Hemophilia A risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Risk factors for development of [[Hemophilia A]] include being of male sex and having a positive [[family history]] of the disease. | Risk factors for development of [[Hemophilia A]] include being of male sex and having a positive [[family history]] of the disease. | ||
It is of note that acquired forms of the disease occur in specific circumstances including Malignancies, Pregnancy, Autoimmune disorders, Certain medications; All of which could be considered as Hemophilia risk factor either. | |||
==Risk Factors== | ==Risk Factors== | ||
Common risk factors in the development of Hemophilia A are: | Common risk factors in the development of Hemophilia A are: | ||
*Male sex | *Male sex | ||
*Family history of [[bleeding]]<ref> How Hemophilia is Inherited | Hemophilia | NCBDDD | CDC. Available at http://www.cdc.gov/ncbddd/hemophilia/inheritance-pattern.html. Accessed on Sept 20, 2016 </ref> | *Family history of [[bleeding]]<ref>How Hemophilia is Inherited | Hemophilia | NCBDDD | CDC. Available at http://www.cdc.gov/ncbddd/hemophilia/inheritance-pattern.html. Accessed on Sept 20, 2016 </ref> | ||
Best-studied risk factors of the acquired form of the disease include: | |||
* Malignancies (mostly hematologic) | |||
* Pregnancy | |||
* Autoimmune disorders(Lupus erythematosus, Rheumatoid arthritis) | |||
* Infections(Hepatitis C, AIDS) | |||
* Certain Drugs consumption (e.g. Interferon-ą) | |||
* Dermatological conditions(Pemphigus, Psoriasis) | |||
Of note, the majority of reported acquired cases of Hemophilia are about Hemophilia A type. It appears that, the same as congenital form, acquired form of Hemophilia B is rarer than Hemophilia A too. | |||
The remaining cases of acquired Hemophilia are idiopathic or the underlying etiology is not known yet. | |||
==References== | ==References== |
Revision as of 14:04, 14 July 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fahd Yunus, M.D. [2]
Overview
Risk factors for development of Hemophilia A include being of male sex and having a positive family history of the disease.
It is of note that acquired forms of the disease occur in specific circumstances including Malignancies, Pregnancy, Autoimmune disorders, Certain medications; All of which could be considered as Hemophilia risk factor either.
Risk Factors
Common risk factors in the development of Hemophilia A are:
Best-studied risk factors of the acquired form of the disease include:
- Malignancies (mostly hematologic)
- Pregnancy
- Autoimmune disorders(Lupus erythematosus, Rheumatoid arthritis)
- Infections(Hepatitis C, AIDS)
- Certain Drugs consumption (e.g. Interferon-ą)
- Dermatological conditions(Pemphigus, Psoriasis)
Of note, the majority of reported acquired cases of Hemophilia are about Hemophilia A type. It appears that, the same as congenital form, acquired form of Hemophilia B is rarer than Hemophilia A too.
The remaining cases of acquired Hemophilia are idiopathic or the underlying etiology is not known yet.
References
- ↑ How Hemophilia is Inherited | Hemophilia | NCBDDD | CDC. Available at http://www.cdc.gov/ncbddd/hemophilia/inheritance-pattern.html. Accessed on Sept 20, 2016