Adrenal insufficiency causes: Difference between revisions
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The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click [[Pericarditis causes#Overview|here]]. | The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click [[Pericarditis causes#Overview|here]]. | ||
==Cause[[ | ==Cause[[Adrenal insufficiency |Causes]]== | ||
===Life threatening cause=== | |||
* | *[[Adrenal crisis]] is a life-threatening cause of [[adrenal insufficiency]]. | ||
===Common Causes=== | ===Common Causes=== | ||
Common causes of [ | Common causes of [adrenal insufficiency] include: | ||
*[ | *[[Primary adrenal insufficiency]]: [[Autoimmune adrenalitis]] | ||
*[ | *[[Central adrenal insufficiency]]: Chronic [[glucocorticoid]] use. | ||
===Less Common Causes=== | |||
Less common causes of [[adrenal insufficiency]] include: | |||
*Infections: | |||
**[[Tuberculosis]] | |||
**Fungal infections([[histoplasma]]) | |||
**[[Cytomegalovirus]] | |||
**[[HIV]] | |||
*[[Adrenal hemorrhage]] | |||
*[[X-linked adrenoleukodystrophy]] | |||
*Trauma | |||
*[[Metastasis]] | |||
The following table summarizes the causes of adrenal insufficiency. <ref name="pmid25905309">{{cite journal| author=Feingold KR, Anawalt B, Boyce A, Chrousos G, de Herder WW, Dungan K | display-authors=etal| title=Endotext | journal= | year= 2000 | volume= | issue= | pages= | pmid=25905309 | doi= | pmc= | url= }} </ref> <ref name="BornsteinAllolio2016">{{cite journal|last1=Bornstein|first1=Stefan R.|last2=Allolio|first2=Bruno|last3=Arlt|first3=Wiebke|last4=Barthel|first4=Andreas|last5=Don-Wauchope|first5=Andrew|last6=Hammer|first6=Gary D.|last7=Husebye|first7=Eystein S.|last8=Merke|first8=Deborah P.|last9=Murad|first9=M. Hassan|last10=Stratakis|first10=Constantine A.|last11=Torpy|first11=David J.|title=Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline|journal=The Journal of Clinical Endocrinology & Metabolism|volume=101|issue=2|year=2016|pages=364–389|issn=0021-972X|doi=10.1210/jc.2015-1710}}</ref> | |||
{| class="wikitable" | |||
|+ | |||
! colspan="3" |<font size="+2">Causes of [[adrenal insufficiency]] | |||
|- | |||
|'''<font size="+1">[[Primary adrenal insufficiency]]'''<br>'''([[Addison's disease]])''' | |||
|'''<font size="+1">[[Secondary adrenal insufficiency]]''' | |||
|'''<font size="+1">[[Tertiary adrenal insufficiency]]''' | |||
|- | |||
| | |||
*'''[[Autoimmune]]:''' | |||
**Sporadic | |||
**[[Autoimmune polyglandular syndrome type 1]]<br>(APS type 1) | |||
**[[Autoimmune polyglandular syndrome type 2]]<br>(Schmidt's syndrome) | |||
*'''[[Infections]]:''' | |||
**[[Tuberculosis]], | |||
**[[Fungal infections]], | |||
**[[Cytomegalovirus]], | |||
**[[HIV]] | |||
*'''[[Adrenal]] [[Metastasis]]''' | |||
*'''[[Adrenal]] infiltration''' | |||
*'''[[Adrenal hemorrhage]]:''' | |||
**[[Waterhouse-Friderichsen syndrome]], | |||
**Drugs - Anticoagulants- [[Heparin]], [[Warfarin]]) | |||
*'''[[Adrenoleukodystrophy]]''' | |||
*'''Congenital adrenal hypoplasia''' | |||
*'''Bilateral adrenelectomy''' | |||
*[ | | | ||
*[ | *'''[[Pituitary]] [[tumors]]''' | ||
*'''[[Iatrogeneic]]:''' | |||
**[[Pituitary]] [[surgery]], | |||
**[[Pituitary]] [[radiation]] | |||
*'''[[Granulomatous diseases]]:''' | |||
**[[Tuberculosis]] | |||
**[[Sarcoidosis]] | |||
**[[Histiocytosis]] | |||
**[[Wegener's granulomatosis]] | |||
*'''[[Metastasis]]''' | |||
*'''[[Pituitary apoplexy]]''' | |||
*'''[[Sheehan's syndrome]]'''<br>(Peripartum pituitary necrosis) | |||
*'''[[Genetic]]:''' | |||
**Isolated [[ACTH]] deficiency, | |||
**Multiple pituitary hormone deficiencies | |||
*'''Trauma''' | |||
| | |||
*'''[[Glucocorticoid]] therapy''' | |||
*'''[[Cushing's syndrome]]'''<br>(Excess endogenous [[glucocorticoid]] production) | |||
*'''Drugs:''' | |||
**[[Mifepristone]] | |||
**[[Chlorpromazine]] | |||
**[[Imipramine]] | |||
*'''[[Hypothalamic]] tumors'''<br>(Primary and metastatic) | |||
*'''[[Iatrogenic]]:''' | |||
**[[Hypothalamic]] [[surgery]] | |||
**[[Hypothalamic]] [[radiation]] | |||
*'''[[Granulomatous diseases]]:''' | |||
**[[Tuberculosis]] | |||
**[[Sarcoidosis]] | |||
**[[Histiocytosis]] | |||
**[[Wegener's granulomatosis]] | |||
*'''Trauma''' | |||
|} | |||
==References== | ==References== |
Revision as of 21:41, 22 October 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Disease name] may be caused by [cause1], [cause2], or [cause3].
OR
Common causes of [disease] include [cause1], [cause2], and [cause3].
OR
The most common cause of [disease name] is [cause 1]. Less common causes of [disease name] include [cause 2], [cause 3], and [cause 4].
OR
The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click here.
CauseCauses
Life threatening cause
- Adrenal crisis is a life-threatening cause of adrenal insufficiency.
Common Causes
Common causes of [adrenal insufficiency] include:
- Primary adrenal insufficiency: Autoimmune adrenalitis
- Central adrenal insufficiency: Chronic glucocorticoid use.
Less Common Causes
Less common causes of adrenal insufficiency include:
- Infections:
- Tuberculosis
- Fungal infections(histoplasma)
- Cytomegalovirus
- HIV
- Adrenal hemorrhage
- X-linked adrenoleukodystrophy
- Trauma
- Metastasis
The following table summarizes the causes of adrenal insufficiency. [1] [2]
Causes of adrenal insufficiency | ||
---|---|---|
Primary adrenal insufficiency (Addison's disease) |
Secondary adrenal insufficiency | Tertiary adrenal insufficiency |
|
|
|
References
- ↑ Feingold KR, Anawalt B, Boyce A, Chrousos G, de Herder WW, Dungan K; et al. (2000). "Endotext". PMID 25905309.
- ↑ Bornstein, Stefan R.; Allolio, Bruno; Arlt, Wiebke; Barthel, Andreas; Don-Wauchope, Andrew; Hammer, Gary D.; Husebye, Eystein S.; Merke, Deborah P.; Murad, M. Hassan; Stratakis, Constantine A.; Torpy, David J. (2016). "Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline". The Journal of Clinical Endocrinology & Metabolism. 101 (2): 364–389. doi:10.1210/jc.2015-1710. ISSN 0021-972X.