Breast lumps causes: Difference between revisions
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===Common Causes In Male=== | ===Common Causes In Male=== | ||
Breast enlargement in male adolescents is defined as [[gynecomastia]]. Common causes of breast lumps in male include:<ref name="pmid9360527">{{cite journal| author=Ormandy CJ, Hall RE, Manning DL, Robertson JF, Blamey RW, Kelly PA et al.| title=Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in breast cancer. | journal=J Clin Endocrinol Metab | year= 1997 | volume= 82 | issue= 11 | pages= 3692-9 | pmid=9360527 | doi=10.1210/jcem.82.11.4361 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9360527 }}</ref><ref name="pmid20008419">{{cite journal| author=Durmaz E, Ozmert EN, Erkekoglu P, Giray B, Derman O, Hincal F et al.| title=Plasma phthalate levels in pubertal gynecomastia. | journal=Pediatrics | year= 2010 | volume= 125 | issue= 1 | pages= e122-9 | pmid=20008419 | doi=10.1542/peds.2009-0724 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20008419 }}</ref><ref name="pmid178817542">{{cite journal| author=Braunstein GD| title=Clinical practice. Gynecomastia. | journal=N Engl J Med | year= 2007 | volume= 357 | issue= 12 | pages= 1229-37 | pmid=17881754 | doi=10.1056/NEJMcp070677 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17881754 }}</ref><ref>Swerdloff RS, Ng JCM. Gynecomastia: Etiology, Diagnosis, and Treatment. [Updated 2015 Aug 3]. In: De Groot LJ, Chrousos G, Dungan K, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279105/</ref> | Breast enlargement in male adolescents is defined as [[gynecomastia]]. Common causes of breast lumps in male include:<ref name="pmid9360527">{{cite journal| author=Ormandy CJ, Hall RE, Manning DL, Robertson JF, Blamey RW, Kelly PA et al.| title=Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in breast cancer. | journal=J Clin Endocrinol Metab | year= 1997 | volume= 82 | issue= 11 | pages= 3692-9 | pmid=9360527 | doi=10.1210/jcem.82.11.4361 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9360527 }}</ref><ref name="pmid20008419">{{cite journal| author=Durmaz E, Ozmert EN, Erkekoglu P, Giray B, Derman O, Hincal F et al.| title=Plasma phthalate levels in pubertal gynecomastia. | journal=Pediatrics | year= 2010 | volume= 125 | issue= 1 | pages= e122-9 | pmid=20008419 | doi=10.1542/peds.2009-0724 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20008419 }}</ref><ref name="pmid178817542">{{cite journal| author=Braunstein GD| title=Clinical practice. Gynecomastia. | journal=N Engl J Med | year= 2007 | volume= 357 | issue= 12 | pages= 1229-37 | pmid=17881754 | doi=10.1056/NEJMcp070677 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17881754 }}</ref><ref name=":1">Swerdloff RS, Ng JCM. Gynecomastia: Etiology, Diagnosis, and Treatment. [Updated 2015 Aug 3]. In: De Groot LJ, Chrousos G, Dungan K, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279105/</ref> | ||
*[[Adipose tissue]] | *[[Adipose tissue]] | ||
*[[Aging]]- more common in older men as male hormones reduce. | *[[Aging]]- more common in older men as male hormones reduce. | ||
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| '''Endocrine''' | | '''Endocrine'''<ref name="pmid11732643">{{cite journal| author=Ismail AA, Barth JH| title=Endocrinology of gynaecomastia. | journal=Ann Clin Biochem | year= 2001 | volume= 38 | issue= Pt 6 | pages= 596-607 | pmid=11732643 | doi=10.1258/0004563011900993 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11732643 }}</ref> | ||
| bgcolor="Beige" | [[17-beta-hydroxysteroid dehydrogenase deficiency ]] , [[Androgen insensitivity syndrome ]] , Brugschs syndrome, Camera-marugo-cohen syndrome, Cantalamessa-baldini-ambrosi syndrome, [[Congenital adrenal hyperplasia]] 17-alpha-hydroxylase deficiency, [[Congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency|3-beta-hydroxysteroid dehydrogenase deficiency]], [[Empty sella syndrome ]] , [[Feminization]], [[Forbes-Albright syndrome]] , [[Gonadotropin-releasing hormone deficiency|luteinizing hormone releasing hormone deficiency]], [[Gynecomastia]], H syndrome, [[Hanhart syndrome]], Heller-nelson syndrome, [[Hormone replacement therapy]], [[Hyperprolactinemia]], [[Klinefelter