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== Causes==
== Causes==
Following are the causes of odynophagia.<ref name="pmid29364802">{{cite journal| author=Salgado C, Garcia AM, Rúbio C, Cunha F| title=[Infectious Mononucleosis and Cholestatic Hepatitis: A Rare Association]. | journal=Acta Med Port | year= 2017 | volume= 30 | issue= 12 | pages= 886-888 | pmid=29364802 | doi=10.20344/amp.8715 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29364802  }}</ref><ref name="pmid29318797">{{cite journal| author=So H, Park BH, Jang K, Baek H, Kim YJ| title=Esophagogastric Crohn's Disease Manifested by Life-Threatening Odynophagia and Chest Pain: a Case Report. | journal=J Korean Med Sci | year= 2018 | volume= 33 | issue= 4 | pages= e30 | pmid=29318797 | doi=10.3346/jkms.2018.33.e30 | pmc=5760815 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29318797  }}</ref><ref name="pmid29310719">{{cite journal| author=Eskander A, Monteiro E, O'Connell D, Taylor SM, Canadian Association of Head and Neck Surgical Oncology (CAHNSO)| title=Head and Neck Surgical Oncology Choosing Wisely Campaign: imaging for patients with hoarseness, fine needle aspiration for neck mass, and ultrasound for odynophagia. | journal=J Otolaryngol Head Neck Surg | year= 2018 | volume= 47 | issue= 1 | pages= 2 | pmid=29310719 | doi=10.1186/s40463-017-0251-x | pmc=5759226 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29310719  }}</ref><ref name="pmid29292712">{{cite journal| author=Gonzales Zamora JA, Espinoza LA| title=Histoplasma and Cytomegalovirus Coinfection of the Gastrointestinal Tract in a Patient with AIDS: A Case Report and Review of the Literature. | journal=Diseases | year= 2017 | volume= 5 | issue= 4 | pages=  | pmid=29292712 | doi=10.3390/diseases5040030 | pmc=5750541 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29292712  }}</ref>
Following are the causes of odynophagia.<ref name="pmid29364802">{{cite journal| author=Salgado C, Garcia AM, Rúbio C, Cunha F| title=[Infectious Mononucleosis and Cholestatic Hepatitis: A Rare Association]. | journal=Acta Med Port | year= 2017 | volume= 30 | issue= 12 | pages= 886-888 | pmid=29364802 | doi=10.20344/amp.8715 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29364802  }}</ref><ref name="pmid29318797">{{cite journal| author=So H, Park BH, Jang K, Baek H, Kim YJ| title=Esophagogastric Crohn's Disease Manifested by Life-Threatening Odynophagia and Chest Pain: a Case Report. | journal=J Korean Med Sci | year= 2018 | volume= 33 | issue= 4 | pages= e30 | pmid=29318797 | doi=10.3346/jkms.2018.33.e30 | pmc=5760815 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29318797  }}</ref><ref name="pmid29310719">{{cite journal| author=Eskander A, Monteiro E, O'Connell D, Taylor SM, Canadian Association of Head and Neck Surgical Oncology (CAHNSO)| title=Head and Neck Surgical Oncology Choosing Wisely Campaign: imaging for patients with hoarseness, fine needle aspiration for neck mass, and ultrasound for odynophagia. | journal=J Otolaryngol Head Neck Surg | year= 2018 | volume= 47 | issue= 1 | pages= 2 | pmid=29310719 | doi=10.1186/s40463-017-0251-x | pmc=5759226 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29310719  }}</ref><ref name="pmid29292712">{{cite journal| author=Gonzales Zamora JA, Espinoza LA| title=Histoplasma and Cytomegalovirus Coinfection of the Gastrointestinal Tract in a Patient with AIDS: A Case Report and Review of the Literature. | journal=Diseases | year= 2017 | volume= 5 | issue= 4 | pages=  | pmid=29292712 | doi=10.3390/diseases5040030 | pmc=5750541 