Familial adenomatous polyposis surgery: Difference between revisions

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==Overview==
==Overview==
Surgery is the mainstay of treatment for familial adenomatous polyposis. The preferred surgery technique is laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) with a mucosectomy and anal anastomosis.
[[Surgery]] is the mainstay of treatment for familial adenomatous polyposis. The preferred [[surgery]] technique is [[Laparoscopic surgery|laparoscopic]] total [[proctocolectomy]] with ileal pouch anal [[anastomosis]] (IPAA) and mucosectomy.
==Indications==
==Indications==
*Surgery is recommended in patients with:<ref name="KennedyPotter2014">{{cite journal|last1=Kennedy|first1=Raelene D.|last2=Potter|first2=D. Dean|last3=Moir|first3=Christopher R.|last4=El-Youssef|first4=Mounif|title=The natural history of familial adenomatous polyposis syndrome: A 24year review of a single center experience in screening, diagnosis, and outcomes|journal=Journal of Pediatric Surgery|volume=49|issue=1|year=2014|pages=82–86|issn=00223468|doi=10.1016/j.jpedsurg.2013.09.033}}</ref><ref name="pmid10630758">{{cite journal |vauthors=King JE, Dozois RR, Lindor NM, Ahlquist DA |title=Care of patients and their families with familial adenomatous polyposis |journal=Mayo Clin. Proc. |volume=75 |issue=1 |pages=57–67 |year=2000 |pmid=10630758 |doi=10.4065/75.1.57 |url=}}</ref>
*Surgery is recommended in patients with:<ref name="KennedyPotter2014">{{cite journal|last1=Kennedy|first1=Raelene D.|last2=Potter|first2=D. Dean|last3=Moir|first3=Christopher R.|last4=El-Youssef|first4=Mounif|title=The natural history of familial adenomatous polyposis syndrome: A 24year review of a single center experience in screening, diagnosis, and outcomes|journal=Journal of Pediatric Surgery|volume=49|issue=1|year=2014|pages=82–86|issn=00223468|doi=10.1016/j.jpedsurg.2013.09.033}}</ref><ref name="pmid10630758">{{cite journal |vauthors=King JE, Dozois RR, Lindor NM, Ahlquist DA |title=Care of patients and their families with familial adenomatous polyposis |journal=Mayo Clin. Proc. |volume=75 |issue=1 |pages=57–67 |year=2000 |pmid=10630758 |doi=10.4065/75.1.57 |url=}}</ref>
**Diffuse polyposis  
**Diffuse [[Polyp|polyposis]]
**High-grade dysplasia on colonoscopy
**High-grade [[dysplasia]] on [[colonoscopy]]
**Invasive adenocarcinoma on colonoscopy
**Invasive [[adenocarcinoma]] on [[colonoscopy]]
**
==Surgery==
==Surgery==
* Surgery is the mainstay of treatment for familial adenomatous polyposis.
* [[Surgery]] is the mainstay of treatment for familial adenomatous polyposis.  
* There are several surgical options that involve the removal of either the colon or both the [[colon]] and [[rectum]].  
* The preferred surgical technique is:
* The preferred surgical technique is:
** Laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) with a mucosectomy and anal anastomosis which has:<ref name="KennedyPotter2014">{{cite journal|last1=Kennedy|first1=Raelene D.|last2=Potter|first2=D. Dean|last3=Moir|first3=Christopher R.|last4=El-Youssef|first4=Mounif|title=The natural history of familial adenomatous polyposis syndrome: A 24year review of a single center experience in screening, diagnosis, and outcomes|journal=Journal of Pediatric Surgery|volume=49|issue=1|year=2014|pages=82–86|issn=00223468|doi=10.1016/j.jpedsurg.2013.09.033}}</ref>
** Laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) and mucosectomy which has:<ref name="KennedyPotter2014">{{cite journal|last1=Kennedy|first1=Raelene D.|last2=Potter|first2=D. Dean|last3=Moir|first3=Christopher R.|last4=El-Youssef|first4=Mounif|title=The natural history of familial adenomatous polyposis syndrome: A 24year review of a single center experience in screening, diagnosis, and outcomes|journal=Journal of Pediatric Surgery|volume=49|issue=1|year=2014|pages=82–86|issn=00223468|doi=10.1016/j.jpedsurg.2013.09.033}}</ref>
*** Good patient satisfaction
*** Good patient satisfaction
*** Excellent functional outcome
*** Excellent functional outcome
*** Few postoperative complications
*** Few postoperative complications
*** No colorectal occurrence or recurrence
*** No [[Colon (anatomy)|colorectal]] occurrence or recurrence
{{#ev:youtube|bDXsdaZl9hQ}}
{{#ev:youtube|bDXsdaZl9hQ}}
* Other surgical techniques include:
* Other surgical techniques include:
** Total colectomy with ileorectal anastomosis
** Total [[colectomy]] with ileorectal [[anastomosis]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 17:03, 31 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]

Overview

Surgery is the mainstay of treatment for familial adenomatous polyposis. The preferred surgery technique is laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) and mucosectomy.

Indications

Surgery

  • Surgery is the mainstay of treatment for familial adenomatous polyposis.
  • The preferred surgical technique is:
    • Laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) and mucosectomy which has:[1]
      • Good patient satisfaction
      • Excellent functional outcome
      • Few postoperative complications
      • No colorectal occurrence or recurrence

{{#ev:youtube|bDXsdaZl9hQ}}

References

  1. 1.0 1.1 Kennedy, Raelene D.; Potter, D. Dean; Moir, Christopher R.; El-Youssef, Mounif (2014). "The natural history of familial adenomatous polyposis syndrome: A 24year review of a single center experience in screening, diagnosis, and outcomes". Journal of Pediatric Surgery. 49 (1): 82–86. doi:10.1016/j.jpedsurg.2013.09.033. ISSN 0022-3468.
  2. King JE, Dozois RR, Lindor NM, Ahlquist DA (2000). "Care of patients and their families with familial adenomatous polyposis". Mayo Clin. Proc. 75 (1): 57–67. doi:10.4065/75.1.57. PMID 10630758.