Liposarcoma CT scan: Difference between revisions

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Latest revision as of 18:45, 29 May 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]Sabawoon Mirwais, M.B.B.S, M.D.[3]

Overview

CT scan is crucial for the diagnosis of liposarcoma. CT scan may detect regions of lipid and non-lipid components that correlate with histological sub-types of liposarcoma. CT scan can demonstrate the size, location, and depth of a liposarcoma, as well as lymph node involvement and distant metastasis.

CT scan

A CT scan image commonly detects areas of focal or diffuse infiltration of lipid and non-lipid components.
The appearance and morphologic relationship between the lipid and non-lipid components of a liposarcoma on CT scan frequently helps in identifying the specific histologic sub-type of liposarcoma.^[1]
CT scan also determines the size and depth of the tumor, stage of the disease, presence of lymphadenopathy, and evidence of distant metastasis.^[2]

CT Scan Findings According to the Liposarcoma Sub-type



Subtypes	Density	Margins	Fat Content	Nodular muscle-density area in tumor	Calcifications	Necrotic or cystic areas
Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL)	Fat	Smooth regular	> 65%	++	Few/none	+
Dedifferentiated liposarcoma (DDL)	Mixed	Rough irregular	30 - 60%	+++	Few/none	++
Myxoid/round cell liposarcoma (ML/RCL)	Mixed	Rough irregular	25 - 50%	+	Common	+++
Pleomorphic liposarcoma (PL)	Soft tissue	Incomplete irregular	6 - 25%	+	Few/none	+
Mixed-type liposarcoma	Mixed	Smooth regular	30 - 60%	++	Common	+
Table adapted from Lu J, Qin Q, Zhan LL, et al. Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma. Asian Pac J Cancer Prev. 2014;15(15):6041-6.^[3]

Images

]

References

↑ Kim, T; Murakami, T; Oi, H; Tsuda, K; Matsushita, M; Tomoda, K; Fukuda, H; Nakamura, H (1996). "CT and MR imaging of abdominal liposarcoma". American Journal of Roentgenology. 166 (4): 829–833. doi:10.2214/ajr.166.4.8610559. ISSN 0361-803X.
↑ Kumarasamy, Narmadan A.; Gayer, Gabriela (2011). "Retroperitoneal Sarcomas". Seminars in Ultrasound, CT and MRI. 32 (5): 422–432. doi:10.1053/j.sult.2011.06.002. ISSN 0887-2171.
↑ Jing Lu, Qin Qin, Liang-Liang Zhan, Xi Yang, Qing Xu, Jing Yu, Li-Na Dou, Hao Zhang, Yan Yang, Xiao-Chen Chen, Yue-Hua Yang, Hong-Yan Cheng & Xin-Chen Sun (2014). "Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma". Asian Pacific journal of cancer prevention : APJCP. 15 (15): 6041–6046. PMID 25124571.

Template:WikiDoc Sources

[KimMurakami1996-1] Kim, T; Murakami, T; Oi, H; Tsuda, K; Matsushita, M; Tomoda, K; Fukuda, H; Nakamura, H (1996). "CT and MR imaging of abdominal liposarcoma". American Journal of Roentgenology. 166 (4): 829–833. doi:10.2214/ajr.166.4.8610559. ISSN 0361-803X.

[KumarasamyGayer2011-2] Kumarasamy, Narmadan A.; Gayer, Gabriela (2011). "Retroperitoneal Sarcomas". Seminars in Ultrasound, CT and MRI. 32 (5): 422–432. doi:10.1053/j.sult.2011.06.002. ISSN 0887-2171.

[3] Jing Lu, Qin Qin, Liang-Liang Zhan, Xi Yang, Qing Xu, Jing Yu, Li-Na Dou, Hao Zhang, Yan Yang, Xiao-Chen Chen, Yue-Hua Yang, Hong-Yan Cheng & Xin-Chen Sun (2014). "Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma". Asian Pacific journal of cancer prevention : APJCP. 15 (15): 6041–6046. PMID 25124571.