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29292712 }}</ref><ref name="pmid29276680">{{cite journal| author=Miranda C, Jaker MA, Fitzhugh-Kull VA, Dever LL| title=Oropharyngeal histoplasmosis: The diagnosis lies in the biopsy. | journal=IDCases | year= 2018 | volume= 11 | issue=  | pages= 33-35 | pmid=29276680 | doi=10.1016/j.idcr.2017.12.005 | pmc=5738199 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29276680  }}</ref><ref name="pmid29264291">{{cite journal| author=Jalisi S, Jamal BT, Grillone GA| title=Surgical Management of Long-standing Eagle's Syndrome. | journal=Ann Maxillofac Surg | year= 2017 | volume= 7 | issue= 2 | pages= 232-236 | pmid=29264291 | doi=10.4103/ams.ams_53_17 | pmc=5717900 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29264291  }}</ref><ref name="pmid29264290">{{cite journal| author=Jalisi S, Sakai O, Jamal BT, Mardirossian V| title=Features of Prevertebral Disease in Patients Presenting to a Head and Neck Surgery Clinic with Neck Pain. | journal=Ann Maxillofac Surg | year= 2017 | volume= 7 | issue= 2 | pages= 228-231 | pmid=29264290 | doi=10.4103/ams.ams_54_17 | pmc=5717899 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29264290  }}</ref><ref name="pmid29255766">{{cite journal| author=Marques S, Carmo J, Pinto D, Bispo M, Ramos S, Chagas C| title=Cytomegalovirus Disease of the Upper Gastrointestinal Tract: A 10-Year Retrospective Study. | journal=GE Port J Gastroenterol | year= 2017 | volume= 24 | issue= 6 | pages= 262-268 | pmid=29255766 | doi=10.1159/000479232 | pmc=5731150 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29255766  }}</ref><ref name="pmid29206327">{{cite journal| author=Rama-López J, Tomás-Fernandez M, García-Garza C, Martínez-Madrigal M| title=Pharyngeal perforation after anterior cervical spine surgery treated by transoral endoscopic surgery. | journal=Head Neck | year= 2018 | volume= 40 | issue= 2 | pages= E13-E16 | pmid=29206327 | doi=10.1002/hed.25030 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29206327  }}</ref><ref name="pmid29198289">{{cite journal| author=Kato MG, Isaac MJ, Gillespie MB, O'Rourke AK| title=The Incidence and Characterization of Globus Sensation, Dysphagia, and Odynophagia Following Surgery for Obstructive Sleep Apnea. | journal=J Clin Sleep Med | year= 2018 | volume= 14 | issue= 1 | pages= 127-132 | pmid=29198289 | doi=10.5664/jcsm.6898 | pmc=5734881 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29198289  }}</ref><ref name="pmid29168645">{{cite journal| author=Teixeira C, Alves AL, Cremers I| title=Esophageal lichen planus: a rare case. | journal=Rev Esp Enferm Dig | year= 2018 | volume= 110 | issue= 1 | pages= 67-68 | pmid=29168645 | doi=10.17235/reed.2017.5332/2017 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29168645  }}</ref><ref name="pmid29146495">{{cite journal| author=Chen L, Lai Y, Dong L, Kang S, Chen X| title=Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis. | journal=Microb Pathog | year= 2017 | volume= 113 | issue=  | pages= 365-371 | pmid=29146495 | doi=10.1016/j.micpath.2017.11.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29146495  }}</ref><ref name="pmid29145245">{{cite journal| author=Kim YJ, Park JY, Choi KY, Moon BJ, Lee JK| title=Case reports about an overlooked cause of neck pain: calcific tendinitis of the longus colli: Case reports. | journal=Medicine (Baltimore) | year= 2017 | volume= 96 | issue= 46 | pages= e8343 | pmid=29145245 | doi=10.1097/MD.0000000000008343 | pmc=5704790 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29145245 }}</ref>


