Liposarcoma MRI: Difference between revisions
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==Overview== | ==Overview== | ||
MRI is the optimal imaging test for the diagnosis of liposarcoma. | [[Magnetic resonance imaging|MRI]] is the optimal [[imaging]] [[test]] for the [[diagnosis]] of liposarcoma. [[Magnetic resonance imaging|MRI]] findings for a well-differentiated liposarcoma include a mass with at least 75% of [[adipose]] content with thin irregular [[septa]]. [[Magnetic resonance imaging|MRI]] also evaluates the size, location, and depth of the mass. [[Magnetic resonance imaging|MRI]] findings help to differentiate between the different sub-types of liposarcoma and also help to assess distant [[metastasis]]. | ||
==MRI== | ==MRI== | ||
*MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of [[adipose]] content with thin irregular [[septa]]. <ref name="PetersonKransdorf2003">{{cite journal|last1=Peterson|first1=Jeffrey J.|last2=Kransdorf|first2=Mark J.|last3=Bancroft|first3=Laura W.|last4=O'Connor|first4=Mary I.|title=Malignant fatty tumors: classification, clinical course, imaging appearance and treatment|journal=Skeletal Radiology|volume=32|issue=9|year=2003|pages=493–503|issn=0364-2348|doi=10.1007/s00256-003-0647-8}}</ref> | *[[Magnetic resonance imaging|MRI]] findings for a well-differentiated liposarcoma include a mass with at least 75% of [[adipose]] content with thin irregular [[septa]].<ref name="PetersonKransdorf2003">{{cite journal|last1=Peterson|first1=Jeffrey J.|last2=Kransdorf|first2=Mark J.|last3=Bancroft|first3=Laura W.|last4=O'Connor|first4=Mary I.|title=Malignant fatty tumors: classification, clinical course, imaging appearance and treatment|journal=Skeletal Radiology|volume=32|issue=9|year=2003|pages=493–503|issn=0364-2348|doi=10.1007/s00256-003-0647-8}}</ref> | ||
*Other | *Other sub-types may demonstrate fewer [[adipose]] content. | ||
*Thick [[septa]] inside the mass are associated with a [[malignant]] disease and poorer prognosis. | *Thick [[septa]] inside the mass are associated with a [[malignant]] [[disease]] and poorer [[prognosis]]. | ||
*[[Hemorrhage]] and [[necrosis]] may be observed within the mass among patients with the de-differentiated | *[[Hemorrhage]] and [[necrosis]] may be observed within the mass among [[Patient|patients]] with the de-differentiated sub-type of liposarcoma. | ||
*Typically, myxoid liposarcoma has a low signal intensity on T1, in contrast to well-differentiated liposarcoma | *Typically, myxoid liposarcoma has a low signal intensity on T1, in contrast to well-differentiated liposarcoma which has a high intensity signal on T1 due to the presence of high [[adipose]] content.<ref>{{Cite journal | ||
| author = [[M. S. Sung]], [[H. S. Kang]], [[J. S. Suh]], [[J. H. Lee]], [[J. M. Park]], [[J. Y. Kim]] & [[H. G. Lee]] | | author = [[M. S. Sung]], [[H. S. Kang]], [[J. S. Suh]], [[J. H. Lee]], [[J. M. Park]], [[J. Y. Kim]] & [[H. G. Lee]] | ||
| title = Myxoid liposarcoma: appearance at MR imaging with histologic correlation | | title = Myxoid liposarcoma: appearance at MR imaging with histologic correlation | ||
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| pmid = 10903690 | | pmid = 10903690 | ||
}}</ref> | }}</ref> | ||
*The myxoid | *The myxoid sub-type may be associated with a [[cystic]] appearance on [[Magnetic resonance imaging|MRI]] among approximately 20% of cases. The myxoid sub-type may also appear [[Lobule|multilobulated]]. <ref>{{Cite journal | ||
| author = [[M. S. Sung]], [[H. S. Kang]], [[J. S. Suh]], [[J. H. Lee]], [[J. M. Park]], [[J. Y. Kim]] & [[H. G. Lee]] | | author = [[M. S. Sung]], [[H. S. Kang]], [[J. S. Suh]], [[J. H. Lee]], [[J. M. Park]], [[J. Y. Kim]] & [[H. G. Lee]] | ||
| title = Myxoid liposarcoma: appearance at MR imaging with histologic correlation | | title = Myxoid liposarcoma: appearance at MR imaging with histologic correlation | ||
| Line 37: | Line 37: | ||
{| | {| | ||
