Fanconi anemia other diagnostic studies: Difference between revisions
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=== Fetal hemoglobin study === | |||
Fetal hemoglobin (HbF) may be increased for age as a manifestation of stress erythropoiesis. | |||
=== Adenosine deaminase study === | |||
Red cell adenosine deaminase (ADA) is increased in approximately 85% of patients with Diamond-Blackfan anemia (DBA) but appears to be normal in Fanconi anemia. | |||
=== Serum erythropoietin study === | |||
Serum erythropoietin (Ep) levels are markedly increased and higher than expected for the degree of anemia, similar to that observed in DBA. However, levels may be low in patients with impaired renal function. | |||
==References== | ==References== | ||
Revision as of 15:06, 25 June 2018
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Fetal hemoglobin study
Fetal hemoglobin (HbF) may be increased for age as a manifestation of stress erythropoiesis.
Adenosine deaminase study
Red cell adenosine deaminase (ADA) is increased in approximately 85% of patients with Diamond-Blackfan anemia (DBA) but appears to be normal in Fanconi anemia.
Serum erythropoietin study
Serum erythropoietin (Ep) levels are markedly increased and higher than expected for the degree of anemia, similar to that observed in DBA. However, levels may be low in patients with impaired renal function.