===Common Causes===
===Common Causes===

Revision as of 14:42, 5 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]

Causes

Following are the causes of odynophagia.[1][2][3][4][5][6][7][8][9][10][11][12][13]

Common Causes

Causes by Organ System

Cardiovascular Aortic aneurysm, Double aortic arch, Enlarged left atrium, Mediastinitis, Mitral valve stenosis
Chemical / poisoning Botulism, Chemical burns
Dermatologic Scleroderma
Drug Side Effect ibandronate, Stevens-Johnson Syndrome
Ear Nose Throat Cricopharyngeal spasm, Epiglottitis, Esophagotracheal fistula, Glossitis, Goiter, Gum disease, Laryngitis, Oral submucous fibrosis, Oral ulcers, Palatoplegia, Stomatitis, Zenker's Diverticulum, Herpangina, Retropharyngeal abscess, Palate cancer, Supraglottic laryngeal cancer , Xerostomia
Endocrine Diabetic neuropathy, Hyperthyroidism, Hypothyroidism, Riedel thyroiditis
Environmental No underlying causes
Gastroenterologic Achalasia, Barrett's oesophagus, Diverticulum, Esophageal achalasia, Esophageal atresia, Esophageal spasm, Esophageal stricture, Esophagitis, Fibrosis, Gastritis, Gastroesophageal reflux, Intramural pseudodiverticulosis, Peptic stenosis, Schatzki ring, Myoneurogastrointestinal encephalopathy syndrome, Crohn's disease, Eosinophilic esophagitis
Genetic Opitz-Frias syndrome
Hematologic Agranulocytosis, Lymphadenopathy
Iatrogenic Radiation esophagitis
Infectious Disease Abscesses, Acute pharyngitis, Adenoiditis, Angina tonsillaris, Candidiasis, Chagas Disease, Cytomegalovirus, Diphtheria, Esophageal moniliasis, Flu, Herpangina, Herpes simplex virus (HSV), Herpes stomatitis, HIV/AIDS, Mononucleosis, Mumps, Oral candidiasis, Paracoccidioidomycosis, Pharyngitis, Poliomyelitis, Rabies, Reflux esophagitis, Respiratory tract infections, Retropharyngeal abscess, Scarlet Fever, Tetanus, Tonsillar abscess, Tooth infection, Typhoid fever
Musculoskeletal / Ortho Elongated styloid process, Extreme spinal curvature, Global hystericus, Schatzki ring, Leiomyoma, Dermatomyositis, Myasthenia Gravis
Neurologic Amyotrophic Lateral Sclerosis (ALS), Brainstem stroke, Bulbar palsy, Central hypoglossal nerve paralysis, Central vagal nucleus lesion, Cerebrovascular accident, Guillain-Barre syndrome, Huntington's chorea, Multiple Sclerosis, Myoneurogastrointestinal encephalopathy syndrome, Neuroferritinopathy, Peripheral neuropathy, Polyradiculitis, Syringobulbia, Vagal disorder, Diabetic neuropathy, Poliomyelitis
Nutritional / Metabolic Gaucher's disease, Plummer-Vinson Syndrome
Obstetric/Gynecologic No underlying causes
Oncologic Bronchial carcinoma, Carcinoma of the vocal tract, Carotid body tumor, Esophageal cancer, Gastric tumors, Hypopharyngeal cancer, Laryngeal cancer, Leiomyoma, Oral cancer, Palate cancer, Paraneoplastic syndrome, Supraglottic laryngeal cancer
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric Anxiety disorders
Pulmonary Bronchial carcinoma
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Allergic swelling, Amyloidosis, Behcet's Syndrome, CREST syndrome , Crohn's disease, Dermatomyositis, Eosinophilic esophagitis, Esophageal sarcoidosis, Graft versus host reaction, Inclusion body myositis, Myasthenia Gravis, Parkinson's Disease, Riedel thyroiditis, Rheumatoid Arthritis, Scleroderma, Systemic Lupus Erythematosus, Systemic sclerosis, Xerostomia
Sexual No underlying causes
Trauma Esophageal trauma
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Alcoholism, Aspiration of foreign body

Causes in Alphabetical Order [14] [15]


