Aplastic anemia pathophysiology: Difference between revisions

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Revision as of 14:22, 15 August 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2] Nazia Fuad M.D.

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 {{Aplastic anemia}}
-{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh13579@gmail.com]
+{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh13579@gmail.com]  {{N.F}}
 Please help WikiDoc by adding content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
 ==Overview==
-[[Aplastic anemia]] is a fatal disorder in which bone marrow's myeloid progenitor cells and [[stem cell]]s are severely decreased or absent. This may be seen because of either an intrinsic defect of the stem cells or immune-mediated stem cell destruction. As a result of hypocellular stem cells, transfusion-dependent anemia, [[thrombocytopenia]], and severe [[neutropenia]] are seen with [[aplastic anemia]]. [[Interferon]]-activated T lymphocytes are involved in [[autoimmune]] destruction of [[stem cell]]s in both forms of the disease i.e. idiopathic and the acquired. Due to this, immunosuppressive therapy is effective in some patients.
 ==Pathophysiology==
+{| align="right"
+|[[File:Aplasticanemia.jpg |400px|thumb|right|Image yellow fat ladden marrow https://www.wikidoc.org/index.php/File:Aplasticanemia.jpg source:By Wmheric [CC BY-SA 3.0  (https://creativecommons.org/licenses/by-sa/3.0)] [Public domain], from Wikimedia Commons]]]
+|}
 ==References==