Fanconi anemia risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
There are no particular risk factors for Fanconi anemia, since this is a genetic disorder. | |||
==Risk factors== | ==Risk factors== | ||
Revision as of 05:14, 30 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
There are no particular risk factors for Fanconi anemia, since this is a genetic disorder.
Risk factors
There are no particular risk factors for Fanconi anemia. This is a genetic disorder that is caused by a mutation in genes involved in DNA damage response. Patients with Fanconi anemia are more susceptible to malignancy such as acute myeloid leukemia, and a risk factor for development of malignancies includes exposure to radiation and carcinogens.[1]
References
- ↑ Romick-Rosendale LE, Lui VW, Grandis JR, Wells SI (2013). "The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma". Mutat Res. 743-744: 78–88. doi:10.1016/j.mrfmmm.2013.01.001. PMC 3661751. PMID 23333482.