Subdural hematoma pathophysiology: Difference between revisions
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** Rupture of small cortical atreries and hemorrhage into the space between dura matter and arachnoid, leading to subdural hematoma. | ** Rupture of small cortical atreries and hemorrhage into the space between dura matter and arachnoid, leading to subdural hematoma. | ||
** Intracranial hypotension (mostly due to lumbar punctue) and traction of bridging veins which leads to subdural hematoma | ** Intracranial hypotension (mostly due to lumbar punctue) and traction of bridging veins which leads to subdural hematoma | ||
* Subdural hematomas as a result of arterial rupture accounts for 20% of SDH cases and are mostly in temporoparietal region. | |||
* Since most of the SDH cases are due to vein rupture, the bleeding will stop on its own as a result of a clot formation or increased intracranial pressure. | |||
[[File:Types of Hematoma.jpg|500px|none|thumb|Types of Hematoma|https://commons.wikimedia.org/wiki/File:Types_of_Hematoma.jpg]] | [[File:Types of Hematoma.jpg|500px|none|thumb|Types of Hematoma|https://commons.wikimedia.org/wiki/File:Types_of_Hematoma.jpg]] |
Revision as of 14:33, 29 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Physiology
The normal physiology of bridging veins can be understood as follows:[1]
- In embryonic period, there is lots of anastomosis between brain and dura matter venous drainage.
- After 12 weeks of gestation these anastomosis will disappear and what is left from them create bridging veins.
- These vein s will drain venous blood from underlying brain tissue to the dural sinuses.

Pathogenesis
- It is understood that subdural hematoma is the result of:
- Rupture in bridging veins (mostly due to head trauma) and hemorrhage between dura matter and arachnoid, leading to subdural hematoma.
- Rupture of small cortical atreries and hemorrhage into the space between dura matter and arachnoid, leading to subdural hematoma.
- Intracranial hypotension (mostly due to lumbar punctue) and traction of bridging veins which leads to subdural hematoma
- Subdural hematomas as a result of arterial rupture accounts for 20% of SDH cases and are mostly in temporoparietal region.
- Since most of the SDH cases are due to vein rupture, the bleeding will stop on its own as a result of a clot formation or increased intracranial pressure.

Genetics
[Disease name] is transmitted in [mode of genetic transmission] pattern.
OR
Genes involved in the pathogenesis of [disease name] include:
- [Gene1]
- [Gene2]
- [Gene3]
OR
The development of [disease name] is the result of multiple genetic mutations such as:
- [Mutation 1]
- [Mutation 2]
- [Mutation 3]
Associated Conditions
Conditions associated with [disease name] include:
- [Condition 1]
- [Condition 2]
- [Condition 3]
Gross Pathology
On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
Microscopic Pathology
On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
References
- ↑ Famaey, Nele; Ying Cui, Zhao; Umuhire Musigazi, Grace; Ivens, Jan; Depreitere, Bart; Verbeken, Erik; Vander Sloten, Jos (2015). "Structural and mechanical characterisation of bridging veins: A review". Journal of the Mechanical Behavior of Biomedical Materials. 41: 222–240. doi:10.1016/j.jmbbm.2014.06.009. ISSN 1751-6161.