syndrome]], [[Lactotroph adenoma]], Newborn infant breast swelling, Obal syndrome, [[Partial androgen insensitivity]], [[Primrose syndrome]], [[Pseudohermaphroditism|pseudohermaphroditism male]],[[Puberty]], Salvioli syndrome, [[Sohval-Soffer syndrome]], [[Summitt syndrome]], [[Tang Hsi Ryu syndrome]], [[Vasquez Hurst Sotos syndrome]], [[Wilson-Turner X-linked mental retardation syndrome|Wilson turner syndrome]], [[XX male syndrome]], [[XX male syndrome|de la chapelle syndrome]] | | bgcolor="Beige" | [[17-beta-hydroxysteroid dehydrogenase deficiency ]] , [[Androgen insensitivity syndrome ]] , Brugschs syndrome, Camera-marugo-cohen syndrome, Cantalamessa-baldini-ambrosi syndrome, [[Congenital adrenal hyperplasia]] 17-alpha-hydroxylase deficiency, [[Congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency|3-beta-hydroxysteroid dehydrogenase deficiency]], [[Empty sella syndrome ]] , [[Feminization]], [[Forbes-Albright syndrome]] , [[Gonadotropin-releasing hormone deficiency|luteinizing hormone releasing hormone deficiency]], [[Gynecomastia]], H syndrome, [[Hanhart syndrome]], Heller-nelson syndrome, [[Hormone replacement therapy]], [[Hyperprolactinemia]], [[Klinefelter syndrome]], [[Lactotroph adenoma]], Newborn infant breast swelling, Obal syndrome, [[Partial androgen insensitivity]], [[Primrose syndrome]], [[Pseudohermaphroditism|pseudohermaphroditism male]],[[Puberty]], Salvioli syndrome, [[Sohval-Soffer syndrome]], [[Summitt syndrome]], [[Tang Hsi Ryu syndrome]], [[Vasquez Hurst Sotos syndrome]], [[Wilson-Turner X-linked mental retardation syndrome|Wilson turner syndrome]], [[XX male syndrome]], [[XX male syndrome|de la chapelle syndrome]] | ||
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| '''Genetic''' | | '''Genetic<ref name=":1" />''' | ||
| bgcolor="Beige" | [[17-beta-hydroxysteroid dehydrogenase deficiency]], 46,XX testicular disorder of sex development, [[Androgen insensitivity syndrome ]] , Brugschs syndrome, [[Congenital adrenal hyperplasia]] 17-alpha-hydroxylase deficiency, [[Congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency|3-beta-hydroxysteroid dehydrogenase deficiency]], [[Fragile X syndrome]], [[Klinefelter syndrome]], [[Lesch-Nyhan's syndrome]], Obal syndrome, [[Summitt syndrome]], [[Tang Hsi Ryu syndrome]], [[Vasquez Hurst Sotos syndrome]], [[XX male syndrome]], [[XX male syndrome|de la chapelle syndrome]] | | bgcolor="Beige" | [[17-beta-hydroxysteroid dehydrogenase deficiency]], 46,XX testicular disorder of sex development, [[Androgen insensitivity syndrome ]] , Brugschs syndrome, [[Congenital adrenal hyperplasia]] 17-alpha-hydroxylase deficiency, [[Congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency|3-beta-hydroxysteroid dehydrogenase deficiency]], [[Fragile X syndrome]], [[Klinefelter syndrome]], [[Lesch-Nyhan's syndrome]], Obal syndrome, [[Summitt syndrome]], [[Tang Hsi Ryu syndrome]], [[Vasquez Hurst Sotos syndrome]], [[XX male syndrome]], [[XX male syndrome|de la chapelle syndrome]] | ||
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Revision as of 14:10, 4 January 2019
Breast lumps Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Breast lumps causes On the Web |
American Roentgen Ray Society Images of Breast lumps causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jyostna Chouturi, M.B.B.S [2], João André Alves Silva, M.D. [3], Shadan Mehraban, M.D.[4]
Overview
Causes In Female
Life Threatening Causes
There are no life-threatening causes.[1]
Common Causes In Female
The most common causes of breast lumps in females are:[1][2]
- Benign inflammatory periductal mastitis
- Breast abscess
- Breast cancer
- Breast adenoma
- Breast trauma
- Cysts of Montgomery
- Duct ectasia of breast
- Estrogen and progestin
- Etonogestrel and ethinyl estradiol
- Fibro-adeno-lipoma
- Galactocele
- Glandular thickening due to hormonal changes of pregnancy
- Gynecomastia
- Hematoma
- Hypertrophy
- Intramammary lymph node
- Lipoma
- Premenstrual syndrome
- Progestin
- Retroareolar cyst
- Simple cyst
Causes In Female by Organ System
Causes In Female In Alphabetical Order
The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3Causes In Males
Life-Threatening Causes
There are no life-threatening causes.
