VIPoma medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses. Steroids may be used to provide symptomatic relief.

Medical Therapy

• Initial treatment in patient with VIPoma is prompt replacement of fluid and electrolyte losses.
• Sandostatin or chemotherapy must be considered for malignant tumors.
• Steroids may be used to provide symptomatic relief.
• Prostaglandin synthesis inhibitors (e.g., indomethacin), phenothiazines, and lithium combination may be used.
• Long-term octreotide treatment not only controls the diarrhea in the patients with VIPoma but also may cause arrest or regression of the tumor.

References

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