References

  1. ↑ Salgado C, Garcia AM, Rúbio C, Cunha F (2017). "[Infectious Mononucleosis and Cholestatic Hepatitis: A Rare Association]". Acta Med Port. 30 (12): 886–888. doi:10.20344/amp.8715. PMID 29364802.
  2. ↑ So H, Park BH, Jang K, Baek H, Kim YJ (2018). "Esophagogastric Crohn's Disease Manifested by Life-Threatening Odynophagia and Chest Pain: a Case Report". J Korean Med Sci. 33 (4): e30. doi:10.3346/jkms.2018.33.e30. PMC 5760815. PMID 29318797.
  3. ↑ Eskander A, Monteiro E, O'Connell D, Taylor SM, Canadian Association of Head and Neck Surgical Oncology (CAHNSO) (2018). "Head and Neck Surgical Oncology Choosing Wisely Campaign: imaging for patients with hoarseness, fine needle aspiration for neck mass, and ultrasound for odynophagia". J Otolaryngol Head Neck Surg. 47 (1): 2. doi:10.1186/s40463-017-0251-x. PMC 5759226. PMID 29310719.
  4. ↑ Gonzales Zamora JA, Espinoza LA (2017). "Histoplasma and Cytomegalovirus Coinfection of the Gastrointestinal Tract in a Patient with AIDS: A Case Report and Review of the Literature". Diseases. 5 (4). doi:10.3390/diseases5040030. PMC 5750541. PMID 29292712.
  5. ↑ Miranda C, Jaker MA, Fitzhugh-Kull VA, Dever LL (2018). "Oropharyngeal histoplasmosis: The diagnosis lies in the biopsy". IDCases. 11: 33–35. doi:10.1016/j.idcr.2017.12.005. PMC 5738199. PMID 29276680.
  6. ↑ Jalisi S, Jamal BT, Grillone GA (2017). "Surgical Management of Long-standing Eagle's Syndrome". Ann Maxillofac Surg. 7 (2): 232–236. doi:10.4103/ams.ams_53_17. PMC 5717900. PMID 29264291.
  7. ↑ Jalisi S, Sakai O, Jamal BT, Mardirossian V (2017). "Features of Prevertebral Disease in Patients Presenting to a Head and Neck Surgery Clinic with Neck Pain". Ann Maxillofac Surg. 7 (2): 228–231. doi:10.4103/ams.ams_54_17. PMC 5717899. PMID 29264290.
  8. ↑ Marques S, Carmo J, Pinto D, Bispo M, Ramos S, Chagas C (2017). "Cytomegalovirus Disease of the Upper Gastrointestinal Tract: A 10-Year Retrospective Study". GE Port J Gastroenterol. 24 (6): 262–268. doi:10.1159/000479232. PMC 5731150. PMID 29255766.
  9. ↑ Rama-López J, Tomás-Fernandez M, García-Garza C, Martínez-Madrigal M (2018). "Pharyngeal perforation after anterior cervical spine surgery treated by transoral endoscopic surgery". Head Neck. 40 (2): E13–E16. doi:10.1002/hed.25030. PMID 29206327.
  10. ↑ Kato MG, Isaac MJ, Gillespie MB, O'Rourke AK (2018). "The Incidence and Characterization of Globus Sensation, Dysphagia, and Odynophagia Following Surgery for Obstructive Sleep Apnea". J Clin Sleep Med. 14 (1): 127–132. doi:10.5664/jcsm.6898. PMC 5734881. PMID 29198289.
  11. ↑ Teixeira C, Alves AL, Cremers I (2018). "Esophageal lichen planus: a rare case". Rev Esp Enferm Dig. 110 (1): 67–68. doi:10.17235/reed.2017.5332/2017. PMID 29168645.
  12. ↑ Chen L, Lai Y, Dong L, Kang S, Chen X (2017). "Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis". Microb Pathog. 113: 365–371. doi:10.1016/j.micpath.2017.11.018. PMID 29146495.
  13. ↑ Kim YJ, Park JY, Choi KY, Moon BJ, Lee JK (2017). "Case reports about an overlooked cause of neck pain: calcific tendinitis of the longus colli: Case reports". Medicine (Baltimore). 96 (46): e8343. doi:10.1097/MD.0000000000008343. PMC 5704790. PMID 29145245.
  14. ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  15. ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
  16. ↑ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002348/
  17. ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018671/
  18. ↑ http://www.ncbi.nlm.nih.gov/pubmed/6875362
  19. ↑ http://ghr.nlm.nih.gov/condition/mitochondrial-neurogastrointestinal-encephalopathy-disease
  20. ↑ http://www.ncbi.nlm.nih.gov/books/NBK1141/
  21. ↑ http://www.ncbi.nlm.nih.gov/books/NBK1523/

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