Common Causes In Male
Breast enlargement in male adolescents is defined as gynecomastia. Common causes of breast lumps in male include:[3][4][5][6]
- Adipose tissue
- Aging- more common in older men as male hormones reduce.
- Breast abscess
- Breast cancer
- Hepatoma
- Hyperthyroidism
- Hypogonadism
- Metastatic cancer
- Neurofibroma
- XXY males
Causes in Male by Organ System
Cardiovascular | Cantalamessa-baldini-ambrosi syndrome |
Chemical/Poisoning | No underlying causes |
Dental | No underlying causes |
Dermatologic | Cantalamessa-baldini-ambrosi syndrome, gingival fibromatosis hypertrichosis, H syndrome, Pachydermoperiostosis , |
Drug Side Effect | Aldactone, bicalutamide, chloropromazine, cimetidine, flutamide, itraconazole, metoclopramide, nizoral |
Ear Nose Throat | Gingival fibromatosis hypertrichosis, H syndrome, Retinitis pigmentosa, deafness, mental retardation, hypogonadism- syndrome |
Endocrine[7] | 17-beta-hydroxysteroid dehydrogenase deficiency , Androgen insensitivity syndrome , Brugschs syndrome, Camera-marugo-cohen syndrome, Cantalamessa-baldini-ambrosi syndrome, Congenital adrenal hyperplasia 17-alpha-hydroxylase deficiency, 3-beta-hydroxysteroid dehydrogenase deficiency, Empty sella syndrome , Feminization, Forbes-Albright syndrome , luteinizing hormone releasing hormone deficiency, Gynecomastia, H syndrome, Hanhart syndrome, Heller-nelson syndrome, Hormone replacement therapy, Hyperprolactinemia, Klinefelter syndrome, Lactotroph adenoma, Newborn infant breast swelling, Obal syndrome, Partial androgen insensitivity, Primrose syndrome, pseudohermaphroditism male,Puberty, Salvioli syndrome, Sohval-Soffer syndrome, Summitt syndrome, Tang Hsi Ryu syndrome, Vasquez Hurst Sotos syndrome, Wilson turner syndrome, XX male syndrome, de la chapelle syndrome |
Environmental | No underlying causes |
Gastroenterologic | Cirrhosis of the liver, Hepatocellular carcinoma (fibrolamellar variant), Peutz-Jeghers syndrome, Tang Hsi Ryu syndrome |
Genetic[6] | 17-beta-hydroxysteroid dehydrogenase deficiency, 46,XX testicular disorder of sex development, Androgen insensitivity syndrome , Brugschs syndrome, Congenital adrenal hyperplasia 17-alpha-hydroxylase deficiency, 3-beta-hydroxysteroid dehydrogenase deficiency, Fragile X syndrome, Klinefelter syndrome, Lesch-Nyhan's syndrome, Obal syndrome, Summitt syndrome, Tang Hsi Ryu syndrome, Vasquez Hurst Sotos syndrome, XX male syndrome, de la chapelle syndrome |
Hematologic | No underlying causes |
Iatrogenic | No underlying causes |
Infectious Disease | Lymphatic filariasis, |
Musculoskeletal/Orthopedic | Brugschs syndrome, Camera-marugo-cohen syndrome, Lesch-Nyhan's syndrome, Salvioli syndrome, Sohval-Soffer syndrome,Summitt syndrome |
Neurologic | Camera-marugo-cohen syndrome, Fragile X syndrome,progressive spinobulbar muscular atrophy, Retinitis pigmentosa, deafness, mental retardation, hypogonadism, Sohval-Soffer syndrome, Spinal muscular atrophy, Summitt syndrome, Tang Hsi Ryu syndrome, Vasquez Hurst Sotos syndrome, wilson turner syndrome, |
Nutritional/Metabolic | No underlying causes |
Obstetric/Gynecologic | No underlying causes |
Oncologic | Breast cancer |
Ophthalmologic | Cantalamessa-baldini-ambrosi syndrome, Obal syndrome, Retinitis pigmentosa, deafness, mental retardation, hypogonadism. |
Overdose/Toxicity | No underlying causes |
Psychiatric | sexual arousal |
Pulmonary | No underlying causes |
Renal/Electrolyte | No underlying causes |
Rheumatology/Immunology/Allergy | No underlying causes |
Sexual | sexual arousal |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | No underlying causes |
Causes in Male in Alphabetical order
The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3Causes in Children
- Neonates and infants [8]
- Breast hypertrophy due to maternal hormones
- Prepubertal and pubertal children[9][10]
- Breast infection
- Hemangiomas and lymphangiomas
- Lipomastia
- Premature Thelarche and Thelarche
- Trauma
Causes in Male Adolescents
- Breast enlargement in male adolescents is defined as gynecomastia:[11]
Causes in Female Adolescents
- Fibrocystic change[13]
- Juvenille fibroadenoma[14]
- Giant fibroadenoma[8]
- Phyllodes tumor[15][16]
- Mammary duct ectasia[17]
- Cysts of montgomery[10]
References
- ↑ 1.0 1.1 Santen RJ. Benign Breast Disease in Women. [Updated 2018 May 25]. In: De Groot LJ, Chrousos G, Dungan K, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK278994/
- ↑ Rohan TE, Negassa A, Chlebowski RT, Lasser NL, McTiernan A, Schenken RS; et al. (2008). "Estrogen plus progestin and risk of benign proliferative breast disease". Cancer Epidemiol Biomarkers Prev. 17 (9): 2337–43. doi:10.1158/1055-9965.EPI-08-0380. PMC 2584343. PMID 18725513.