|[[File: Myxoid Liposarcoma of the Thigh.jpg |thumb|320px|Myxoid Liposarcoma Large soft tissue mass is noted at the medial posterior portion of the lower part of the left thigh. | |[[File: Myxoid Liposarcoma of the Thigh.jpg |thumb|320px|Myxoid Liposarcoma: Large [[soft tissue]] mass is noted at the [[Anatomical terms of location|medial]] [[Anatomical terms of location|posterior]] portion of the lower part of the left [[thigh]]. It has an isointense signal to the adjacent [[Muscle|muscles]] on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating [[Fat|fatty]] component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-[[gadolinium]] [[Injection (medicine)|injection]]. <br> Image courtesy of Radiopaedia.org]] | ||
|[[File: Myxoid Liposarcoma of the Thigh 2.jpg |thumb|320px|Myxoid Liposarcoma Large soft tissue mass is noted at the medial posterior portion of the lower part of the left thigh. | |[[File: Myxoid Liposarcoma of the Thigh 2.jpg |thumb|320px|Myxoid Liposarcoma: Large [[soft tissue]] mass is noted at the [[Anatomical terms of location|medial]] [[Anatomical terms of location|posterior]] portion of the lower part of the left [[thigh]]. It has an isointense signal to the adjacent [[Muscle|muscles]] on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating [[Fat|fatty]] component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-[[gadolinium]] [[Injection (medicine)|injection]]. <br> Image courtesy of Radiopaedia.org]] | ||
|[[File: Myxoid Liposarcoma of the Thigh 3.jpg |thumb|320px|Myxoid Liposarcoma Large soft tissue mass is noted at the medial posterior portion of the lower part of the left thigh. | |[[File: Myxoid Liposarcoma of the Thigh 3.jpg |thumb|320px|Myxoid Liposarcoma: Large [[soft tissue]] mass is noted at the [[Anatomical terms of location|medial]] [[Anatomical terms of location|posterior]] portion of the lower part of the left [[thigh]]. It has an isointense signal to the adjacent [[Muscle|muscles]] on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating [[Fat|fatty]] component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-[[gadolinium]] [[Injection (medicine)|injection]]. <br> Image courtesy of Radiopaedia.org]] | ||
|} | |} | ||
Revision as of 19:04, 29 May 2019
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Liposarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Liposarcoma MRI On the Web |
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American Roentgen Ray Society Images of Liposarcoma MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
MRI is the optimal imaging test for the diagnosis of liposarcoma. MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of adipose content with thin irregular septa. MRI also evaluates the size, location, and depth of the mass. MRI findings help to differentiate between the different sub-types of liposarcoma and also help to assess distant metastasis.
MRI
- MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of adipose content with thin irregular septa.[1]
- Other sub-types may demonstrate fewer adipose content.
- Thick septa inside the mass are associated with a malignant disease and poorer prognosis.
- Hemorrhage and necrosis may be observed within the mass among patients with the de-differentiated sub-type of liposarcoma.
- Typically, myxoid liposarcoma has a low signal intensity on T1, in contrast to well-differentiated liposarcoma which has a high intensity signal on T1 due to the presence of high adipose content.[2]
- The myxoid sub-type may be associated with a cystic appearance on MRI among approximately 20% of cases. The myxoid sub-type may also appear multilobulated. [3]
 Image courtesy of Radiopaedia.org |
 Image courtesy of Radiopaedia.org |
 Image courtesy of Radiopaedia.org |
References
- ↑ Peterson, Jeffrey J.; Kransdorf, Mark J.; Bancroft, Laura W.; O'Connor, Mary I. (2003). "Malignant fatty tumors: classification, clinical course, imaging appearance and treatment". Skeletal Radiology. 32 (9): 493–503. doi:10.1007/s00256-003-0647-8. ISSN 0364-2348.
- ↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter
|month=ignored (help) - ↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter
|month=ignored (help)