Subdural hematoma pathophysiology: Difference between revisions
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=== Physiology === | === Physiology === | ||
The normal physiology of | The normal physiology of bridging veins can be understood as follows: | ||
* In embryonic period, there is lots of anastomosis between brain and dura matter venous drainage. | |||
* After 12 weeks of gestation these anastomosis will disappear and what is left from them create bridging veins. | |||
* These vein s will drain venous blood from underlying brain tissue to the dural sinuses. | |||
* Rupture of these bridging vein (mostly due to head trauma) will result in hemorrhage between dura matter and arachnoid, and leads to subdural hematoma. | |||
=== Pathogenesis === | === Pathogenesis === |
Revision as of 13:58, 29 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Physiology
The normal physiology of bridging veins can be understood as follows:
- In embryonic period, there is lots of anastomosis between brain and dura matter venous drainage.
- After 12 weeks of gestation these anastomosis will disappear and what is left from them create bridging veins.
- These vein s will drain venous blood from underlying brain tissue to the dural sinuses.
- Rupture of these bridging vein (mostly due to head trauma) will result in hemorrhage between dura matter and arachnoid, and leads to subdural hematoma.
Pathogenesis
- The exact pathogenesis of [disease name] is not completely understood.
OR
- It is understood that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
- [Pathogen name] is usually transmitted via the [transmission route] route to the human host.
- Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
- [Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
- The progression to [disease name] usually involves the [molecular pathway].
- The pathophysiology of [disease/malignancy] depends on the histological subtype.

Genetics
[Disease name] is transmitted in [mode of genetic transmission] pattern.
OR
Genes involved in the pathogenesis of [disease name] include:
- [Gene1]
- [Gene2]
- [Gene3]
OR
The development of [disease name] is the result of multiple genetic mutations such as:
- [Mutation 1]
- [Mutation 2]
- [Mutation 3]
Associated Conditions
Conditions associated with [disease name] include:
- [Condition 1]
- [Condition 2]
- [Condition 3]
Gross Pathology
On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
Microscopic Pathology
On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].