Small intestine cancer medical therapy: Difference between revisions
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{{CMG}}{{AE}}{{Qurrat}} {{PSD}} | {{CMG}}{{AE}}{{Qurrat}} {{PSD}} | ||
==Overview== | ==Overview== | ||
Best treatment for curable small intestine cancer is surgical resection with combination of chemotherapy or radiotherapy. If tumor is not curable palliative surgery can be done.[[Chemotherapy]] is used to reduce the likelihood of metastasis developing, shrink tumor size, and slow tumor growth. [[Chemotherapy]] is often applied after [[surgery]] ([[adjuvant]]), before surgery ([[Neoadjuvant chemotherapy|neo-adjuvant]]), or as primary therapy if surgery is not indicated ([[Palliative care|palliative]]). Other therapies include [[Radiation therapy|radiation]] and support therapies. | Best treatment for curable [[small intestine]] cancer is surgical resection with combination of [[chemotherapy]] or [[radiotherapy]]. If tumor is not curable [[Palliative therapy|palliative surgery]] can be done.[[Chemotherapy]] is used to reduce the likelihood of [[metastasis]] developing, shrink tumor size, and slow tumor growth. [[Chemotherapy]] is often applied after [[surgery]] ([[adjuvant]]), before surgery ([[Neoadjuvant chemotherapy|neo-adjuvant]]), or as primary therapy if surgery is not indicated ([[Palliative care|palliative]]). Other therapies include [[Radiation therapy|radiation]] and support therapies. | ||
==Treatment Strategy== | ==Treatment Strategy== | ||
*The treatment of small intestine cancer is clinically challenging due to its delayed diagnosis. <ref name="pmid29786046">{{cite journal |vauthors=Tang L, Huang LY, Cui J, Wu CR |title=Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases |journal=Chin. Med. J. |volume=131 |issue=11 |pages=1321–1326 |date=June 2018 |pmid=29786046 |pmc=5987504 |doi=10.4103/0366-6999.232802 |url=}}</ref> | *The treatment of [[small intestine]] cancer is clinically challenging due to its delayed diagnosis. <ref name="pmid29786046">{{cite journal |vauthors=Tang L, Huang LY, Cui J, Wu CR |title=Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases |journal=Chin. Med. J. |volume=131 |issue=11 |pages=1321–1326 |date=June 2018 |pmid=29786046 |pmc=5987504 |doi=10.4103/0366-6999.232802 |url=}}</ref> | ||
*Main stay of the treatment is surgery for these tumors. <ref name="pmid20716869">{{cite journal |vauthors=Ogata Y, Yamaguchi K, Sasatomi T, Uchida S, Akagi Y, Shirouzu K |title=[Treatment and outcome in small bowel cancer] |language=Japanese |journal=Gan To Kagaku Ryoho |volume=37 |issue=8 |pages=1454–7 |date=August 2010 |pmid=20716869 |doi= |url=}}</ref>. | *Main stay of the treatment is surgery for these tumors. <ref name="pmid20716869">{{cite journal |vauthors=Ogata Y, Yamaguchi K, Sasatomi T, Uchida S, Akagi Y, Shirouzu K |title=[Treatment and outcome in small bowel cancer] |language=Japanese |journal=Gan To Kagaku Ryoho |volume=37 |issue=8 |pages=1454–7 |date=August 2010 |pmid=20716869 |doi= |url=}}</ref>. | ||
*Patients with small intestine cancer have many treatment options. | *Patients with [[small intestine]] cancer have many treatment options. | ||
*The selection depends on the the size and location of the tumor, metastasis and comorbidities. | *The selection depends on the the size and location of the tumor, metastasis and comorbidities. | ||
*The options are: | *The options are: | ||
** Surgery | ** Surgery | ||
**Radiation therapy | **[[Radiation therapy]] | ||
**Chemotherapy | **[[Chemotherapy]] | ||
**Combination of methods and palliative treatment. | **Combination of methods and palliative treatment. | ||
*The capecitabine and oxaliplatin are found effective in some studies.<ref name="pmid20716869">{{cite journal |vauthors=Ogata Y, Yamaguchi K, Sasatomi T, Uchida S, Akagi Y, Shirouzu K |title=[Treatment and outcome in small bowel cancer] |language=Japanese |journal=Gan To Kagaku Ryoho |volume=37 |issue=8 |pages=1454–7 |date=August 2010 |pmid=20716869 |doi= |url=}}</ref> | *The capecitabine and oxaliplatin are found effective in some studies.<ref name="pmid20716869">{{cite journal |vauthors=Ogata Y, Yamaguchi K, Sasatomi T, Uchida S, Akagi Y, Shirouzu K |title=[Treatment and outcome in small bowel cancer] |language=Japanese |journal=Gan To Kagaku Ryoho |volume=37 |issue=8 |pages=1454–7 |date=August 2010 |pmid=20716869 |doi= |url=}}</ref> | ||
*[[Side effect]] may not be the same for each person, and they may change from one treatment session to the next. | *[[Side effect]] may not be the same for each person, and they may change from one treatment session to the next. | ||
Revision as of 23:02, 14 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2] Parminder Dhingra, M.D. [3]
Overview
Best treatment for curable small intestine cancer is surgical resection with combination of chemotherapy or radiotherapy. If tumor is not curable palliative surgery can be done.Chemotherapy is used to reduce the likelihood of metastasis developing, shrink tumor size, and slow tumor growth. Chemotherapy is often applied after surgery (adjuvant), before surgery (neo-adjuvant), or as primary therapy if surgery is not indicated (palliative). Other therapies include radiation and support therapies.
Treatment Strategy
- The treatment of small intestine cancer is clinically challenging due to its delayed diagnosis. [1]
- Main stay of the treatment is surgery for these tumors. [2].
- Patients with small intestine cancer have many treatment options.
- The selection depends on the the size and location of the tumor, metastasis and comorbidities.
- The options are:
- Surgery
- Radiation therapy
- Chemotherapy
- Combination of methods and palliative treatment.
- The capecitabine and oxaliplatin are found effective in some studies.[2]
- Side effect may not be the same for each person, and they may change from one treatment session to the next.
References
- ↑ Tang L, Huang LY, Cui J, Wu CR (June 2018). "Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases". Chin. Med. J. 131 (11): 1321–1326. doi:10.4103/0366-6999.232802. PMC 5987504. PMID 29786046.
- ↑ 2.0 2.1 Ogata Y, Yamaguchi K, Sasatomi T, Uchida S, Akagi Y, Shirouzu K (August 2010). "[Treatment and outcome in small bowel cancer]". Gan To Kagaku Ryoho (in Japanese). 37 (8): 1454–7. PMID 20716869.