POEMS syndrome natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
== Natural History == | |||
POEMS syndrome typically presents as a chronic progressive polyneuropathy with both sensory and motor disability, the motor component is usually present to a greater degree than the sensory component of the disease. Many patients may have coexisting multi-organ system disorders such as organomegaly, endocrinopathy (pituitary, thyroid, adrenals), thrombocytosis, anemia, an M-spike (M protein or para-protein) and skin changes. The skin changes include angiomata, hyperpigmentation | |||
== Complications == | |||
== Prognosis == | |||
Revision as of 13:16, 4 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief:
Overview
Natural History
POEMS syndrome typically presents as a chronic progressive polyneuropathy with both sensory and motor disability, the motor component is usually present to a greater degree than the sensory component of the disease. Many patients may have coexisting multi-organ system disorders such as organomegaly, endocrinopathy (pituitary, thyroid, adrenals), thrombocytosis, anemia, an M-spike (M protein or para-protein) and skin changes. The skin changes include angiomata, hyperpigmentation