Adrenal insufficiency natural history, complications and prognosis: Difference between revisions
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===Complications=== | ===Complications=== | ||
*Common complications of [ | *Common complications of [[adrenal insufficiency]] include: <ref>{{cite web |url=https://www.amjmed.com/article/S0002-9343(15)00827-X/pdf |title=www.amjmed.com |format= |work= |accessdate=}}</ref> | ||
**[ | **Sleep disturbance due to disruption of [[circadian]] rhythm. | ||
**[ | **Decreased bone mineral density as a consequence of [[glucocorticoid]] therapy. | ||
**[ | **[[Fertility]] and pregnancy complications: Reduced [[fertility]], increased risk of [[fetal growth restriction]], [[preterm birth]], [[cesarean]] delivery | ||
===Prognosis=== | ===Prognosis=== | ||
Revision as of 03:08, 23 October 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of adrenal insufficiency usually develop in the third to fifth decade of life, and start with symptoms such as fatigue, anorexia, weight loss, nausea, abdominal pain.
- If left untreated, chronic adrenal insufficiency in the presence of precipitating factors can develop adrenal crisis presenting with acute hemodynamic compromise. [1]
Complications
- Common complications of adrenal insufficiency include: [2]
- Sleep disturbance due to disruption of circadian rhythm.
- Decreased bone mineral density as a consequence of glucocorticoid therapy.
- Fertility and pregnancy complications: Reduced fertility, increased risk of fetal growth restriction, preterm birth, cesarean delivery
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
- Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Pazderska, Agnieszka; Pearce, Simon HS (2017). "Adrenal insufficiency – recognition and management". Clinical Medicine. 17 (3): 258–262. doi:10.7861/clinmedicine.17-3-258. ISSN 1470-2118.
- ↑ "www.amjmed.com".