Familial adenomatous polyposis classification: Difference between revisions
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Familial adenomatous polyposis has less severe variants, including: | Familial adenomatous polyposis has less severe variants, including: | ||
Revision as of 18:11, 25 January 2018
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Familial adenomatous polyposis Microchapters |
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Differentiating Familial adenomatous polyposis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]
Overview
Familial adenomatous polyposis (FAP) may be classified according to the affected gene into two subtypes including FAP gene and MYH gene associated familial adenomatous polyposis. Familial adenomatous polyposis may be classified according to severity into two subtypes of classic and attenuated.
Classification
Familial adenomatous polyposis may be classified according to the affected genes into two subtypes:[1][2]
Familial adenomatous polyposis may be classified according to severity into three subtypes:[3]
- Profuse familial adenomatous polyposis
- Intermediate familial adenomatous polyposis
- Attenuated familial adenomatous polyposis
| Type | Characteristics | Age of onset |
|---|---|---|
| Profuse | Thousands of polyps | 2nd decade |
| Intermediate | Hundreds to thousands of polyps | 3rd decade |
| Attenuated | Less than 100 polyps | 5th decade |
Familial adenomatous polyposis has less severe variants, including:
References
- ↑ Iaquinto, Gaetano; Fornasarig, Mara; Quaia, Michele; Giardullo, Nicola; D'Onofrio, Vittorio; Iaquinto, Salvatore; Di Bella, Simone; Cannizzaro, Renato (2008). "Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis". Gastrointestinal Endoscopy. 67 (1): 61–67. doi:10.1016/j.gie.2007.07.048. ISSN 0016-5107.
- ↑ King, John E.; Dozois, Roger R.; Lindor, Noralane M.; Ahlquist, David A. (2000). "Care of Patients and Their Families With Familial Adenomatous Polyposis". Mayo Clinic Proceedings. 75 (1): 57–67. doi:10.4065/75.1.57. ISSN 0025-6196.
- ↑ Nieuwenhuis, M.H.; Vasen, H.F.A. (2007). "Correlations between mutation site in APC and phenotype of familial adenomatous polyposis (FAP): A review of the literature". Critical Reviews in Oncology/Hematology. 61 (2): 153–161. doi:10.1016/j.critrevonc.2006.07.004. ISSN 1040-8428.