[1]

[2]

[3]

@@ Line 4: / Line 4: @@
 ==Overview==
-CT scan is crucial for the diagnosis of liposarcoma. CT scan may detect regions of lipid and non-lipid components that correlate with histological subtypes of liposarcoma. CT scan may demonstrate the size, location, and depth of a liposarcoma, as well as [[lymph node]] involvement and distant [[metastasis]].
+[[Computed tomography|CT scan]] is crucial for the [[diagnosis]] of liposarcoma. [[Computed tomography|CT scan]] may detect regions of [[lipid]] and non-[[lipid]] components that correlate with [[Histology|histological]] sub-types of liposarcoma. [[Computed tomography|CT scan]] can demonstrate the size, location, and depth of a liposarcoma, as well as [[lymph node]] involvement and distant [[metastasis]].
 ==CT scan==
-* A CT image commonly detects areas of focal or diffuse infiltration of lipid and non-lipid components.
+* A [[Computed tomography|CT scan]] image commonly detects areas of focal or diffuse infiltration of [[lipid]] and non-[[lipid]] components.
-* The appearance and morphologic relationship between the lipid and non-lipid components of a liposarcoma on CT scan frequently help in identifying the specific histologic subtype of liposarcoma.<ref name="KimMurakami1996">{{cite journal|last1=Kim|first1=T|last2=Murakami|first2=T|last3=Oi|first3=H|last4=Tsuda|first4=K|last5=Matsushita|first5=M|last6=Tomoda|first6=K|last7=Fukuda|first7=H|last8=Nakamura|first8=H|title=CT and MR imaging of abdominal liposarcoma.|journal=American Journal of Roentgenology|volume=166|issue=4|year=1996|pages=829–833|issn=0361-803X|doi=10.2214/ajr.166.4.8610559}}</ref>
+* The appearance and [[Morphology|morphologic]] relationship between the [[lipid]] and non-[[lipid]] components of a liposarcoma on [[Computed tomography|CT scan]] frequently helps in identifying the specific [[Histology|histologic]] sub-type of liposarcoma.<ref name="KimMurakami1996">{{cite journal|last1=Kim|first1=T|last2=Murakami|first2=T|last3=Oi|first3=H|last4=Tsuda|first4=K|last5=Matsushita|first5=M|last6=Tomoda|first6=K|last7=Fukuda|first7=H|last8=Nakamura|first8=H|title=CT and MR imaging of abdominal liposarcoma.|journal=American Journal of Roentgenology|volume=166|issue=4|year=1996|pages=829–833|issn=0361-803X|doi=10.2214/ajr.166.4.8610559}}</ref>
-* CT scan also determines the size and depth of the tumor, stage of the disease, presence of lymphadenopathy, and evidence of distal metastasis.<ref name="KumarasamyGayer2011">{{cite journal|last1=Kumarasamy|first1=Narmadan A.|last2=Gayer|first2=Gabriela|title=Retroperitoneal Sarcomas|journal=Seminars in Ultrasound, CT and MRI|volume=32|issue=5|year=2011|pages=422–432|issn=08872171|doi=10.1053/j.sult.2011.06.002}}</ref>
+* [[Computed tomography|CT scan]] also determines the size and depth of the [[tumor]], [[Cancer staging|stage]] of the [[disease]], presence of [[lymphadenopathy]], and evidence of distant [[metastasis]].<ref name="KumarasamyGayer2011">{{cite journal|last1=Kumarasamy|first1=Narmadan A.|last2=Gayer|first2=Gabriela|title=Retroperitoneal Sarcomas|journal=Seminars in Ultrasound, CT and MRI|volume=32|issue=5|year=2011|pages=422–432|issn=08872171|doi=10.1053/j.sult.2011.06.002}}</ref>
-===CT Findings According to the Liposarcoma Subtype===
+===CT Scan Findings According to the Liposarcoma Sub-type===
-{| style="border: 0px; font-size: 90%; margin: 3px; width: 900px;" align=center
+{| style="border: 0px; font-size: 90%; margin: 3px; width: 900px;" align="center"
-|valign=top|
+| valign="top" |
 |+
 | style="padding: 5px 5px; background: #4479BA; font-weight: bold; width: 300px; text-align:center" | {{fontcolor|#FFF|Subtypes}}
