Esthesioneuroblastoma classification: Difference between revisions
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==Classification== | ==Classification== | ||
*Neuroblastomas proper | *Neuroblastomas proper | ||
**[[Neuroblastomas | **[[Neuroblastomas]] proper has a histologic presentation similar to that of peripheral neuroblastomas of childhood. | ||
**Esthesioneuroblastomas is composed of sheets of poorly demarcated groups of cells separated by fine connective tissue trabeculae. | **Esthesioneuroblastomas is composed of sheets of poorly demarcated groups of cells separated by fine connective tissue trabeculae. | ||
**The cells are small and typically show no mitotic activity.between the cells. | **The cells are small and typically show no mitotic activity.between the cells. | ||
Revision as of 15:07, 27 January 2016
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Esthesioneuroblastoma Microchapters | |
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Diagnosis | |
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Treatment | |
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Case Studies | |
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Esthesioneuroblastoma classification On the Web | |
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American Roentgen Ray Society Images of Esthesioneuroblastoma classification | |
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Risk calculators and risk factors for Esthesioneuroblastoma classification | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Based on the duration of symptoms, esthesioneuroblastoma may be classified into two subtypes neuroblastoma proper and [neuroendocrine carcinomas]].[1]
Classification
- Neuroblastomas proper
- Neuroblastomas proper has a histologic presentation similar to that of peripheral neuroblastomas of childhood.
- Esthesioneuroblastomas is composed of sheets of poorly demarcated groups of cells separated by fine connective tissue trabeculae.
- The cells are small and typically show no mitotic activity.between the cells.
- Rosettes of the Homer-Wright type are present.
- On electronic microscopy, there is the presence of a dendritic cytoplasmic process with accumulations of small core granules within the process.
- Neuroblastomas proper contain fibrillary material
- Neuroendocrine carcinomas.
- Neuroendocrine carcinomas is admixture with glands.
- In neuroendocrine carcinomas, a neurofibrillary component is absent, and the growth pattern is that of solid nests without rosettes.
- Dense core granules similar to those of neuroblastoma are present in the cytoplasm and cytoplasmic extensions.
References
- ↑ Min KW (1995). "Usefulness of electron microscopy in the diagnosis of "small" round cell tumors of the sinonasal region". Ultrastruct Pathol. 19 (5): 347–63. PMID 7483011.