Aplastic anemia classification: Difference between revisions
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==Classification== | ==Classification== | ||
Aplastic anemia may be classified according to blood cell counts into 3 subgroups:<ref name="pmid24424170">{{cite journal |vauthors=Dolberg OJ, Levy Y |title=Idiopathic aplastic anemia: diagnosis and classification |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=569–73 |date=2014 |pmid=24424170 |doi=10.1016/j.autrev.2014.01.014 |url=}}</ref> | Aplastic anemia may be classified according to blood cell counts into 3 subgroups:<ref name="pmid24424170">{{cite journal |vauthors=Dolberg OJ, Levy Y |title=Idiopathic aplastic anemia: diagnosis and classification |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=569–73 |date=2014 |pmid=24424170 |doi=10.1016/j.autrev.2014.01.014 |url=}}</ref> | ||
* Moderately severe aplastic anemia or non severe AA (nSAA) | |||
* Severe aplastic anemia (SAA) | |||
* Very severe aplastic anemia(vSAA) | |||
{| class="wikitable" | {| class="wikitable" | ||
|+ '''Classification of aplastic anemia (two out of three criteria must be met)''' | |+ '''Classification of aplastic anemia (two out of three criteria must be met)''' | ||
Revision as of 18:59, 20 August 2018
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Aplastic anemia classification On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2] Nazia Fuad M.D.
Overview
Aplastic anemia may be classified according to blood cell counts into 3 subgroups, moderately severe aplastic anemia or non severe AA (nSAA), severe aplastic anemia (SAA), and very severe aplastic anemia(vSAA).
Classification
Aplastic anemia may be classified according to blood cell counts into 3 subgroups:[1]
- Moderately severe aplastic anemia or non severe AA (nSAA)
- Severe aplastic anemia (SAA)
- Very severe aplastic anemia(vSAA)
| nSAA | SAA | vSAA | |
|---|---|---|---|
| Reticulocytes | <20G/L | <20G/L | <20G/L |
| Platelets | <50 G / L | <20G/L | <20G/L |
| Neutrophilic granulocytes | <1.0 G / L | <0.5G/L | 0.2G/L |
This classification is of prognostic relevance and has an influence on therapeutic procedures.
| Acquired aplastic anemia | |
|---|---|
| Idiopathic | |
| Secondry | Irradiation
Drugs and chemicals: cytotoxic agents, benzene, chloromphenicol, gold salts, NSAIDS Idiosyncratic reactions Viruses: Epstein Barr virus, parvovirus B19, HIV Immune diseases |
| Inherited aplastic anemia | Fanconi anemia |
References
- ↑ Dolberg OJ, Levy Y (2014). "Idiopathic aplastic anemia: diagnosis and classification". Autoimmun Rev. 13 (4–5): 569–73. doi:10.1016/j.autrev.2014.01.014. PMID 24424170.