Hypersensitivity pneumonitis natural history: Difference between revisions
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==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
=== Natural History === | === Natural History === | ||
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* Surgical lung biopsy can be done to check for fibrosis which is an indicator of poor prognosis.<ref name="pmid17641377">{{cite journal |vauthors=Sahin H, Brown KK, Curran-Everett D, Hale V, Cool CD, Vourlekis JS, Lynch DA |title=Chronic hypersensitivity pneumonitis: CT features comparison with pathologic evidence of fibrosis and survival |journal=Radiology |volume=244 |issue=2 |pages=591–8 |date=August 2007 |pmid=17641377 |doi=10.1148/radiol.2442060640 |url=}}</ref> | * Surgical lung biopsy can be done to check for fibrosis which is an indicator of poor prognosis.<ref name="pmid17641377">{{cite journal |vauthors=Sahin H, Brown KK, Curran-Everett D, Hale V, Cool CD, Vourlekis JS, Lynch DA |title=Chronic hypersensitivity pneumonitis: CT features comparison with pathologic evidence of fibrosis and survival |journal=Radiology |volume=244 |issue=2 |pages=591–8 |date=August 2007 |pmid=17641377 |doi=10.1148/radiol.2442060640 |url=}}</ref> | ||
* Prediction of prognosis can be done using high resolution CT scan.<ref name="pmid18403660">{{cite journal |vauthors=Hanak V, Golbin JM, Hartman TE, Ryu JH |title=High-resolution CT findings of parenchymal fibrosis correlate with prognosis in hypersensitivity pneumonitis |journal=Chest |volume=134 |issue=1 |pages=133–8 |date=July 2008 |pmid=18403660 |doi=10.1378/chest.07-3005 |url=}}</ref> | * Prediction of prognosis can be done using high resolution CT scan.<ref name="pmid18403660">{{cite journal |vauthors=Hanak V, Golbin JM, Hartman TE, Ryu JH |title=High-resolution CT findings of parenchymal fibrosis correlate with prognosis in hypersensitivity pneumonitis |journal=Chest |volume=134 |issue=1 |pages=133–8 |date=July 2008 |pmid=18403660 |doi=10.1378/chest.07-3005 |url=}}</ref> | ||
* A study done among old patients suffering from HP with no signs of air trapping on CT scan but desaturation with exercise showed poor survival rates.<ref name="pmid19179061">{{cite journal |vauthors=Lima MS, Coletta EN, Ferreira RG, Jasinowodolinski D, Arakaki JS, Rodrigues SC, Rocha NA, Pereira CA |title=Subacute and chronic hypersensitivity pneumonitis: histopathological patterns and survival |journal=Respir Med |volume=103 |issue=4 |pages=508–15 |date=April 2009 |pmid=19179061 |doi=10.1016/j.rmed.2008.12.016 |url=}}</ref> | * A study done among old patients suffering from HP with no signs of air trapping on CT scan but desaturation with exercise showed poor survival rates.<ref name="pmid19179061">{{cite journal |vauthors=Lima MS, Coletta EN, Ferreira RG, Jasinowodolinski D, Arakaki JS, Rodrigues SC, Rocha NA, Pereira CA |title=Subacute and chronic hypersensitivity pneumonitis: histopathological patterns and survival |journal=Respir Med |volume=103 |issue=4 |pages=508–15 |date=April 2009 |pmid=19179061 |doi=10.1016/j.rmed.2008.12.016 |url=}}</ref> | ||
==References== | ==References== |
Revision as of 15:54, 16 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of [disease name] include:
- [Complication 1]
- [Complication 2]
- [Complication 3]
Prognosis
- Prognosis of HP is generally excellent.
- Total lung recovery occurs in most cases but may take several years.[1]
- Surgical lung biopsy can be done to check for fibrosis which is an indicator of poor prognosis.[2]
- Prediction of prognosis can be done using high resolution CT scan.[3]
- A study done among old patients suffering from HP with no signs of air trapping on CT scan but desaturation with exercise showed poor survival rates.[4]
References
- ↑ Wang P, Xu ZJ, Xu WB, Shi JH, Tian XL, Feng RE, Zhu YJ (December 2009). "Clinical features and prognosis in 21 patients with extrinsic allergic alveolitis". Chin. Med. Sci. J. 24 (4): 202–7. PMID 20120765.
- ↑ Sahin H, Brown KK, Curran-Everett D, Hale V, Cool CD, Vourlekis JS, Lynch DA (August 2007). "Chronic hypersensitivity pneumonitis: CT features comparison with pathologic evidence of fibrosis and survival". Radiology. 244 (2): 591–8. doi:10.1148/radiol.2442060640. PMID 17641377.
- ↑ Hanak V, Golbin JM, Hartman TE, Ryu JH (July 2008). "High-resolution CT findings of parenchymal fibrosis correlate with prognosis in hypersensitivity pneumonitis". Chest. 134 (1): 133–8. doi:10.1378/chest.07-3005. PMID 18403660.
- ↑ Lima MS, Coletta EN, Ferreira RG, Jasinowodolinski D, Arakaki JS, Rodrigues SC, Rocha NA, Pereira CA (April 2009). "Subacute and chronic hypersensitivity pneumonitis: histopathological patterns and survival". Respir Med. 103 (4): 508–15. doi:10.1016/j.rmed.2008.12.016. PMID 19179061.