Fat embolism syndrome historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
The historical perspective of fat embolism syndrome is as follows:<ref name="pmid4419160">{{cite journal| author=Allardyce DB, Meek RN, Woodruff B, Cassim MM, Ellis D| title=Increasing our knowledge of the pathogenesis of fat embolism: a prospective study of 43 patients with fractured femoral shafts. | journal=J Trauma | year= 1974 | volume= 14 | issue= 11 | pages= 955-62 | pmid=4419160 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4419160 }} </ref><ref name="pmid25328460">{{cite journal| author=Akoh CC, Schick C, Otero J, Karam M| title=Fat embolism syndrome after femur fracture fixation: a case report. | journal=Iowa Orthop J | year= 2014 | volume= 34 | issue= | pages= 55-62 | pmid=25328460 | doi= | pmc=4127739 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25328460 }} </ref> | The historical perspective of fat embolism syndrome is as follows:<ref name="pmid4419160">{{cite journal| author=Allardyce DB, Meek RN, Woodruff B, Cassim MM, Ellis D| title=Increasing our knowledge of the pathogenesis of fat embolism: a prospective study of 43 patients with fractured femoral shafts. | journal=J Trauma | year= 1974 | volume= 14 | issue= 11 | pages= 955-62 | pmid=4419160 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4419160 }} </ref><ref name="pmid25328460">{{cite journal| author=Akoh CC, Schick C, Otero J, Karam M| title=Fat embolism syndrome after femur fracture fixation: a case report. | journal=Iowa Orthop J | year= 2014 | volume= 34 | issue= | pages= 55-62 | pmid=25328460 | doi= | pmc=4127739 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25328460 }} </ref><ref name="KosovaBergmark2015">{{cite journal|last1=Kosova|first1=E.|last2=Bergmark|first2=B.|last3=Piazza|first3=G.|title=Fat Embolism Syndrome|journal=Circulation|volume=131|issue=3|year=2015|pages=317–320|issn=0009-7322|doi=10.1161/CIRCULATIONAHA.114.010835}}</ref> | ||
===Discovery=== | ===Discovery=== | ||
*In 1861, Zenker first discovered fat embolism (FES), after he found [[Lung|pulmonary]] [[capillary]] fat deposition in a patient who suffered from crush injury. | *In 1861, Zenker first discovered fat embolism (FES), after he found [[Lung|pulmonary]] [[capillary]] fat deposition in a patient who suffered from crush injury. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
In 1861, Zenker first discovered fat embolism (FES), after he found pulmonary capillary fat deposition in a patient who suffered from crush injury. In 1873, Bergmann described the first clinical case of FES in a patient who suffered a distal femur fracture. In 1875, Czerny explored cerebral symptoms associated with FES.
Historical Perspective
The historical perspective of fat embolism syndrome is as follows:[1][2][3]
Discovery
- In 1861, Zenker first discovered fat embolism (FES), after he found pulmonary capillary fat deposition in a patient who suffered from crush injury.
- In 1873, Bergmann described the first clinical case of FES in a patient who suffered a distal femur fracture.
- In 1875, Czerny explored cerebral symptoms associated with FES.
- In 1924, Gauss proposed the mechanical theory, which explains that three conditions are necessary for the development of fat embolism: injury to adipose tissue, rupture of veins within the zone of injury, and a mechanism that causes the passage of free fat into the open ends of blood vessel.
- In 1927, Lehman established biochemical theory which states that plasma mediators mobilize fat from body stores and cause the agglutination of bigger fat droplets and hence initiate an inflammatory process.
Landmark Events in the Development of Treatment Strategies
- In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
References
- ↑ Allardyce DB, Meek RN, Woodruff B, Cassim MM, Ellis D (1974). "Increasing our knowledge of the pathogenesis of fat embolism: a prospective study of 43 patients with fractured femoral shafts". J Trauma. 14 (11): 955–62. PMID 4419160.
- ↑ Akoh CC, Schick C, Otero J, Karam M (2014). "Fat embolism syndrome after femur fracture fixation: a case report". Iowa Orthop J. 34: 55–62. PMC 4127739. PMID 25328460.
- ↑ Kosova, E.; Bergmark, B.; Piazza, G. (2015). "Fat Embolism Syndrome". Circulation. 131 (3): 317–320. doi:10.1161/CIRCULATIONAHA.114.010835. ISSN 0009-7322.