Endometrial hyperplasia differential diagnosis: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
*Endometrial hyperplasia must be differentiated from the following which have similar appearances on an ultrasound: | *Endometrial hyperplasia must be differentiated from the following which have similar appearances on an ultrasound:<ref name="pmid8184058">{{cite journal| author=Hulka CA, Hall DA, McCarthy K, Simeone JF| title=Endometrial polyps, hyperplasia, and carcinoma in postmenopausal women: differentiation with endovaginal sonography. | journal=Radiology | year= 1994 | volume= 191 | issue= 3 | pages= 755-8 | pmid=8184058 | doi=10.1148/radiology.191.3.8184058 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8184058 }} </ref> | ||
===Pregnancy related=== | |||
*Early pregnancy prior to sac being visualized (<5 weeks of gestation) | |||
*Ectopic pregnancy (thickened endometrium and sometimes fluid collection or pseudogestational sac can be associated) | |||
*Retained products of conception | |||
**Heterogeneously thickened endometrium with increased vascularity | |||
**There may be fluid collections | |||
*Adherent intra-uterine blood clot (heterogeneous endometrium with no vascularity) | |||
*Molar pregnancy thickened with multiple small cystic spaces | |||
*Endometritis (prominent hyperechoic endometrium with of without fluid and debris) | |||
===Non-pregnancy related=== | |||
*Endometrial carcinoma (variable appearance) | |||
*Polycystic ovaries (usually uniformly hyperechoic and tends to be diffuse) | |||
*Endometrial polyp (usually hyperechoic, often focal, look for vascular stalk) | |||
*Tamoxifen related endometrial changes (variable appearances) | |||
*Hormone replacement therapy (HRT) in postmenopausal female | |||
*Intrauterine adhesions (irregular echogenic areas with focal thickening) | |||
*Ovarian tumours associated with endometrial thickening | |||
**Endometrioid carcinoma of the ovary | |||
*Granulosa cell ovarian cancer | |||
**Normal thickening during the secretory phase | **Normal thickening during the secretory phase | ||
**Sessile endometrial polyp( | **Sessile endometrial polyp or polyps (may contain cystic spaces) | ||
**Submucosal uterine fibroids | **Submucosal uterine fibroids | ||
**Endometrial cancer | **Endometrial cancer | ||
**Pregnancy (uterine as well as ectopic) | **Pregnancy (uterine as well as ectopic) | ||
*Endometrial hyperplasia must also be differentiated from the following: | |||
==References== | ==References== | ||
Revision as of 16:06, 3 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Differential Diagnosis
- Endometrial hyperplasia must be differentiated from the following which have similar appearances on an ultrasound:[1]
- Early pregnancy prior to sac being visualized (<5 weeks of gestation)
- Ectopic pregnancy (thickened endometrium and sometimes fluid collection or pseudogestational sac can be associated)
- Retained products of conception
**Heterogeneously thickened endometrium with increased vascularity
- There may be fluid collections
- Adherent intra-uterine blood clot (heterogeneous endometrium with no vascularity)
- Molar pregnancy thickened with multiple small cystic spaces
- Endometritis (prominent hyperechoic endometrium with of without fluid and debris)
- Endometrial carcinoma (variable appearance)
- Polycystic ovaries (usually uniformly hyperechoic and tends to be diffuse)
- Endometrial polyp (usually hyperechoic, often focal, look for vascular stalk)
- Tamoxifen related endometrial changes (variable appearances)
- Hormone replacement therapy (HRT) in postmenopausal female
- Intrauterine adhesions (irregular echogenic areas with focal thickening)
- Ovarian tumours associated with endometrial thickening
- Endometrioid carcinoma of the ovary
- Granulosa cell ovarian cancer
- Normal thickening during the secretory phase
- Sessile endometrial polyp or polyps (may contain cystic spaces)
- Submucosal uterine fibroids
- Endometrial cancer
- Pregnancy (uterine as well as ectopic)
- Endometrial hyperplasia must also be differentiated from the following:
References
- ↑ Hulka CA, Hall DA, McCarthy K, Simeone JF (1994). "Endometrial polyps, hyperplasia, and carcinoma in postmenopausal women: differentiation with endovaginal sonography". Radiology. 191 (3): 755–8. doi:10.1148/radiology.191.3.8184058. PMID 8184058.