Fibroma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

There is no classification system established for fibroma. Based on the pathophysiology and location of the tumor, fibroma may be classified into hard fibroma, soft fibroma, angiofibroma, cystic fibroma, chondromyxoid fibroma, desmoplastic fibroma, nonossifying fibroma, ossifying fibroma, nuchal fibroma, collagenous fibroma, fibroma of tendon sheath, perifollicular fibroma, pleomorphic fibroma, uterine fibroma, neurofibroma, and ovarian fibroma.

Classification

Based on the pathophysiology and location of the tumor fibroma may be classified into the following types, which is shown below in a tabular form:

Type of Fibroma	Features
Hard Fibroma	The hard fibroma (fibroma durum) consists of many fibers and a few cells, e.g. in the skin it is called dermatofibroma (fibroma simplex or nodulus cutaneous). A special form is the keloid, which derives from hyperplastic growth of scars.
Soft Fibroma	The soft fibroma (fibroma molle) or fibroma with a shaft (acrochordon, skin tag, fibroma pendulans) consist of many loosely connected cells and less fibrous tissue. They mostly appear on the neck, armpits or groin.
Other types of fibroma	The fibroma cavernosum or angiofibroma It consists of many dilated vessels, it is a vasoactive tumor occurring almost exclusively in adolescent males. The cystic fibroma (fibroma cysticum) It has central softening or dilated lymphatic vessels. Myxofibroma The myxofibroma (fibroma myxomatodes) is produced by liquefaction of the underlying soft tissue. Cemento-ossifying fibroma The cemento-ossifying fibroma is hard and fibrous, most frequently seen on the jaw or in the mouth, sometimes in connection with a fracture or another type of injury. Other fibromas: Chondromyxoid fibroma Desmoplastic fibroma Nonossifying fibroma Ossifying fibroma Nuchal fibroma Collagenous fibroma Fibroma of tendon sheath Perifollicular fibroma Pleomorphic fibroma Uterine fibroma Neurofibroma
Ovarian Fibroma	It appears in the sex cord-stromal tumor group of ovarian neoplasms. Upon gross pathological inspection, ovary fibromas are firm and white or tan. Variants with edema are especially likely to be associated with Meigs' syndrome. On microscopic examination, there are intersecting bundles of spindle cells producing collagen. There may be thecomatous areas (fibrothecoma). The presence of an ovarian fibroma can cause ovarian torsion in some cases.