Wilson's disease natural history, complications and prognosis: Difference between revisions
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===Complications=== | ===Complications=== | ||
* Common complications of Wilson's disease include the following: | * Common complications of Wilson's disease include the following: | ||
** Cirrhosis | |||
** Hepatocellular carcinoma | ** Hepatocellular carcinoma | ||
** Persistent the neurological manifestations | |||
** Renal complications as kidney stones and renal failure | |||
** Hemolytic anemia | |||
===Prognosis=== | ===Prognosis=== | ||
Revision as of 22:34, 17 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Natural History, Complications, and Prognosis
Natural history
- The symptoms of Wilson's disease usually develop between age of 5 and 35 years. However, the symptoms can be presented at any age onset.
- If left untreated, Wilson's disease will lead to death. The copper accumulation in the liver and the brain will end up with cirrhosis and severe dystonia respectively. [1]
Complications
- Common complications of Wilson's disease include the following:
- Cirrhosis
- Hepatocellular carcinoma
- Persistent the neurological manifestations
- Renal complications as kidney stones and renal failure
- Hemolytic anemia
Prognosis
- Prognosis of Wilson's disease is usually excellent with proper treatment except in the severely advanced patients.
References
- ↑ European Association for Study of Liver (2012). "EASL Clinical Practice Guidelines: Wilson's disease". J Hepatol. 56 (3): 671–85. doi:10.1016/j.jhep.2011.11.007. PMID 22340672.