facial pain.
*The most common symptoms are nasal bleeding, unilateral nasal obstruction, headaches, decreased sense of smell, and facial pain.
*Extension into the orbit may give rise to proptosis, double vision, tearing, and decreased visual acuity.
 
*Intracranial extension may lead to neurological symptoms such as changes in mental status, nausea and vomiting, headaches, seizures, and eventually coma and death.
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
*Obstruction of the eustachian tube may result in causing other symptoms such as ear pain and serous otitis media.
|valign=top|
*Nasal obstruction due to the presence of a mass is the most common symptom with olfactory neuroblastoma and is present in the majority of cases.
|+
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Location}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Features}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
:Nasal
| style="padding: 5px 5px; background: #F5F5F5;" |
*Nasal bleeding
*Unilateral nasal obstruction
*Headaches
*Decreased sense of smell
*Facial pain
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Orbital extention
| style="padding: 5px 5px; background: #F5F5F5;" |
*Proptosis
*Double vision
*Tearing
*Decreased viual acuity
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Intracranial extention
| style="padding: 5px 5px; background: #F5F5F5;" |
*Change in mental status
*Nausea
*Vomiting
*Headaches
*Seizures
*Coma and death
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Obstruction of the eustachian tube
| style="padding: 5px 5px; background: #F5F5F5;" |
*Ear pain
*Serous otitis media
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Oral
| style="padding: 5px 5px; background: #F5F5F5;" |
*Mobile tooth
*Non-healing tooth extraction site
*Ill-fitting dental prosthesis
*Ulceration
|-
|}
 
 
 
Other symptoms may include the following:<ref name="pmid19721769">{{cite journal| author=Ward PD, Heth JA, Thompson BG, Marentette LJ| title=Esthesioneuroblastoma: Results and Outcomes of a Single Institution's Experience. | journal=Skull Base | year= 2009 | volume= 19 | issue= 2 | pages= 133-40 | pmid=19721769 | doi=10.1055/s-0028-1096195 | pmc=PMC2671304 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19721769  }} </ref><ref name="pmid18469486">{{cite journal| author=Koo BK, An JH, Jeon KH, Choi SH, Cho YM, Jang HC et al.| title=Two cases of ectopic adrenocorticotropic hormone syndrome with olfactory neuroblastoma and literature review. | journal=Endocr J | year= 2008 | volume= 55 | issue= 3 | pages= 469-75 | pmid=18469486 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18469486  }} </ref><ref name="pmid18575019">{{cite journal| author=Sharma S, Lasheen W, Walsh D| title=Paraneoplastic refractory hypercalcemia due to advanced metastatic esthesioneuroblastoma. | journal=Rhinology | year= 2008 | volume= 46 | issue= 2 | pages= 153-5 | pmid=18575019 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18575019  }} </ref><ref name="pmid24170477">{{cite journal| author=Gabbay U, Leider-Trejo L, Marshak G, Gabbay M, Fliss DM| title=A case and a series of published cases of esthesioneuroblastoma (ENB) in which long-standing paraneoplastic SIADH had preceded ENB diagnosis. | journal=Ear Nose Throat J | year= 2013 | volume= 92 | issue= 10-11 | pages= E6 | pmid=24170477 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24170477  }} </ref><ref name="pmid26199564">{{cite journal| author=Kunc M, Gabrych A, Czapiewski P, Sworczak K| title=Paraneoplastic syndromes in olfactory neuroblastoma. | journal=Contemp Oncol (Pozn) | year= 2015 | volume= 19 | issue= 1 | pages= 6-16 | pmid=26199564 | doi=10.5114/wo.2015.46283 | pmc=PMC4507891 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26199564  }} </ref>  
Other symptoms may include the following:<ref name="pmid19721769">{{cite journal| author=Ward PD, Heth JA, Thompson BG, Marentette LJ| title=Esthesioneuroblastoma: Results and Outcomes of a Single Institution's Experience. | journal=Skull Base | year= 2009 | volume= 19 | issue= 2 | pages= 133-40 | pmid=19721769 | doi=10.1055/s-0028-1096195 | pmc=PMC2671304 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19721769  }} </ref><ref name="pmid18469486">{{cite journal| author=Koo BK, An JH, Jeon KH, Choi SH, Cho YM, Jang HC et al.| title=Two cases of ectopic adrenocorticotropic hormone syndrome with olfactory neuroblastoma and literature review. | journal=Endocr J | year= 2008 | volume= 55 | issue= 3 | pages= 469-75 | pmid=18469486 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18469486  }} </ref><ref name="pmid18575019">{{cite journal| author=Sharma S, Lasheen W, Walsh D| title=Paraneoplastic refractory hypercalcemia due to advanced metastatic esthesioneuroblastoma. | journal=Rhinology | year= 2008 | volume= 46 | issue= 2 | pages= 153-5 | pmid=18575019 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18575019  }} </ref><ref name="pmid24170477">{{cite journal| author=Gabbay U, Leider-Trejo L, Marshak G, Gabbay M, Fliss DM| title=A case and a series of published cases of esthesioneuroblastoma (ENB) in which long-standing paraneoplastic SIADH had preceded ENB diagnosis. | journal=Ear Nose Throat J | year= 2013 | volume= 92 | issue= 10-11 | pages= E6 | pmid=24170477 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24170477  }} </ref><ref name="pmid26199564">{{cite journal| author=Kunc M, Gabrych A, Czapiewski P, Sworczak K| title=Paraneoplastic syndromes in olfactory neuroblastoma. | journal=Contemp Oncol (Pozn) | year= 2015 | volume= 19 | issue= 1 | pages= 6-16 | pmid=26199564 | doi=10.5114/wo.2015.46283 | pmc=PMC4507891 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26199564  }} </ref>  
*Nasal obstruction
*Epistaxis
*Ear pain
*Otitis media
*Hyposmia
*Nasal discharge
*Facial pain
*Changes in vision
*Lacrimation
*Facial numbness
*Neck mass
*Anosmia
*Ectopic adrenocorticotropic hormone syndrome  
*Ectopic adrenocorticotropic hormone syndrome  
*Hypercalcemia  
*Hypercalcemia  