@@ Line 23: / Line 23: @@
 |-
 | style="padding: 5px 5px; background: #4479BA; font-weight: bold;" | {{fontcolor|#FFF|Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL)}}
-| style="padding: 5px 5px; background: #DCDCDC;" | Fat
+| style="padding: 5px 5px; background: #DCDCDC;" | [[Fat]]
 | style="padding: 5px 5px; background: #F5F5F5;" | Smooth regular
 | style="padding: 5px 5px; background: #DCDCDC;" | > 65%
@@ Line 33: / Line 33: @@
 | style="padding: 5px 5px; background: #DCDCDC;" | Mixed
 | style="padding: 5px 5px; background: #F5F5F5;" | Rough irregular
-| style="padding: 5px 5px; background: #DCDCDC;" | 30-60%
+| style="padding: 5px 5px; background: #DCDCDC;" | 30 - 60%
 | style="padding: 5px 5px; background: #F5F5F5;" | +++
 | style="padding: 5px 5px; background: #DCDCDC;" | Few/none
@@ Line 41: / Line 41: @@
 | style="padding: 5px 5px; background: #DCDCDC;" | Mixed
 | style="padding: 5px 5px; background: #F5F5F5;" | Rough irregular
-| style="padding: 5px 5px; background: #DCDCDC;" | 25-50%
+| style="padding: 5px 5px; background: #DCDCDC;" | 25 - 50%
 | style="padding: 5px 5px; background: #F5F5F5;" | +
 | style="padding: 5px 5px; background: #DCDCDC;" | Common
@@ Line 47: / Line 47: @@
 |-
 | style="padding: 5px 5px;background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Pleomorphic liposarcoma (PL)}}
-| style="padding: 5px 5px; background: #DCDCDC;" | Soft tissue
+| style="padding: 5px 5px; background: #DCDCDC;" | [[Soft tissue]]
 | style="padding: 5px 5px; background: #F5F5F5;" | Incomplete irregular
-| style="padding: 5px 5px; background: #DCDCDC;" | 6-25%
+| style="padding: 5px 5px; background: #DCDCDC;" | 6 - 25%
 | style="padding: 5px 5px; background: #F5F5F5;" | +
 | style="padding: 5px 5px; background: #DCDCDC;" | Few/none
@@ Line 57: / Line 57: @@
 | style="padding: 5px 5px; background: #DCDCDC;" | Mixed
 | style="padding: 5px 5px; background: #F5F5F5;" |Smooth regular
-| style="padding: 5px 5px; background: #DCDCDC;" | 30-60%
+| style="padding: 5px 5px; background: #DCDCDC;" | 30 - 60%
 | style="padding: 5px 5px; background: #F5F5F5;" | ++
 | style="padding: 5px 5px; background: #DCDCDC;" | Common
 | style="padding: 5px 5px; background: #F5F5F5;" | +
 |-
-| style="padding: 5px 5px; background: #F5F5F5;" colspan=7|<small> Table adapted from Lu J, Qin Q, Zhan LL, et al. Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma. ''Asian Pac J Cancer Prev''. 2014;15(15):6041-6.<ref>{{Cite journal
+| colspan="7" style="padding: 5px 5px; background: #F5F5F5;" |<small> Table adapted from Lu J, Qin Q, Zhan LL, et al. Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma. ''Asian Pac J Cancer Prev''. 2014;15(15):6041-6.<ref>{{Cite journal
 | author = [[Jing Lu]], [[Qin Qin]], [[Liang-Liang Zhan]], [[Xi Yang]], [[Qing Xu]], [[Jing Yu]], [[Li-Na Dou]], [[Hao Zhang]], [[Yan Yang]], [[Xiao-Chen Chen]], [[Yue-Hua Yang]], [[Hong-Yan Cheng]] & [[Xin-Chen Sun]]
   | title = Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma
@@ Line 75: / Line 75: @@
 |}
 ==Images==
-[[File:Lipsarcoma CT.jpg|400px|left|thumb|CT scan image showing retroperitoneal liposarcoma. [https://radiopaedia.org/articles/liposarcoma?lang=us Source: Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID: 7623]]]
+[[File:Lipsarcoma CT.jpg|400px|left|thumb|[[Computed tomography|CT scan]] image showing [[Retroperitoneum|retroperitoneal]] liposarcoma. [https://radiopaedia.org/articles/liposarcoma?lang=us Source: Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID: 7623]]]
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