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| == Overview == | | == Overview == |
| Goodpasture syndrome must be differentiated from other diseases that cause rapid progressive glomerulonephritis and pulmonary hemorrhage. ANCA associated vasculitis, are disorders that affect the renal and pulmonary system, must be differentiated from Goodpasture syndrome.<ref name="pmid25462583">{{cite journal| author=Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G et al.| title=Goodpasture's syndrome: a clinical update. | journal=Autoimmun Rev | year= 2015 | volume= 14 | issue= 3 | pages= 246-53 | pmid=25462583 | doi=10.1016/j.autrev.2014.11.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25462583 }}</ref> | | Goodpasture syndrome should be differentiated from other diseases presenting as hemeturia and hemoptysis. It should also be differentiated from other causes of small vessel vasculitis. |
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| == Differential Diagnosis == | | == Differential Diagnosis == |
| Goodpasture syndrome must be differentiated from other diseases that cause rapid progressive glomerulonephritis and pulmonary hemorrhage. ANCA associated vasculitis, are disorders that affect the renal and pulmonary system, must be differentiated from Goodpasture syndrome.<ref name="pmid25462583">{{cite journal| author=Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G et al.| title=Goodpasture's syndrome: a clinical update. | journal=Autoimmun Rev | year= 2015 | volume= 14 | issue= 3 | pages= 246-53 | pmid=25462583 | doi=10.1016/j.autrev.2014.11.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25462583 }} </ref> | | Goodpasture syndrome should be differentiated from other diseases presenting as hemeturia and hemoptysis. It should also be differentiated from other causes of small vessel vasculitis. The differentials include the following: |
| ===Differentiating Goodpasture syndrome from Other Diseases===
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| Goodpasture syndrome must be differentiated from other diseases that cause rapid progressive glomerulonephritis and pulmonary hemorrhage, and include:<ref name="pmid25462583">{{cite journal| author=Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G et al.| title=Goodpasture's syndrome: a clinical update. | journal=Autoimmun Rev | year= 2015 | volume= 14 | issue= 3 | pages= 246-53 | pmid=25462583 | doi=10.1016/j.autrev.2014.11.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25462583 }} </ref>
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| * Granulomatosis with polyangiitis
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| * Eosinophilic granulomatosis with polyangiitis
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| * Microscopic polyangiitis
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| * Systemic lupus erythematosis
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| * Henoch-Schonlein purpura
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| * Microscopic polyarteritis
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| It is of extreme importance that Goodpasture syndrome be differentiated from Granulomatosis with polyangiitis as antineutrophil cytoplasmic antibodies can be seen in patients with Goodpasture syndrome.<ref name="pmid9355084">{{cite journal| author=Kalluri R, Meyers K, Mogyorosi A, Madaio MP, Neilson EG| title=Goodpasture syndrome involving overlap with Wegener's granulomatosis and anti-glomerular basement membrane disease. | journal=J Am Soc Nephrol | year= 1997 | volume= 8 | issue= 11 | pages= 1795-800 | pmid=9355084 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9355084 }} </ref>
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