Revision as of 02:38, 27 January 2016

Esthesioneuroblastoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Esthesioneuroblastoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Esthesioneuroblastoma history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Esthesioneuroblastoma history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Esthesioneuroblastoma history and symptoms

CDC on Esthesioneuroblastoma history and symptoms

Esthesioneuroblastoma history and symptoms in the news

Blogs on Esthesioneuroblastoma history and symptoms

Directions to Hospitals Treating Esthesioneuroblastoma

Risk calculators and risk factors for Esthesioneuroblastoma history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

Symptoms of esthesioneuroblastoma include nasal obstruction, epistaxis, ear pain, otitis media, hyposmia, nasal discharge, facial pain, changes in vision, lacrimation, facial numbness, neck mass, and anosmia.[1][2][3][4][5]

History

Symptoms

  • The presenting symptoms of esthesioneuroblastoma depend on the location and extent of the tumor.
  • The most common symptoms are nasal bleeding, unilateral nasal obstruction, headaches, decreased sense of smell, and facial pain.
Location Features
Nasal
  • Nasal bleeding
  • Unilateral nasal obstruction
  • Headaches
  • Decreased sense of smell
  • Facial pain
Orbital extention
  • Proptosis
  • Double vision
  • Tearing
  • Decreased viual acuity
Intracranial extention
  • Change in mental status
  • Nausea
  • Vomiting
  • Headaches
  • Seizures
  • Coma and death
Obstruction of the eustachian tube
  • Ear pain
  • Serous otitis media
Oral
  • Mobile tooth
  • Non-healing tooth extraction site
  • Ill-fitting dental prosthesis
  • Ulceration


Other symptoms may include the following:[1][2][3][4][5]

  • Ectopic adrenocorticotropic hormone syndrome
  • Hypercalcemia
  • Syndrome of inappropriate antidiuretic hormone (SIADH)
  • Hyponatremia
  • Neurological paraneoplastic syndromes

References

  1. ↑ 1.0 1.1 Ward PD, Heth JA, Thompson BG, Marentette LJ (2009). "Esthesioneuroblastoma: Results and Outcomes of a Single Institution's Experience". Skull Base. 19 (2): 133–40. doi:10.1055/s-0028-1096195. PMC 2671304. PMID 19721769.
  2. ↑ 2.0 2.1 Koo BK, An JH, Jeon KH, Choi SH, Cho YM, Jang HC; et al. (2008). "Two cases of ectopic adrenocorticotropic hormone syndrome with olfactory neuroblastoma and literature review". Endocr J. 55 (3): 469–75. PMID 18469486.
  3. ↑ 3.0 3.1 Sharma S, Lasheen W, Walsh D (2008). "Paraneoplastic refractory hypercalcemia due to advanced metastatic esthesioneuroblastoma". Rhinology. 46 (2): 153–5. PMID 18575019.
  4. ↑ 4.0 4.1 Gabbay U, Leider-Trejo L, Marshak G, Gabbay M, Fliss DM (2013). "A case and a series of published cases of esthesioneuroblastoma (ENB) in which long-standing paraneoplastic SIADH had preceded ENB diagnosis". Ear Nose Throat J. 92 (10–11): E6. PMID 24170477.
  5. ↑ 5.0 5.1 Kunc M, Gabrych A, Czapiewski P, Sworczak K (2015). "Paraneoplastic syndromes in olfactory neuroblastoma". Contemp Oncol (Pozn). 19 (1): 6–16. doi:10.5114/wo.2015.46283. PMC 4507891. PMID 26199564.

Template:Central nervous system tumors

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Esthesioneuroblastoma_history_and_symptoms&oldid=1207510"