Monoclonal gammopathy of undetermined significance historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
===Discovery=== | ===Discovery=== | ||
*Monoclonal gammopathy of undetermined significance was first discivered by Jan G. Waldenstrom in 1960 “essential hyperglobulinemia” or “benign monoclonal gammopathy” and then as monoclonal gammopathy of undetermined significance by Robert A. Kyle in 1978. <ref name="pmid14004528">{{cite journal |vauthors=WALDENSTROM J |title=Studies on conditions associated with disturbed gamma globulin formation (gammopathies) |journal=Harvey Lect. |volume=56 |issue= |pages=211–31 |date=1960 |pmid=14004528 |doi= |url=}}</ref> | *Monoclonal gammopathy of undetermined significance was first discivered by Jan G. Waldenstrom in 1960 “essential hyperglobulinemia” or “benign monoclonal gammopathy” and then as monoclonal gammopathy of undetermined significance by Robert A. Kyle in 1978. <ref name="pmid14004528">{{cite journal |vauthors=WALDENSTROM J |title=Studies on conditions associated with disturbed gamma globulin formation (gammopathies) |journal=Harvey Lect. |volume=56 |issue= |pages=211–31 |date=1960 |pmid=14004528 |doi= |url=}}</ref> Introduced more than 35 years ago, the term monoclonal gammopathy of undetermined signficance was used because of the increased risk of patients for the development of symptomatic MM, WM, Light-chain (AL) amyloidosis, or a related disorder during long-term follow-up.<ref name="pmid15244381">{{cite journal |vauthors=Kyle RA, Therneau TM, Rajkumar SV, Larson DR, Plevak MF, Melton LJ |title=Long-term follow-up of 241 patients with monoclonal gammopathy of undetermined significance: the original Mayo Clinic series 25 years later |journal=Mayo Clin. Proc. |volume=79 |issue=7 |pages=859–66 |date=July 2004 |pmid=15244381 |doi=10.1016/S0025-6196(11)62151-4 |url=}}</ref> | ||
==Outbreaks== | ==Outbreaks== | ||
There have been several outbreaks of [disease name], which are summarized below: | There have been several outbreaks of [disease name], which are summarized below: | ||
Revision as of 16:39, 14 August 2018
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Monoclonal gammopathy of undetermined significance Microchapters |
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Differentiating Monoclonal gammopathy of undetermined significance from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
Discovery
- Monoclonal gammopathy of undetermined significance was first discivered by Jan G. Waldenstrom in 1960 “essential hyperglobulinemia” or “benign monoclonal gammopathy” and then as monoclonal gammopathy of undetermined significance by Robert A. Kyle in 1978. [1] Introduced more than 35 years ago, the term monoclonal gammopathy of undetermined signficance was used because of the increased risk of patients for the development of symptomatic MM, WM, Light-chain (AL) amyloidosis, or a related disorder during long-term follow-up.[2]
Outbreaks
There have been several outbreaks of [disease name], which are summarized below:
Landmark Events in the Development of Treatment Strategies
In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
Impact on Cultural History
Famous Cases
The following are a few famous cases of disease name:
References
- ↑ WALDENSTROM J (1960). "Studies on conditions associated with disturbed gamma globulin formation (gammopathies)". Harvey Lect. 56: 211–31. PMID 14004528.
- ↑ Kyle RA, Therneau TM, Rajkumar SV, Larson DR, Plevak MF, Melton LJ (July 2004). "Long-term follow-up of 241 patients with monoclonal gammopathy of undetermined significance: the original Mayo Clinic series 25 years later". Mayo Clin. Proc. 79 (7): 859–66. doi:10.1016/S0025-6196(11)62151-4. PMID 15244381.