Hemophilia A overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Hemophilia A''' is a [[blood]] [[coagulation|clotting]] disorder caused by a mutation of the [[factor VIII]] gene, leading to a deficiency in Factor VIII. It is the most common [[hemophilia]]. Inheritance is [[X-linked]] recessive; hence, males are affected while females are carriers or very rarely display a mild [[phenotype]]. 1 in 5,000 males are affected. | '''Hemophilia A''' is a [[blood]] [[coagulation|clotting]] disorder caused by a mutation of the [[factor VIII]] gene, leading to a deficiency in Factor VIII. It is the most common [[hemophilia]]. Inheritance is [[X-linked]] recessive; hence, males are affected while females are carriers or very rarely display a mild [[phenotype]]. 1 in 5,000 males are affected. | ||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating [Disease] from Other Diseases== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Screening== | |||
==Natural History, Complications, and Prognosis== | |||
===Natural History=== | |||
===Complications=== | |||
===Prognosis=== | |||
==Diagnosis== | |||
===Diagnostic Criteria=== | |||
===History and Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Imaging Findings=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
===Medical Therapy=== | |||
===Surgery=== | |||
===Prevention=== | |||
==References== | ==References== | ||
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{{WS}} | {{WS}} | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
Revision as of 18:15, 17 June 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hemophilia A is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia. Inheritance is X-linked recessive; hence, males are affected while females are carriers or very rarely display a mild phenotype. 1 in 5,000 males are affected.