Small cell carcinoma of the lung laboratory tests: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
The following laboratory tests must be ordered in all patients with SCLC during the initial evaluation as well as during the assessment of response to treatment following the initial therapy:<ref name="NCCN">[http://www.nccn.org/professionals/physician_gls/f_guidelines_nojava.asp NCCN Clinical Practice Guidelines in Oncology. Small Cell Lung Cancer, version 2.2014] </ref> | The following laboratory tests must be ordered in all patients with SCLC during the initial evaluation as well as during the assessment of response to treatment following the initial therapy:<ref name="NCCN">[http://www.nccn.org/professionals/physician_gls/f_guidelines_nojava.asp NCCN Clinical Practice Guidelines in Oncology. Small Cell Lung Cancer, version 2.2014] </ref> | ||
* [[Complete blood count]] with differential | * [[Complete blood count]] with differential | ||
Revision as of 17:18, 23 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The initial evaluation of patients with small cell lung cancer (SCLC) confirmed by histopathological findings include a complete blood count with differential, electrolytes, liver function test, calcium level, LDH, BUN, and creatinine. These laboratory tests should also be performed to assess the response to the initial therapy.
Laboratory Findings
The following laboratory tests must be ordered in all patients with SCLC during the initial evaluation as well as during the assessment of response to treatment following the initial therapy:[1]
- Complete blood count with differential
- Low hemoglobin, thrombocytopenia, or leukopenia can be found if the metastatic cells infiltrated the bone marrow.
- Electrolytes
- Hyponatremia can be present if syndrome of inappropriate antidiuretic hormone secretion (SIADH) occurred as a complication of SCLC.
- Liver function test
- Liver function test should be done as a baseline and will be monitored during treatment. Liver enzymes can be elevated in metastasis.
- LDH
- Calcium level
- Hypercalcemia can be present in case of excessive production of parathyroid hormone as a paraneoplastic syndrome.
- BUN
- Creatinine