POEMS syndrome physical examination: Difference between revisions
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== Overview == | == Overview == | ||
Common physical examination findings of POEMS syndrome include, organomegaly (hepatomegaly, splenomegaly), peripheral edema/anasarca, ascites, mixed lytic/sclerotic bone lesions, papilledema, skin hyperpigmentation and lymphadenopathy. | Common physical examination findings of POEMS syndrome include, [[organomegaly]] ([[hepatomegaly]], [[splenomegaly]]), [[peripheral edema]]/[[anasarca]], [[ascites]], mixed lytic/sclerotic [[bone]] lesions, [[papilledema]], [[skin]] [[hyperpigmentation]] and [[lymphadenopathy]]. | ||
==Physical Examination== | ==Physical Examination== | ||
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* [[Hepatomegaly]] | * [[Hepatomegaly]] | ||
* [[Splenomegaly]] | * [[Splenomegaly]] | ||
* Ascites | * [[Ascites]] (succession splash, [[shifting dullness]]) | ||
=== Cardiovascular === | === Cardiovascular === | ||
* Pericardial effusion | * [[Pericardial effusion]] ([[muffled heart sounds]], [[jugular venous distension]]) | ||
=== Respiratory === | === Respiratory === | ||
* Pleural effusion | * [[Pleural effusion]] (decreased or absent breath sounds, decreased [[tactile fremitus]], dullness to [[percussion]]) | ||
=== Musculoskeletal === | === Musculoskeletal === | ||
* Bones may have sclerotic, lytic with sclerotic rims or mixed sclerotic/lytic lesions with soup-bubble appearance | * [[Bones]] may have sclerotic, lytic with sclerotic rims or mixed sclerotic/lytic lesions with soup-bubble appearance | ||
=== Miscellaneous === | === Miscellaneous === | ||
* Lymphadenopathy | * [[Lymphadenopathy]] | ||
==References== | ==References== |
Revision as of 01:39, 6 February 2019
POEMS syndrome Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Common physical examination findings of POEMS syndrome include, organomegaly (hepatomegaly, splenomegaly), peripheral edema/anasarca, ascites, mixed lytic/sclerotic bone lesions, papilledema, skin hyperpigmentation and lymphadenopathy.
Physical Examination
Appearance
Skin
- Hyperpigmentation
- Nail clubbing
- Leuconychia
- Thickening of the skin
- Excess hair or hair in unusual places (hypertrichosis)
- Skin angiomas or haemangiomas
- There may be changes reminiscent of scleroderma
Eye
- Papilloedema
- Uveitis and preretinal haemorrhage may be present.
Abdomen
- Hepatomegaly
- Splenomegaly
- Ascites (succession splash, shifting dullness)
Cardiovascular
Respiratory
- Pleural effusion (decreased or absent breath sounds, decreased tactile fremitus, dullness to percussion)
Musculoskeletal
- Bones may have sclerotic, lytic with sclerotic rims or mixed sclerotic/lytic lesions with soup-bubble appearance