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{{PBB|geneid=170572}}
{{Infobox_gene}}


'''5-hydroxytryptamine receptor 3C''' is a [[protein]] that in humans is encoded by the ''HTR3C'' [[gene]].<ref name="pmid12801637">{{cite journal | author = Niesler B, Frank B, Kapeller J, Rappold GA | title = Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E | journal = Gene | volume = 310 | issue =  | pages = 101–11 | year = 2003 | month = Jun | pmid = 12801637 | pmc =  | doi =10.1016/S0378-1119(03)00503-1  }}</ref><ref name="pmid15157181">{{cite journal | author = Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ | title = The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance | journal = Biochem Soc Trans | volume = 32 | issue = Pt3 | pages = 547–52 | year = 2004 | month = May | pmid = 15157181 | pmc =  | doi = 10.1042/BST0320547 }}</ref><ref name="pmid12801637">{{cite journal | author = Niesler B, Frank B, Kapeller J, Rappold GA | title = Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E | journal = Gene | volume = 310 | issue = | pages = 101–11 | year = 2003 | month = May | pmid = 12801637 | doi = 10.1016/S0378-1119(03)00503-1| url = http://linkinghub.elsevier.com/retrieve/pii/S0378111903005031 | issn = }}</ref>  The protein encoded by this gene is a subunit of the [[5-HT3 receptor]].<ref name="pmid15157181">{{cite journal | author = Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ | title = The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance | journal = Biochem. Soc. Trans. | volume = 32 | issue = Pt3 | pages = 547–52 | year = 2004 | month = June | pmid = 15157181 | doi = 10.1042/BST0320547 | url = | issn = }}</ref>
'''5-hydroxytryptamine receptor 3C''' is a [[protein]] that in humans is encoded by the ''HTR3C'' [[gene]].<ref name="pmid12801637">{{cite journal |vauthors=Niesler B, Frank B, Kapeller J, Rappold GA | title = Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E | journal = Gene | volume = 310 | issue =  | pages = 101–11 |date=Jun 2003 | pmid = 12801637 | pmc =  | doi =10.1016/S0378-1119(03)00503-1  }}</ref><ref name="pmid12801637" /><ref name="pmid15157181">{{cite journal |vauthors=Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ | title = The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance | journal = Biochem Soc Trans | volume = 32 | issue = Pt3 | pages = 547–52 |date=May 2004 | pmid = 15157181 | pmc =  | doi = 10.1042/BST0320547 }}</ref>  The protein encoded by this gene is a subunit of the [[5-HT3 receptor]].<ref name="pmid15157181" />


==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
*{{cite journal |author=Karnovsky AM, Gotow LF, McKinley DD, ''et al.'' |title=A cluster of novel serotonin receptor 3-like genes on human chromosome 3. |journal=Gene |volume=319 |issue=  |pages= 137–48 |year= 2003 |pmid= 14597179 |doi=10.1016/S0378-1119(03)00803-5  }}
*{{cite journal   |vauthors=Karnovsky AM, Gotow LF, McKinley DD, etal |title=A cluster of novel serotonin receptor 3-like genes on human chromosome 3. |journal=Gene |volume=319 |issue=  |pages= 137–48 |year= 2003 |pmid= 14597179 |doi=10.1016/S0378-1119(03)00803-5  }}
*{{cite journal |author=Fasching PA, Kollmannsberger B, Strissel PL, ''et al.'' |title=Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. |journal=J. Cancer Res. Clin. Oncol. |volume=134 |issue= 10 |pages= 1079–86 |year= 2008 |pmid= 18389280 |doi= 10.1007/s00432-008-0387-1 }}
*{{cite journal   |vauthors=Fasching PA, Kollmannsberger B, Strissel PL, etal |title=Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. |journal=J. Cancer Res. Clin. Oncol. |volume=134 |issue= 10 |pages= 1079–86 |year= 2008 |pmid= 18389280 |doi= 10.1007/s00432-008-0387-1 }}
*{{cite journal  |author=Ward MB, Kotasek D, McKinnon RA |title=Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy. |journal=Pharmacogenomics |volume=9 |issue= 8 |pages= 1027–33 |year= 2008 |pmid= 18681779 |doi= 10.2217/14622416.9.8.1027 }}
*{{cite journal  |vauthors=Ward MB, Kotasek D, McKinnon RA |title=Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy. |journal=Pharmacogenomics |volume=9 |issue= 8 |pages= 1027–33 |year= 2008 |pmid= 18681779 |doi= 10.2217/14622416.9.8.1027 }}
{{refend}}
{{refend}}


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* {{MeshName|HTR3C+protein,+human}}
* {{MeshName|HTR3C+protein,+human}}


{{transmembranereceptor-stub}}
{{Ligand-gated ion channels}}
{{Ligand-gated ion channels}}
[[Category:Neurotransmitters]]
 
[[Category:Serotonin receptors]]
[[Category:Ion channels]]
[[Category:Ion channels]]
[[Category:Ionotropic receptors]]
 
 
{{transmembranereceptor-stub}}

Latest revision as of 22:32, 3 April 2017

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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RefSeq (protein)

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Wikidata
View/Edit Human

5-hydroxytryptamine receptor 3C is a protein that in humans is encoded by the HTR3C gene.[1][1][2] The protein encoded by this gene is a subunit of the 5-HT3 receptor.[2]

References

  1. ↑ 1.0 1.1 Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene. 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.
  2. ↑ 2.0 2.1 Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ (May 2004). "The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance". Biochem Soc Trans. 32 (Pt3): 547–52. doi:10.1042/BST0320547. PMID 15157181.

Further reading

  • Karnovsky AM, Gotow LF, McKinley DD, et al. (2003). "A cluster of novel serotonin receptor 3-like genes on human chromosome 3". Gene. 319: 137–48. doi:10.1016/S0378-1119(03)00803-5. PMID 14597179.
  • Fasching PA, Kollmannsberger B, Strissel PL, et al. (2008). "Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy". J. Cancer Res. Clin. Oncol. 134 (10): 1079–86. doi:10.1007/s00432-008-0387-1. PMID 18389280.
  • Ward MB, Kotasek D, McKinnon RA (2008). "Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy". Pharmacogenomics. 9 (8): 1027–33. doi:10.2217/14622416.9.8.1027. PMID 18681779.

External links


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