The '''Glycine receptor subunit alpha-3''' is a [[protein]] that in humans is encoded by the ''GLRA3'' [[gene]].<ref name="pmid9677400">{{cite journal |vauthors=Nikolic Z, Laube B, Weber RG, Lichter P, Kioschis P, Poustka A, Mulhardt C, Becker CM | title = The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts | journal = J Biol Chem | volume = 273 | issue = 31 | pages = 19708–14 |date=Sep 1998 | pmid = 9677400 | pmc = | doi =10.1074/jbc.273.31.19708 }}</ref> The [[protein]] encoded by this gene is a subunit of the [[glycine receptor]].<ref name="pmid9677400" />
The '''Glycine receptor subunit alpha-3''' is a [[protein]] that in humans is encoded by the ''GLRA3'' [[gene]].<ref name="pmid9677400">{{cite journal |vauthors=Nikolic Z, Laube B, Weber RG, Lichter P, Kioschis P, Poustka A, Mulhardt C, Becker CM | title = The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts | journal = J Biol Chem | volume = 273 | issue = 31 | pages = 19708–14 |date=Sep 1998 | pmid = 9677400 | pmc = | doi =10.1074/jbc.273.31.19708 }}</ref> The [[protein]] encoded by this gene is a subunit of the [[glycine receptor]].<ref name="pmid9677400" />
Variants of this receptor subunit is associated with susceptibility to [[epilepsy]].<ref name="pmid11496371">{{cite journal |vauthors=Sobetzko D, Sander T, Becker CM | title = Genetic variation of the human glycine receptor subunit genes GLRA3 and GLRB and susceptibility to idiopathic generalized epilepsies | journal = Am. J. Med. Genet. | volume = 105 | issue = 6 | pages = 534–8 |date=August 2001 | pmid = 11496371 | doi = 10.1002/ajmg.1488 | url = }}</ref>
The Glycine receptor subunit alpha-3 is a protein that in humans is encoded by the GLRA3gene.[1] The protein encoded by this gene is a subunit of the glycine receptor.[1]
References
↑ 1.01.1Nikolic Z, Laube B, Weber RG, Lichter P, Kioschis P, Poustka A, Mulhardt C, Becker CM (Sep 1998). "The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts". J Biol Chem. 273 (31): 19708–14. doi:10.1074/jbc.273.31.19708. PMID9677400.
Further reading
Breitinger HG, Villmann C, Rennert J, et al. (2002). "Hydroxylated residues influence desensitization behaviour of recombinant alpha3 glycine receptor channels". J. Neurochem. 83 (1): 30–6. doi:10.1046/j.1471-4159.2002.01109.x. PMID12358726.
Gratacòs M, Costas J, de Cid R, et al. (2009). "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment". Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6): 808–16. doi:10.1002/ajmg.b.30902. PMID19086053.
