Renal amyloidosis classification: Difference between revisions
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*Vascular amyloid deposition | *Vascular amyloid deposition | ||
*Tubular amyloid deposition | *Tubular amyloid deposition | ||
Renal amyloidosis may be classified according to type of amyloidogenic protein into 3 subtypes: | |||
* | |||
{| class="wikitable" | |||
! | |||
!Amyloidosis type | |||
!Amyloidogenic protein | |||
|- | |||
| rowspan="4" |Common types | |||
| rowspan="3" |AL/AHL/AH | |||
(Primary amyloidosis) | |||
|Ig light chains (AL) | |||
|- | |||
|Fragments of Ig heavy chains and light chains (AHL) | |||
|- | |||
|Fragments of heavy chains only (AH) | |||
|- | |||
|AA | |||
(Secondary amyloidosis) | |||
|Serum amyloid A | |||
|- | |||
| rowspan="6" |Rare types | |||
|AFib | |||
|Fibrinogen A α chain | |||
|- | |||
|AApo AI/AII/AIV | |||
|Apo AI, Apo AII, or Apo AIV | |||
|- | |||
|ATTR | |||
|Transthyretin | |||
|- | |||
|ALys | |||
|Lysozyme | |||
|- | |||
|AGel | |||
|Gelsolin | |||
|- | |||
|ALECT2 | |||
|Leukocyte chemotactic factor 2 | |||
|} | |||
==References== | ==References== |
Revision as of 23:27, 18 June 2018
Renal amyloidosis Microchapters |
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Template:Renal amyloidosis On the Web |
American Roentgen Ray Society Images of Renal amyloidosis classification |
Risk calculators and risk factors for Renal amyloidosis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
Classification
Renal amyloidosis may be classified according to site of amyloid deposition into 3 subtypes:[1]
- Glomerular amyloid deposition (more common and have a poorer prognosis)
- Vascular amyloid deposition
- Tubular amyloid deposition
Renal amyloidosis may be classified according to type of amyloidogenic protein into 3 subtypes:
Amyloidosis type | Amyloidogenic protein | |
---|---|---|
Common types | AL/AHL/AH
(Primary amyloidosis) |
Ig light chains (AL) |
Fragments of Ig heavy chains and light chains (AHL) | ||
Fragments of heavy chains only (AH) | ||
AA
(Secondary amyloidosis) |
Serum amyloid A | |
Rare types | AFib | Fibrinogen A α chain |
AApo AI/AII/AIV | Apo AI, Apo AII, or Apo AIV | |
ATTR | Transthyretin | |
ALys | Lysozyme | |
AGel | Gelsolin | |
ALECT2 | Leukocyte chemotactic factor 2 |
References
- ↑ Bilginer Y, Akpolat T, Ozen S (August 2011). "Renal amyloidosis in children". Pediatr. Nephrol. 26 (8): 1215–27. doi:10.1007/s00467-011-1797-x. PMC 3119800. PMID 21360109.