Cryptogenic organizing pneumonia other diagnostic studies

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Overview

Pulmonary function test may be helpful in the diagnosis of cryptogenic organizing pneumonia. Findings suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].

OR

Other diagnostic studies for [disease name] include [diagnostic study 1], which demonstrates [finding 1], [finding 2], and [finding 3], and [diagnostic study 2], which demonstrates [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

Pulmonary function test

• Pulmonary function test may be helpful in the diagnosis of cryptogenic organizing pneumonia.
• Findings suggestive of cryptogenic organizing pneumonia include:
  • The most common finding in cryptogenic organizing pneumonia is mild to moderate restrictive ventilatory defect.
  • In most of the cases, it shows an obstructive pattern(FEV1/FVC less than 70 percent).
  • DLCO is reduced.

Flexible bronchoscopy

• Flexible bronchoscopy is performed to obtain bronchoalveolar lavage sample (BAL) and transbronchial biopsy.

Bronchoalveolar Lavage

• BAL is done to know the etiology of cryptogenic organizing pneumonia.
• Various abnormal cells seen in cryptogenic organizing pneumonia are:
  • Foamy macrophages, mast cells, plasma cells.
  • A decreased CD4/CD8 T cell ratio.
  • An increase in activated T lymphocytes based on HLA-DR or interleukin-2 receptor expression.