- ↑ Ormandy CJ, Hall RE, Manning DL, Robertson JF, Blamey RW, Kelly PA; et al. (1997). "Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in breast cancer". J Clin Endocrinol Metab. 82 (11): 3692–9. doi:10.1210/jcem.82.11.4361. PMID 9360527.
- ↑ Durmaz E, Ozmert EN, Erkekoglu P, Giray B, Derman O, Hincal F; et al. (2010). "Plasma phthalate levels in pubertal gynecomastia". Pediatrics. 125 (1): e122–9. doi:10.1542/peds.2009-0724. PMID 20008419.
- ↑ Braunstein GD (2007). "Clinical practice. Gynecomastia". N Engl J Med. 357 (12): 1229–37. doi:10.1056/NEJMcp070677. PMID 17881754.
- ↑ 6.0 6.1 Swerdloff RS, Ng JCM. Gynecomastia: Etiology, Diagnosis, and Treatment. [Updated 2015 Aug 3]. In: De Groot LJ, Chrousos G, Dungan K, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279105/
- ↑ Ismail AA, Barth JH (2001). "Endocrinology of gynaecomastia". Ann Clin Biochem. 38 (Pt 6): 596–607. doi:10.1258/0004563011900993. PMID 11732643.
- ↑ 8.0 8.1 Greydanus DE, Matytsina L, Gains M (2006). "Breast disorders in children and adolescents". Prim Care. 33 (2): 455–502. doi:10.1016/j.pop.2006.02.002. PMID 16713771.
- ↑ Kaplowitz P, Bloch C, Section on Endocrinology, American Academy of Pediatrics (2016). "Evaluation and Referral of Children With Signs of Early Puberty". Pediatrics. 137 (1). doi:10.1542/peds.2015-3732. PMID 26668298.
- ↑ 10.0 10.1 De Silva NK, Brandt ML (2006). "Disorders of the breast in children and adolescents, Part 2: breast masses". J Pediatr Adolesc Gynecol. 19 (6): 415–8. doi:10.1016/j.jpag.2006.09.002. PMID 17174833.
- ↑ Braunstein GD (2007). "Clinical practice. Gynecomastia". N Engl J Med. 357 (12): 1229–37. doi:10.1056/NEJMcp070677. PMID 17881754.
- ↑ Deepinder F, Braunstein GD (2012). "Drug-induced gynecomastia: an evidence-based review". Expert Opin Drug Saf. 11 (5): 779–95. doi:10.1517/14740338.2012.712109. PMID 22862307.
- ↑ Templeman C, Hertweck SP (2000). "Breast disorders in the pediatric and adolescent patient". Obstet Gynecol Clin North Am. 27 (1): 19–34. PMID 10693180.
- ↑ Sanders LM, Sharma P, El Madany M, King AB, Goodman KS, Sanders AE (2018). "Clinical breast concerns in low-risk pediatric patients: practice review with proposed recommendations". Pediatr Radiol. 48 (2): 186–195. doi:10.1007/s00247-017-4007-6. PMID 29080125.
- ↑ Parker SJ, Harries SA (2001). "Phyllodes tumours". Postgrad Med J. 77 (909): 428–35. PMC 1760996. PMID 11423590.
- ↑ Pistolese CA, Tanga I, Cossu E, Perretta T, Yamgoue M, Bonanno E; et al. (2009). "A phyllodes tumor in a child". J Pediatr Adolesc Gynecol. 22 (3): e21–4. doi:10.1016/j.jpag.2007.11.006. PMID 19539191.
- ↑ Schwartz GF (1982). "Benign neoplasms and "inflammations" of the breast". Clin Obstet Gynecol. 25 (2): 373–85. PMID 6286199.